Mark Morin

I'm being me, you do you, I'll be me.

[Headquarters @HQNewsNow]

Here is a compilation of Trump completely passed out asleep on live television as he turns 80 today.

[Congresswoman Yassamin Ansari @RepYassAnsari]

The White House cover up of the Epstein Files is the most egregious, disturbing and corrupt in American history. It’s criminal.

Read this stunning new reporting from the @nytimes ⬇️

https://t.co/ne1D1161z1

[Albert Samaha @AlbertSamaha]

They showed Trump on the Jumbotron during the anthem. He got more boos than the Spurs.

[Pop Crave @PopCrave]

More footage of Donald Trump getting booed at Madison Square Garden.

[Afshine Emrani MD FACC @afshineemrani]

I'm a cardiologist. I've held dying hearts in my hands in the cath lab at 3 AM. And I need to tell you something that changes everything about how we prevent heart attacks.

For decades, the entire field was built on one target: lower LDL cholesterol. Statins save lives — that's settled science. But too many of my patients did everything right — took their statins, hit their numbers, lived clean — and still ended up on my table with a ruptured artery.

We were treating the smoke while the fire kept burning.
The fire is inflammation. And the evidence is now overwhelming.

The CANTOS trial proved it first — lowering inflammation independent of cholesterol reduced cardiac events. But the newer data is what keeps me up at night.

AI-enhanced CT angiography can now detect inflamed arteries by measuring changes in the fat surrounding your coronary vessels — the perivascular fat attenuation index. Higher inflammation in the fat around even one artery independently predicts cardiac death. When multiple arteries show inflammation, the risk multiplies dramatically — even in patients whose cholesterol looks perfect.

This isn't theoretical. This is measurable. Right now. On a scan you can get this month.

Low-dose colchicine — a drug that's been around for centuries for gout — is now FDA-approved specifically for reducing cardiovascular events. It works by quieting the inflammatory cascade that destabilizes the plaque sitting in your arteries. A pill that costs pennies is saving lives the statins couldn't reach.

And the next wave is already in Phase 3 trials. Ziltivekimab — an IL-6 inhibitor — targets the central inflammatory pathway driving atherosclerosis. Phase 2 data showed a 90% reduction in hsCRP. The ZEUS cardiovascular outcomes trial is enrolling now, with results expected late 2026 into 2027. If positive, anti-inflammatory therapy will become standard in managing heart disease alongside lipid-lowering. The era of inflammation-targeted cardiology is arriving.
But it goes deeper than drugs. AI is now predicting heart failure and cardiac events 5+ years before symptoms — integrating CT imaging, electronic health records, and genetic data with accuracy that jumps far beyond traditional risk calculators.

And polygenic risk scores — a simple genetic test that flags inherited cardiovascular risk — are now formally recognized as a risk-enhancing factor in the 2026 ACC/AHA guidelines. A single blood draw can reveal risk that's been silently building since birth. Decades before the first chest pain.

Here's what this means for you right now — today:
Ask your doctor for a high-sensitivity CRP test. It's cheap, routine, and measures the systemic inflammation that standard cholesterol panels completely miss. You can have perfect LDL and inflamed arteries that are quietly preparing to rupture.
If your hsCRP is elevated, discuss low-dose colchicine with your physician. It's FDA-approved for exactly this.
Push for a coronary CT angiography with AI plaque and inflammation analysis if you have risk factors. This isn't the stress test your parents got. This is 3D visualization of your actual arteries — with AI quantifying not just how much plaque you have, but what kind it is and whether the surrounding tissue is inflamed.
Consider polygenic risk score testing — especially with a family history of early heart disease. It's now guideline-supported.

And the foundation that never changes: move daily, eat real food, sleep 7-9 hours, manage stress, and know your numbers — ApoB, Lp(a), hsCRP, fasting insulin.
I left Iran as a child with nothing. I rebuilt everything in a country that gave me the freedom to become a physician. I've spent twenty years watching patients get second chances.

The ones who haunt me aren't the ones who died on my table. They're the ones who survived but never acted on what the science was telling them — years before the event that didn't have to happen.

You can have perfect cholesterol and still have a heart attack. Inflammation plus genetics can drive plaque rupture in arteries that look "fine" on a standard panel.
The myth that normal cholesterol means you're safe has cost more lives than I can count.

We now have the tools to detect the fire — not just the smoke. AI to see it. Genetics to predict it. Drugs to quiet it. And the ancient basics — movement, real food, sleep, purpose — to prevent it from starting.

Prevention is the new cure. And the science to make it real is no longer coming.
It's here.

[Brian Stelter @brianstelter]

Here's what the booing sounded like inside MSG when Trump was shown on the Jumbotron:

[Mark Morin @sparklemark101]

@Aupadrey You have a potbelly, what could you possibly know about dick and pussy?

[Wise Guy @WiseGuy32639663]

@k1rallik @kenpaquette Guess I shouldn't share this then.

Oh, well. Fuck Trump. Fuck CBS.
https://t.co/n3asqlJv6r

[Afshine Emrani MD FACC @afshineemrani]

I'm a cardiologist. I take 7 supplements every single day.
Walk into any pharmacy and you'll see a hundred bottles promising miracles. Most are marketing. Some are actively harmful.
But a small few actually work — backed by real science, confirmed in my own practice, and taken by me personally every morning and every night.
Here's the honest list.

[Mark Morin @sparklemark101]

@_dennis_system Ok....David Crosby.

[Mark Morin @sparklemark101]

@JordaneDeSade Is that a yes or a no?

[🤍permabulla🤍 @permabulla]

Video of Usha Vance and shooter Cole Allen together in 2017 resurfaces:

🎥 @NCNewsOnX

[Jon Cooper 🇺🇸 @joncoopertweets]

This photo should be on the front page of every single newspaper in America today.

[Mark Morin @sparklemark101]

@Daily_MailUS @robert_kroupa 18 is legal....

[Mark Morin @sparklemark101]

@BiscuitsJesus I smoked Hella weed on floor for D&C. I did some L one night on floor.....one of most memorable moments of my life.
.I'll never forget it. Enjoy yourself, ease into it. And have fun. Sphere is the best.

[Mark Morin @sparklemark101]

@mountaingrl_ Alcohol and nicotine and caffeine

[Andrew Barber @fakeshoredrive]

Every year on Q-Tip’s birthday, I am legally obligated to post the video of him needle dropping & looping up a beat on the spot that had both Kanye and No ID losing it

🐐 (📽️: @ItsTheCons)

[Mark Morin @sparklemark101]

@carlquintanilla Tell Kernan to be a real man and quit dying his hair.

[Pete Buttigieg @PeteButtigieg]

Watch my full interview on @SquawkCNBC from this morning: