#TAMEtrial just published!
🩸 Does mild hypercapnia (50-55 mmHg) vs normocapnia (35-45 mmHg) improve outcomes in OHCAs admitted to the ICU?
🧠 Good neuro outcome at 6 mo:
43.5% (hypercapnia) vs 44.6% (normocapnia)
🔗 @NEJM https://t.co/2Fhskr76Ge
#CCR23#ResusTwitter#FOAMcc
#CCR23: In the TAME trial involving patients with coma after out-of-hospital cardiac arrest, a strategy targeting mild hypercapnia for 24 hours did not improve neurologic outcomes at 6 months as compared with targeted normocapnia. https://t.co/4ZxFzWUsno
https://t.co/v6JnHLkcZo
It is with great sadness and with the warmest memories we remember our friend and fellow researcher Professor Paolo Pelosi. Paolo was an essential member of the TTM-trial group from its start more than 15 years ago.