Kashi is synonymous with Dev Deepavali and this year as well, the celebrations have been grand. Equally gladdening is the august presence of diplomats from several nations, who have got a glimpse of India’s cultural vibrancy.
Chandrayaan-3 Mission:
'India🇮🇳,
I reached my destination
and you too!'
: Chandrayaan-3
Chandrayaan-3 has successfully
soft-landed on the moon 🌖!.
Congratulations, India🇮🇳!
#Chandrayaan_3#Ch3
Director K. Natraj, the director of Valli about who's the music director of Valli.
Come on @rajinikanth , you should not have mentioned on stage that Karthik Raja was the music director.
https://t.co/bozBqNa3tT
Make this your must read for the day.
You will thank me and curse me in the same breath.
Every week I sign off death summaries of young and middle-aged men with liver dysfunction, multiple organ failure and liver cancer due to alcohol use. Some of them drank heavily – almost 1000 to 1200 ml/day while others consumed alcohol modestly – from 200 to 400 ml/day.
Some of my patients felt cheated. They drank with their friends and most of their friends drank much more than them but they were still healthy and productive, while my patients were either on death bed or waiting for a liver transplant.
Which begs the question - Should you consume mild to moderate alcohol for its purported health benefits especially on the heart?
But before we answer that, let us see the [infamous] J-shaped curve that projected alcohol consumption as beneficial in 'moderate' quantities versus no drinking. The 'presumed benefits' of moderate drinking was first published in 1924 by Biologist Raymond Pearl. See here: https://t.co/6FoMj9PZ2N
In it, he concluded that the effect of alcohol use followed a J-shaped curve (see picture on left side given below), where to the left of the tipping point of the ‘J’ were non-drinkers who survived much lesser and to the right were those who drank more than modestly and had increased death rates. So, the key to increasing life was to drink "moderately."
But why where they surviving better with modest use of alcohol and not no-alcohol or heavy alcohol?
Further research found out that one particular type of heart disease reduced with alcohol use - called ischemic heart disease, which is a type of 'heart attack,' where the blood flow to heart reduces and people develop a poor 'heart-pump.' https://t.co/cH9LNlsju2
But why was heart health, especially ischemic heart health reducing with modest alcohol use?
Fast forward to 2023 - a study by a group of doctors from Massachusetts General Hospital (MGH) found that the reason was that alcohol promoted long-term reductions in stress signaling in the brain leading to happier/healthier heart. And this was shared and cited by so many news media and on social media https://t.co/kJljazrwbI
Proving the above study, very interestingly, another kickass study showed that "lower stress reduction" was happening even at the molecular and cellular level, which was manifested by a reduced microvascular dysfunction or MVD - where 'blood health' was improved with modest alcohol consumption. https://t.co/EtHTUAIaD7
So, all good right?
Sorry not really.
Now lets get on with some reality checks!
A large study showed that the favorable health benefits of modest alcohol use was because people with lower/modest consumption also had better and healthier lifestyle such as dietary patterns and physical activity. And when these were taken out of the equation, lower doses of alcohol increased heart disease risk which increased exponentially with increasing dose and duration. https://t.co/rXs68YvzqL
And it just keeps going on and on. More recent studies suggest that association of low-to-moderate alcohol consumption with the reduction in cardiovascular risk is a result of lifestyle changes and that any reduction in alcohol consumption is in fact beneficial in terms of general health. https://t.co/hCgzmwmyYY
And quite interestingly, in those with worse health outcomes with low or modest consumption, genetic profile also played a role. If you did not have good genes, any amount of alcohol was going to harm you. And the best way to protect yourself was to not consume alcohol at all, because even now, the “good” genes are not yet fully identified (and probably will never be because it does not matter in the big picture). So, everyone is at risk until proven otherwise. https://t.co/6SFLmfw2S2
While light/moderate drinkers lowered their risk for ischemic heart disease, the 2023 MGH study also showed that any amount of alcohol increased the risk of various cancers and hence increased chances of cancer-related death even when you have a “supposedly healthy heart.”
This was again proven in the magnanimous study published this year - a large systematic review and meta-analysis, the highest grade of quality for evidence generation in medical science that “Low-volume alcohol drinking was not associated with protection against death from all causes," and that it increased risk more in women than men. https://t.co/LXvUv9ULtc
But then there was this study that showed that people with modest alcohol use gained one whole year in their lifetime. Oh super! It’s time to be merry! Sorry to burst your bubble again, but the gain of one year by modest drinkers was erased by a two to fourfold increase in mouth and food-pipe (esophageal) cancer and that drinking beyond modest amount led to a large loss of life expectancy. https://t.co/vtrsPtysup
And to top it all off, like placing a rotten black cherry on top of alcohol connoisseurs’ happy cake, scientists again proved that any level of alcohol was unsafe because it increased risk of cancers like hell. They are making you feel happy and sad at the same time. Sadists! https://t.co/iee44IKFJ5 https://t.co/FqxVtVGpVc
Look at all these big medical mafia and pharma shill scientists trying to protect your health from something you love to do! Bad guys, no?
Now let us come to the picture on the right side.
See what that is all about?
Individuals who engaged in 15–20 min of simple physical activity per day experience a similar level of reduced mortality as portrayed by the “J-shape” of modest alcohol use. And see how that graph is going. The more you increase physical activity, the more your chances of living longer! And guess what, without the risk of cancer of course!
https://t.co/PgANJkJHeb
Hey, did I tell you what the MGH guys who recently discovered that stress reduction in brain with alcohol improved heart health also found out? Guess I did, but here it is again! While light/moderate drinkers lowered their risk for cardiovascular disease, the study also showed that any amount of alcohol increased the risk of cancer. Just like we discussed before and some more. https://t.co/1V2bFjOlFD
So, forget about the less is more with alcohol use; many alternative healthy lifestyle choices mean more is merrier.
So, ditch that alcohol drink and that cocktail and start with some good physical activity daily.
Just 20 minutes a day.
But the more the merrier.
And live a good long life.
Trust me, it’s worth it.
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@sandhyaravishan@DhivCM There was no concept of NRI in British India. And even if they can be considered for argument sake, they are not upon return to India and staying here over 182 days.
However what RG meant was someone with outside India view. NRI, IMO, is a wrong word
@firstpost How did you arrive at 3.91 billion ?
Read through the entire article but in vein.
Sounds like an impression count as a part of their promotion.
Me at 46:
- Overweight
- Facing 3 chronic diseases
- Depressed
- Balding
Me at 64:
- Healthy weight
- Living and thriving with no diseases
- Happy
- Full head of hair
Here are 5 steps I took to heal myself and age backwards without doctors, health insurance or medication: