John M. Brimacombe

Entrepreneur, Executive and Angel Investor

[Daniel Hannan @DanielJHannan]

Well done, @JohnHealey_MP. We prioritise disability benefits over drones. The MoD can’t get the £28 billion which it needs to keep us safe, yet the welfare budget is set to rise by £42 billion.
We spend more than 5️⃣ times as much on social security as on actual security.

[Sama Hoole @SamaHoole]

Every hospital in Britain had a stockpot on the stove until approximately the 1960s. Every workhouse before that. Every military mess. Every school kitchen. Every farmhouse. Every household that could afford bones, which was every household, because bones were the cheapest thing the butcher sold.

The stockpot ran continuously. Beef bones, pork bones, chicken carcasses, lamb shanks. The bones went in with water and were simmered for 12, 18, 24 hours. The broth that came out was the foundation of every soup, every stew, every gravy, every sauce.

Bone broth contains collagen, which breaks down into gelatin during cooking. Gelatin provides glycine and proline, essential for joint health, gut lining integrity, and connective tissue repair. It contains calcium, magnesium, phosphorus, and potassium leached from the bones. It contains glucosamine and chondroitin, now sold as joint supplements at £15 per bottle. It contains bone marrow, rich in fat-soluble vitamins A, D, and K2.

Your grandmother did not know the names of these compounds. She knew the broth kept the family well. She knew a bowl of broth settled the stomach when someone was ill. She knew the broth made the gravy and the gravy made the dinner and the dinner kept the children growing.

The broth was replaced by the stock cube.

The stock cube contains salt, maltodextrin, palm oil, yeast extract, flavouring, sugar, and colouring. It does not contain collagen, glycine, glucosamine, or any of the compounds the 24-hour broth provided. The stock cube is flavoured salt water.

The generation that grew up on the broth has joints. The generation that grew up on the stock cube has a glucosamine subscription and an orthopaedic appointment.

The supplement industry now sells, individually and at substantial markup, every compound the bone broth contained for free. Collagen powder: £25. Glucosamine tablets: £15. Bone broth itself, repackaged as a wellness product: £8 per serving from a company in Shoreditch with a minimalist label.

They have not discovered anything new. They have rediscovered what their grandmothers threw away.

The stockpot is still available. The bones are still at the butcher's. Water. Bones. Heat. Time.

The broth has been the broth for approximately 10,000 years.

The stock cube has been the stock cube for approximately 70.

The broth's track record is better.

[Brivael Le Pogam @brivael]

Milton Friedman (prix nobel d'économie) a dit un truc il y a 50 ans qui est encore plus vrai aujourd'hui. Et quasiment personne ne le comprend.

🧵

On lui pose la question : "Sans régulation sur les médicaments, des gens pourraient mourir en prenant des produits dangereux. Vous ne trouvez pas ça grave ?"

Sa réponse est un des retournements logiques les plus brillants de l'histoire de l'économie.

Oui, dit Friedman. Un médicament non régulé peut tuer des gens. C'est visible. C'est dans les journaux. C'est un scandale. Tout le monde le voit.

Mais ce que personne ne voit, c'est les gens qui meurent parce qu'un médicament qui aurait pu les sauver a été bloqué pendant 10 ans par le processus de régulation. Ce mort là, personne ne le compte. Personne ne fait sa une. Personne ne connaît son nom. Parce qu'il est mort de l'absence de quelque chose qui n'a jamais existé.

C'est l'asymétrie fondamentale de la régulation.

Le régulateur a deux types d'erreurs possibles. Erreur 1 : approuver un médicament dangereux. Résultat : scandale public, procès, le régulateur perd son poste. Erreur 2 : bloquer un médicament qui aurait sauvé des vies. Résultat : rien. Personne ne sait. Personne ne proteste. Les morts silencieux n'ont pas de porte-parole.

Du coup, le régulateur rationnel optimise pour éviter l'erreur 1. Toujours. Il rajoute des études. Des phases. Des comités. Des délais. Chaque couche de "sécurité" supplémentaire le protège, lui, au détriment des patients qui attendent.

Friedman estimait que la FDA avait probablement tué plus de gens en retardant des bons médicaments qu'elle n'en avait sauvé en bloquant des mauvais. C'est impossible à prouver précisément. Mais la logique est imparable.

