Exercise after a cancer diagnosis may improve survival.
A pooled analysis of 17,141 cancer survivors across 6 cohorts shows that post-diagnosis physical activity is associated with lower cancer mortality.
🏃♂️ Even small amounts of activity helped.
📊 Key findings
• Any activity vs none reduced cancer mortality in
– Bladder cancer: HR 0.67
– Endometrial cancer: HR 0.62
– Lung cancer: HR 0.56
• Meeting activity guidelines (≥7.5 MET-h/week) further improved survival.
• Doubling guidelines showed benefit in
– Oral cancer
– Rectal cancer
💡 Important insight
Patients who were inactive before diagnosis but became active after diagnosis had lower mortality in lung and rectal cancers.
🎯 Clinical message
Encouraging physical activity after cancer diagnosis may improve survival across multiple tumor types.
Exercise is not just supportive care.
It may be prognostic therapy.
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Tamoxifen works in both luminal subtypes, but the timing of benefit differs. In luminal B, the gain is early and clear. In luminal A, the early difference is modest, and the real protective effect emerges after 10–15 years. Late recurrence is the reality we cannot ignore.
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