Published today! We used targeted #MSKimpact tumor sequencing data to infer genetic ancestry and identify associated somatic features in ~50,000 patients. Lots of interesting methods and findings, but I will focus on one. 🧵 @MSKCancerCenter (1/10)
https://t.co/wdH1aMm6hX
Proud to share our work out today in @NatureGenet. With @srinipr4, @MFBerger1 and @BarryTaylorLab.
https://t.co/fyHjvxDbpe
We try to understand the extent to which cancers arising in patients with inherited pathogenic variants are actually mediated by the germline defect, 1/n
And check out the new portal that goes with this paper: https://t.co/bgWF0kbs7k! Think of it like @gnomad_project but for germline variation in cancer. It was a pleasure building this with @chaiband@srinipr4@MFBerger1@BarryTaylorLab and our usual posse @gaojj, Onur and Xiang
Following the departure of four stellar postdocs (@huzheng1, @caswell_jin, @seoaneja, Kasper Karlsson) who have launched independent careers in the past year, the Curtis Lab (https://t.co/WqFoOA8gPN) is recruiting postdocs and computational staff scientists.
Our (co-inventors @McLellan_Lab) COVID-19 vaccine (spike delivered by @moderna_tx's mRNA) was just injected into the 1st human in phase 1 trial, only 66 days after viral sequence release... a testament to rapid vaccine development for emerging diseases🦠💚
https://t.co/2DLZsdirAD