Chloe Slaney

Postdoc in Genetic Epidemiology @mrc_ieu @BristolUni ||
Inflammation in neurological/psychiatric conditions and cognition using large cohort and genetics data

[Chloe Slaney @slaney_chloe]

Commentary by @mendel_random and me on a paper suggesting the highly prevalent East Asian #ALDH2 null variant may substantially magnify adverse effects of maternal alcohol use during pregnancy on child development.
https://t.co/gUmPWieZZ2

@mrc_ieu @BristolUni @ACERjournal

[david_mf_evans @evans1_d]

I'm looking to hire a postdoctoral fellow in genetic epidemiology for a two year appointment. Please forward on to those who might be interested:

https://t.co/meGDK1AdQI

[Natsuhiko Kumasaka @natsuhiko83]

I'm ready to present my poster at ASHG 2025 (Board 9173F) See you all next week!

[Nicholas Fabiano, MD @NTFabiano]

Tylenol use during pregnancy is associated with autism.

Tylenol use during pregnancy does not cause autism.

[Jon Douglas @atranscendedman]

Netherlands study of 55,000 adults found higher inflammation (CRP) linked to more negative mood, anxiety, and slower thinking.

Genetic data also suggest CRP and GlycA may play a causal role in negative affect.

https://t.co/L8AXTaVF0l

[Chloe Slaney @slaney_chloe]

PsyPost article on our recent paper finding associations between inflammation and depression, anxiety, cognition using non-genetic and genetic analyses in the @LifelinesNL Cohort.

Fantastic collaboration with @giollabhui @golam_khandaker Catharina Hartman, and many others!

[PsyPost.org @PsyPost]

New research using data from over 55,000 people has found that low-grade inflammation is associated with symptoms of depression, anxiety, and impaired memory. The results offer evidence that immune system activity may play a causal role in mental health. https://t.co/BOT6yt9yMs

[Chloe Slaney @slaney_chloe]

@mendel_random @mrc_ieu @BristolUni @ACERjournal We provide context for this study, highlight what we think is its critical finding and key questions that still need to be addressed, before considering the potentially serious public health implications of this work.

[Chloe Slaney @slaney_chloe]

Commentary by @mendel_random and me on a paper suggesting the highly prevalent East Asian #ALDH2 null variant may substantially magnify adverse effects of maternal alcohol use during pregnancy on child development.
https://t.co/gUmPWieZZ2

@mrc_ieu @BristolUni @ACERjournal

[Chloe Slaney @slaney_chloe]

Really enjoyed attending #ESHG - fantastic speakers presenting on a range of fascinating topics; hope to go again next year! 🧬

[Alex Kwong @asfkwong]

New paper by super @poppyzenzi in Nature Mental Health looks at network temperature 🌡️, a new parameter for examining stability of depression symptoms across adolescence.

Thanks to @CO90s @CLScohorts #ABCD @The_MRC @wellcometrust

Paper: https://t.co/0Zm0dMyjaO

Thread ⬇️

[Andrew McIntosh @mcintosh2001]

Many thanks to all of the collaborators and funders (esp @wellcometrust & @UKRI_News) who made this DNA methylome-wide study of antidepressant exposure possible https://t.co/AhRBy24q12

[Louise Arseneault @L_Arseneault]

🔎The Atlas of Longitudinal Datasets is open for use! Filter, compare, save and explore your way through over 1,600 datasets from around the world, with even more to come! Find the #AtlasLongitudinalDatasets here: https://t.co/3VNffv5K7S

@wellcometrust #longitudinaldatasets

[george davey smith @mendel_random]

A week left to apply for Senior Research Associate/Research Fellow posts with
@explodecomputer and me in sunny Bristol on genetic approaches to understanding phenotypic causation, including Mendelian randomization at @mrc_ieu https://t.co/CQ5iw20NEX

[Marios Georgakis @MariosGeorgakis]

Genetics of psychiatric disease enters a completely new level🧬🧠

Massive trans-ancestry GWASs for:

1⃣depression: 690K cases & 4.3M controls❗️
👉635 loci
👉6% of liability explained

2⃣bipolar disorder: 158K cases & 2.8M controls❗️
👉298 loci
👉up to 9% of liability explained

[European Society of Human Genetics (ESHG) @eshgsociety]

One more week until the abstract submission deadline for #eshg2025 #hybridconference! Do not forget to submit your abstract until Thursday, January 30, 2025, 23.59 h CET. All information can be found on our website:
https://t.co/26f98JviOZ
#genetics #genomes

[Chloe Slaney @slaney_chloe]

🙌A fantastic postdoc opportunity with George Davey Smith and Gibran Hemani in the @mrc_ieu‼️

I've thoroughly enjoyed working with George and Gib over the past few years and highly recommend this position to anyone interested in genetic epidemiology/MR!

[george davey smith @mendel_random]

Join Gib Hemani and my MR programme @mrc_ieu IEU,
Details in the links below

[UK Biobank @uk_biobank]

Today we’re launching the world’s most comprehensive study of proteins circulating in our bodies, which will transform research into new medical tests, drugs and treatments.

Discover more: https://t.co/o8t2yuknLv

[Marios Georgakis @MariosGeorgakis]

Our GWAS meta-analysis on the genomic architecture of 40 circulating cytokines in 75,000 individuals is now out @CommsBio 🧬❗️

A short thread about the topline findings🧵

[Eric Topol @EricTopol]

Digitizing the human proteome in >53,000 individuals with 15-year follow-up and, with machine learning, unraveling nearly 500 disease-causing proteins
https://t.co/VsYD6vG07R @CellCellPress

[Lifelines @LifelinesNL]

🧠How our genes link thinking skills & mental health
New Lifelines research by @slaney_chloe shows: Better thinking skills may reduce negative emotions & depression, genes for negative & positive emotions are distinct. Closer to better treatments! https://t.co/CWyo3SKk82

[Abbas Dehghan @Abbasdehghan]

Join Us for an Online Course

Advances in Dementia Research: Molecular Discovery, Neuroimaging & Prevention

📅5–7 Feb 2025

For PhD students, postdocs, & researchers in population & data sciences.

Register: https://t.co/zpzGWFu2pZ

Please RT!
@ImperialSPH @ImperialMed @UKDRI