sparrow songs

little birdie

[sparrow songs @sparrowsongs_]

the threads to hang by (a thread)

[Ulugbek S. Kamilov @prof_kamilov]

The purpose of a PhD isn’t to know everything. It’s to become extremely uncomfortable with people who think they do.

[sparrow songs @sparrowsongs_]

fucking love when claude runs grep -r on the login node over a file tree with 2.5+ million files it is explicitly not allowed to traverse. hehe i hate this fucking thing! MORON. BAD.

[sparrow songs @sparrowsongs_]

@pmarca i think this might be one of those situations where correlation ≠ causation idk just a thought man

[sparrow songs @sparrowsongs_]

just run your little claude paper through claude as a reviewer one time. one time bro. this shit is ridiculous.

[sparrow songs @sparrowsongs_]

douglas yao enrages me. asinine takes. "biology is squishy means its not hard and smart people dont do it" treating drug discovery like a 2000s tech bro. youre not special. knock it off, dipshit.

[sparrow songs @sparrowsongs_]

i want crystals. i want structural data. i want biophysical binding studies. i want off target assays. i want simulation data. i dont want fucking chatgpt drugs shipped off to in-vivo because claude said it sounded cool. someone has to stop the tech bros.

[sparrow songs @sparrowsongs_]

@NTallapragada @arvindtessel are you hiring frogs or?

[François Chollet @fchollet]

The true measure of a software engineer isn't their ability to write clever code. It's their ability to ruthlessly protect the codebase from unnecessary cleverness.

[sparrow songs @sparrowsongs_]

fwiw doudna was obviously referring to *chatbots* and novel, *independent* innovation. on which point she is *correct*. all you idiots talking about alphafold as a counterpoint are missing her point entirely lol

[Michael Baym @baym]

pretty wild that mathematics is so hard when there's only 97 ascii characters required to TeX any proof

[Michael Lin, MD PhD 🧬 @michaelzlin]

When I was a young PhD student I realized the difference between chemistry and biology training at the time as that the former was completely devoid of the concept of controls and variability. Chemists writing biology papers would do n=1 experiments, without confidence intervals or negative controls. (May be different now.)

History repeats now with CS bros expecting they can feed some omics data from one cultured cell line into their model and they will learn how all cells work.

[Michigan Research @UMichResearch]

A @UMichPharmacy team has created an open-access database of 50,000+ chemistry experiments, testing thousands of combinations of ingredients and conditions to better understand the reactions that form the essential building blocks of many medicines. https://t.co/bjKq85IsFm

[🧛🏻‍♀️🇪🇬 @NADIlNE]

hot girls love sudoku

[sparrow songs @sparrowsongs_]

this has to be a shitpost right...right???

[sparrow songs @sparrowsongs_]

for the love of god someone please vibecode a GUI for AMBER

[sparrow songs @sparrowsongs_]

I swear to god there is no better feeling on the planet than when the physical chemist explaining an experiment says “thats an excellent question, of all the questions you could ask, you thought of that”

[John B. Holbein @JohnHolbein1]

"We propose that the p-value be demoted from its threshold screening role and instead, treated continuously."

[sparrow songs @sparrowsongs_]

maybe I should start a podcast

[Julian @Asghoull]

gang r u even pure of heart