We are beyond thrilled to announce the results from our research collaboration with @CerevelTx!
Today we are sharing the preprint of "Neuroimmune Cortical Organoids Overexpressing C4A Exhibit Multiple Schizophrenia Endophenotypes"
https://t.co/nvHgF59vzC
Hey Sci-Twitter-sphere! We are looking 4U. Interested in new genetic & physiol. tricks to get at cholinergics & cognitive decline? genetic regulation of psychosis? great lab in NIH intramural. Check it out & RT https://t.co/efZHFLlMnL Great toys, challenging questions. join us!
Exciting work from the @rajutomer lab demonstrating a new in vitro model system to study neuron networks in the context of Schizophrenia @NatureComms. Grateful for the opportunity to contribute to this project!
Extremely happy to see more than 3 years’ work has paid off. Special thanks to my supervisors @SchubiNeuro and @naelnadif who have been there supporting me throughout the ups and downs of the Ph.D. journey and also trusting me to try my own ideas. https://t.co/QRuprm1EOX
New paper from the lab!
We developed a novel human organoid that periodically forms somite-like structures. The spheroid of human iPS cells elongates and starts forming pairs of somites according to the segmentation clock.
https://t.co/fR2gLrG8XR
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Our single-cell atlas of brain organoid development is on bioRxiv today! This was a huge labor of love with my co-lead author @uzquiano_a and many others. We sequenced over 600K cells from brain organoids across time, and asked what they could teach us. https://t.co/JJ7kZ6KSaD
Happy to share our spatial analysis of human organoids! Fun to "see" organoid structure and cell types develop with multiplexed imaging + single-cell genomics! Great collab with @GrayCampLab@lucaspelkmans! Step towards virtual #Organoids, and exciting tools for phenotyping! 1/2
EMC10 reduction in human neurons and adult mouse brain rescues cellular and behavioral deficits linked to 22q11.2 deletion https://t.co/yWcoP7zPbA #biorxiv_neursci
finally out @NatureBiotech: cell2location tool for integration of single cell & spatial transcriptomics! Tons of new work showing that we can resolve fine cell types in spatial RNAseq & comprehensively map tissues. With @OliverStegle, proud of @vitaliikl👇https://t.co/vBTdZykbH6
Today Aaron and I are excited to announce Kana https://t.co/b9k1HYgCnk, an app to perform #SingleCell RNA-seq analysis in the browser. Yes you read that right, the calculations are performed client-side, by your browser, on your laptop! #webassembly
Want to analyze your data?🧵
I am excited to share a new study led by Shachar Givon & @MatanSamina w/ Ohad Ben Shahar: Goldfish can learn to navigate a small robotic vehicle on land. We trained goldfish to drive a wheeled platform that reacts to the fish’s movement (https://t.co/ZR59Hu9sib).
Scientists created a 3D model of vascularized spheroid 🔵 cells using an injection-molded microfluidic chip, and cocultured spheroids derived from induced #NeuralStemCells with perfusable blood 🩸 vessels.
https://t.co/cJpoeYKPYs
How do diverse neuronal identities emerge in self-pattenring cerebral organoids and what regulatory mechanisms are driving it? Find out in our new preprint lead by @SophieMJ_Jansen and @josch_f with @GrayCampLab and @zhisong_he https://t.co/NYgMbkFZYY
We are proud to share our paper with a comprehensive single cell RNA-seq, ATAC-seq and spatial atlas of the developing mouse neocortex, led by @DanielaJDiBella from the @ArlottaLab and @ehshabibi from Aviv Regev’s lab. https://t.co/LfqcEBqbYR