Un exemple concret. Le bêta-bloquant Propranolol était disponible en Europe des années avant d'être approuvé aux États-Unis. Pendant ces années, des Américains mouraient de crises cardiaques qui auraient pu être évitées. Combien ? On ne le saura jamais. Parce qu'on ne compte pas les morts de l'inaction.

C'est le même principe partout. Pas que dans la médecine.

En France, les taxis autonomes sont bloqués par la régulation. Chaque année de retard, ce sont des accidents de la route qui auraient pu être évités. Mais personne ne compte ces morts là. On compte uniquement le premier accident d'un taxi autonome, qui fera la une de tous les journaux.

L'IA dans la médecine est ralentie par des processus d'approbation qui prennent des années. Des diagnostics qui pourraient être faits en secondes par un algorithme attendent des validations pendant que des patients attendent des mois pour un rendez-vous.

Le nucléaire a été bloqué pendant des décennies par la peur. Combien de gens sont morts de la pollution des centrales à charbon qui ont tourné à la place ? Personne ne les compte.

Le pattern est toujours le même. On voit le risque de l'action. On ne voit jamais le risque de l'inaction. Et comme le risque de l'inaction est invisible, le régulateur choisit toujours l'inaction. Parce que l'inaction ne produit pas de scandale.

Friedman résumait ça en une phrase : "Les gens qui ont été sauvés par la FDA sont visibles. Les gens qui sont morts à cause des retards de la FDA sont invisibles. Et dans une démocratie, le visible gagne toujours contre l'invisible."

La prochaine fois que quelqu'un vous dit "il faut plus de régulation pour protéger les gens", posez une seule question : combien de gens meurent en attendant que la régulation les autorise à vivre ?

La réponse est toujours plus grande que ce qu'on imagine. Mais personne ne la calcule. Parce que les morts de l'inaction n'ont pas de visage.

[Will Tanner @Will_Tanner_1]

"For the average person, all problems date to World War II; for the more informed, to World War I; for the genuine historian, to the French Revolution."

-Erik von Kuehnelt-Leddihn

[Matt Shumer @mattshumer_]

https://t.co/ivXRKXJvQg

[Zachary Werrell, Esq. @zkwerrell]

Aside from the lawsuits, we can still beat this redistricting effort at the ballot box (if it happens).

The messaging is this.

Frederick County, you get to be represented by one congressman from Fairfax.

The rest of the Northern Valley, you get to be represented by the second congressman from Fairfax.

From Augusta through Culpeper and down to Cumberland, you get to be represented by the third congressman from Fairfax.

Hanover, King William, Spotsy, you get to be represented by the fourth congressman from Fairfax.

Northern Neck, Middle Peninsula? Yep, you guessed it, you get to be represented by the fifth congressman from Fairfax.

Southside, don’t worry though. You won’t be represented by a congressman from Fairfax.

From Danville, all you counties bordering North Carolina, and up through Dinwiddie you get to be represented by one of the congressmen from Richmond.

Campbell, Appomattox, Prince Edward, etc, you all get to be represented by the other congressman from Richmond.

Finally, Lynchburg, and Bedford, you get to be represented by the congressman from Charlottesville.

I don’t know if the Democrats have the enthusiasm to match what will be an enraged Republican majority of the state who doesn’t want to be represented by Fairfax or Richmond. If they really wanted to pour gasoline on the ROVA-NOVA, urban-rural divide in Virginia, they just did so.

I pray this backfires spectacularly.

@VApoliticalmeme @ProjectVirginia

[John M. Brimacombe @skylander2000]

@grok Why are you struggling with queries tonight ?

[Annunziata Rees-Mogg @zatzi]

I’ve never hunted and have no desire to start. But this is spot on👇

“This isn’t about animal welfare.
It’s ideology over reality
And rural communities will pay the price.”

