Sidi Chen

Gene editing. Technology. Cancer. Immunology. Cell and gene therapy. Antibody. mRNA vaccine. @ Yale Genetics & Systems Biology. ## CRISPR in vivo ##

[Sidi Chen @sidichen]

Excited to share our new Nature paper on in vivo CAR-NK CRISPRa screen + discovery of a hyperbooster for solid tumor https://t.co/J4gBc5aYDM Tx to Luojia, Paul, Drs Peng, Gunel, Moliterno, J Chen. #NK cell therapy @Yalegenetics @yalewestcampus @yalemed @yalecancer @yneurosurgery

[Sidi Chen @sidichen]

Proud to share our new work at Nature biomedical engineering on mRNA vaccine platform innovation! https://t.co/zQfVi00vfR @Carolina Lucas @zane_zhenhao Fang @Yale @YaleGenetics @YaleWestCampus

[Sidi Chen @sidichen]

Proud to present our work at #KCRS25 on CAR-T screens, cell therapy and kidney cancer from @YaleMed @YaleGenetics @YaleWestCampus @YaleCancer Honored to be in session with Drs. Chuck Drake at JnJ, Nadal Rios at Hutch & Patrick Ott at Farber, hosted by David Braun &Hans Hammers.

[KidneyCAN @kidneycan]

#KCRS25 Session 6 highlighted how researchers are pushing the boundaries of what immunotherapy can do for kidney cancer patients.

Engaging Native Immunity with ENPP3 with Chuck Drake
TCR-Engineered Cell Therapy with @RosaNadalrios
Next Generation T-Cell Engineering with @sidichen
Future of Cancer Vaccines with Patrick Ott

#AcceleratingCures

[Cancer Research Institute @CancerResearch]

🎉 CRI is proud to announce the 2025 CLIP and Technology Impact Award projects, a new class of high‑potential studies and tools designed to push cancer immunotherapy further and faster! Explore: https://t.co/k9UzH3v2zy #Immunotherapy #CancerResearch #CancerResearcher

[Sidi Chen @sidichen]

Organizing an AI symposium on 6/20 with SAPA-CT at Yale. Please check it out and all are welcome to register/attend! @YaleWestCampus

[Sidi Chen @sidichen]

Excited to present our new work on multiplex immune gene therapies for cancer @ASGCT 2025 @NOLA @YaleMed @YaleCancer @YaleGenetics @YaleWestCampus

[Yale Cancer Center @YaleCancer]

.@sidichen co-chairs a symposium highlighting the transformative field of adoptive cell therapies for #cancer treatment #AACR25 with Dr. Daniel Powell @PennMedicine @AACR @SmilowCancer @YaleWestCampus @YaleGenetics

[Sidi Chen @sidichen]

Our lab generated 4 new lines of Cas12a transgenic mice and demonstrated utility in immune engineering, tumor modeling, and genetic disease treatment. Around to share w the field & community! @YaleMed @YaleWest @YaleGenetics @YaleData Also @LabWinslow https://t.co/LROOO0qmF8

[Sidi Chen @sidichen]

Our new “MUCIG” therapy @FF Zhang ⁦@ScienceChow⁩ @GW ⁩ ⁦@YaleCancer⁩ ⁦@YaleGenetics⁩ ⁦@YaleWestCampus⁩
Multiplexed inhibition of immunosuppressive genes with Cas13d for combinatorial cancer immunotherapy | Nature Biotechnology https://t.co/3YlzzODFXX

[Sidi Chen @sidichen]

Our team’s new work “MUCIG” cancer therapy - Multi-target approach counters tumor growth in several cancers | Yale News @Feifei Zhang ⁦@ScienceChow⁩ @Guangchuan Wang ⁦@Yale⁩ ⁦@YaleCancer⁩ ⁦@YaleGenetics⁩ ⁦@YaleWestCampus⁩ https://t.co/YpZNojMG25

[Sidi Chen @sidichen]

@jmuiuc @CarnegieMellon @SCSatCMU Great congrats! Exciting area and time!

[Sidi Chen @sidichen]

@RongFan8 @MinaXu7 @Halene_lab @ZongmingMa @YaleCancer @YaleEngineering @YaleMed Congrats!

[Sidi Chen @sidichen]

@pdhsu Check out the origin of new genes

[Sidi Chen @sidichen]

Honored to serve on the panel of #AI for drug discovery in biomedicine at #AIME 2024 Utah. Very stimulating discussions on future of medicine, challenges etc, with experts and audience. @YaleData @yaledatascience @YaleGenetics @YaleCancer @Yale_Ventures

[Sidi Chen @sidichen]

@pdhsu @Nature Very cool tech!

[Sidi Chen @sidichen]

Our first in vivo primary NK screen that discovered new NK cellular checkpoints. Kudos for team for their 5 years of work. https://t.co/d0e3Bguzou @YaleGenetics @YaleMed @YaleWestCampus @YaleCancer @YaleData

[MIT Jameel Clinic for AI & Health @AIHealthMIT]

“Building a community and paying attention to that community is the essence of getting things done.”
Today #JameelClinic Advisory Board Chair and Nobel laureate Phil Sharp celebrated the 50th anniversary of his lab, “The Sharpies” — half a century of sharp minds!

[Sidi Chen @sidichen]

Our new high fidelity enhanced AsCas12a/Cpf1 transgenic mice after five years of work. Generated by Matt Dong and colleagues here in lab at @YaleGenetics @YaleCancer @YaleMed @YaleWestCampus Anyone who want to try them out feel free to please contact us. https://t.co/Wxtuq1ju2Z

[Sidi Chen @sidichen]

Got the cover for this one as well at Nature Biomedical Engineering :)

[Sidi Chen @sidichen]

Our new piece of tools for gene delivery and cell therapy.https://t.co/ccNXqx4koj
https://t.co/izXMntvHb8 @YaleGenetics @YaleMed @YaleWestCampus @YaleData @YaleCancer