[Daniel Hannan @DanielJHannan]

Do you understand what the customs union is? Do you grasp that it would mean junking all our trade deals, but would not mean an end to physical goods checks by the EU?
Do you comprehend that it applies asymmetrically, so that Britain would be obliged to follow any EU liberalisation vis-à-vis third countries, but those third countries would have to reciprocate only with the EU, not with Britain (see, for example, the way the EU’s trade deal with South Korea applies to Turkey)?
Did you notice that, while we were in the EU, we were the only country that exported more outside the bloc than to it, making the customs union much more problematic for us than for any other member state?
If you want to rejoin the EU, fine, make the case. We’ll disagree, but at least there is a coherent rationale for going back in.
If you want to argue for the single market, or for free movement of workers or for closer defence co-operation, good luck. An argument can be made for all those things.
But there is NO ARGUMENT WHATEVER for rejoining the customs union while staying out of the EU. It would be like throwing away the burger and eating the napkin.

[Freddie New @freddienew]

Why the UK is financially broken, in a few simple numbers👇

We now pay £212 billion per year on on 'illness-related inactivity'. This is about 70 % of the ENTIRE INCOME TAX TAKE of the government.

So 70p of every pound you pay in tax goes not to nurses, teachers, doctors, schools, or to fixing potholes… but towards paying this bill. Towards paying people not to work.

It gets worse.

On top of this, the government will spend £111.2 billion this year just on servicing our national debt. On interest payments, not reducing the principal owed.

What does this mean?

That every single penny you have to pay in income tax is spent either on enabling people not to work, or on paying interest.

Not one single penny you pay goes on the things you might expect to pay tax for – on the police, on schooling, on healthcare, education, or defence. And remember, this is with the highest tax burden since the Second World War.

The system is running on fumes. Something has to give.

[John M. Brimacombe @skylander2000]

@united At least a 30 minute delay while you reopen our closed up aircraft and transfer our pilots to another flight. Robbing Peter to pay Paul. Not impressive.

[U.S. Senator John Fetterman @SenFettermanPA]

It’s uncharted but it was a choice.

I’ll never vote to shut our government down or for this mass food insecurity.

We need to end this chaos, reopen, and honor our solemn responsibilities.

[Glen Sturtevant @GlenSturtevant]

Five years ago, Virginians voted 2-to-1 to end gerrymandering. We created an independent Redistricting Commission so voters, not politicians, pick their representatives.

Now, with early voting open since September 19 and 800,000 ballots already cast, Virginia Democrats are trying to repeal that reform in a special session that wasn’t even called for redistricting.

The Virginia Constitution requires an intervening election before lawmakers can change it. That way, voters know where their delegates stand and can hold them accountable.

Trying to rewrite the Constitution while people are literally voting breaks that safeguard. We’re going to stop it and keep the power where it belongs: with Virginians, not Democrat politicians.

[John M. Brimacombe @skylander2000]

@openphone Having difficulty logging into to my account. Not getting emails with login code and not going to junk.

[Lord Ashcroft @LordAshcroft]

For every retweet of this post, I will donate £1 to the @VC_and_GC_Assoc up to £50,000.
Time is running out following @I_W_M’s decision to close the Lord Ashcroft Gallery.
Visit while you still can, to honour the bravery of those who risked so much to protect our great nation.

[Annabel Denham @AnnabelDenham1]

The problem for Rayner is that ordinary people are constantly hammered for the tiniest “blunders”. Accidentally drive into a bus lane and no one will show you any mercy. That’s the system our politicians built. So when they bend the rules of course the public is furious.

[George Galloway @georgegalloway]

Having voted for infanticide tonight (by a huge majority) our parliament may later this week vote for assisted suicide in pods. This is today's Sodom and Gomorrah

[Dr. Calum Miller @DrCalumMiller]

BREAKING: Abortion has been legalised up to birth in the U.K.

This is unspeakably evil

As a doctor and a human being I will spend the rest of my life fighting against this barbarism

You should too

[Barendina Smedley @fugitiveink]

Does London's unique and much-loved Wallace Collection require a "transformational journey"? A "masterplan" for the 6-year long, massive overhaul was announced earlier this week. Here's why I have my doubts:
https://t.co/k6l4VTEriu

[The Reform Daily @ReformDaily_]

➡️ Quite a week for Keir - busy betraying British interests at every turn.

Only Reform UK will truly stand up for our country & put the British people first.

#ReformUK #BritainFirst #StarmerBetrayal