Najam Us Saqib

Structural IC @GeisingerHealth. alumnus @endeavorhlth @UofCincy | IM & CVD alum @WrightcenterGME @RossMedSchool @TempleUniv 🇺🇸🇵🇰🦉🦅

[Shahzeb Khan @ShahzebKhanMD]

✅Excited to receive NIH R01 award to study rapid/simultaneous initiation of GDMT in CKD

📌Usual practice is slow initiation which can take years. RAPID-CKD trial will see if rapid administration of GDMT in CKD is feasible, safe and effective

@JavedButler1 @f2harrell #TShafi

[PCRonline 🫀 @PCRonline]

My Toolkit 🧰⚙️🪛: Self-made steerable catheter to cross the aortic valve in severe aortic stenosis

🔗https://t.co/ZFpZV7gDb6

In this article, @Obisht, Won-Keun Kim and Robert R. Flieger describe a self-made steerable catheter system using a 6F EBU guide and the stiff back end of a 0.035″ wire, combined with a hydrophilic straight-end crossing wire, to facilitate crossing of severely stenotic or calcified native or prosthetic aortic valves during TAVI.

The technique is particularly useful in horizontal aortas, bicuspid valves, and massively calcified tricuspid or bioprosthetic valves, where the conventional technique repeatedly fails.

Reviewed by Moritz Seiffert

#interventionalcardiology #CardioEd #cardioX

[Shehbaz Sharif @CMShehbaz]

I congratulate President Donald Trump on his extraordinary efforts to pursue peace and for holding a very useful and productive telephone call earlier today, with the leaders of Saudi Arabia, Qatar, Turkiye, Egypt, the UAE, Jordan and Pakistan. Field Marshal Syed Asim Munir represented Pakistan in the telephone call and I greatly appreciate his tireless efforts during the entire process.The discussions provided a useful opportunity to exchange views on the current regional situation and how to move the ongoing peace efforts forward to bring lasting peace in the region. Pakistan will continue its peace efforts with utmost sincerity and we hope to host the next round of talks very soon.

[Jeffrey Wilson, MD @jl35wilsonMD]

Yeah this is bullshit. I have referred 3 Pts for Ross in the last 1-2mos. Anyone under 65 gets a big discussion from me, and anyone <55 I recommend mAVR or Ross primarily. This leaves aside the fact that there are a lot of unknowns about bAVR vs TAVR durability on index intervention vs 2nd/3rd intervention. Where is the discussion of CT surgeons recommending CABG when the SYNTAX in <32 and there is zero mortality benefit? Do surgeons consent patients and tell them there’s a 50% chance their SVGs will be included at 10yrs and 20% chance of SVG occlusion at 1 yr? Never. This conversation always biases against the proceduralist and never against the surgeon.

[Najam Us Saqib @structuralMD]

$7.8 BILLION….BILLION

[JAMA @JAMA_current]

US nonprofit hospitals spent $7.8 billion on management consultants from 2009 to 2023, but contracts were not associated with meaningful changes in finance, operations, or quality of care. 🧵

https://t.co/QQswMYxrG8

[Najam Us Saqib @structuralMD]

@ShaheerZ566 @mj_ricciardi @jlevismd @JRRosenbergMD @viali86 @EdwardsLifesci @EndeavorHlth Thank you!!! 🙏

[Najam Us Saqib @structuralMD]

🚀 Milestone moment!

Proud to share our first commercial Sapien M3 case following completion of enrollment in the ENCIRCLE trial.

A huge team effort bringing next-generation transcatheter mitral therapy to patients—excited for what’s ahead.

Grateful to an incredible multidisciplinary team who made this possible. 👏

#StructuralHeart #TAVR #MitralValve #Innovation #Cardiology

[Mark J Ricciardi MD @mj_ricciardi]

@najamsaqibMD @jlevismd @JRRosenbergMD @viali86 @EdwardsLifesci @EndeavorHlth One of the very first M3's in the country, the first Encircle Trial M3 in the region and now this - another first in the region @EndeavorHlth Cardiovascular Institute at Glenbrook

[American Heart Association @American_Heart]

The American Heart Association mourns the passing of the legendary cardiologist Eugene Braunwald, M.D., widely recognized as one of the most influential figures in the history of cardiovascular medicine. Over seven decades, his work reshaped the understanding and treatment of heart disease, leading many to call him the father of modern cardiology.

Braunwald was a lifelong contributor to the American Heart Association, helping advance its research and scientific mission, and was honored with some of the Association’s highest honors for his lasting influence on cardiovascular care and research. His influence extended well beyond his own discoveries, as generations of Association‑supported investigators, clinicians and academic leaders were trained by Braunwald or guided by the clinical trial standards and mentorship models he helped establish.

https://t.co/ieZuHYMyOP

[Najam Us Saqib @structuralMD]

A Provider Provides. A Physician Decides https://t.co/9kWtEVQmZN

[Najam Us Saqib @structuralMD]

❤️

[Dan Qayyum @DanQayyum]

https://t.co/Q3ZRsR9cfL

[Najam Us Saqib @structuralMD]

#pakistan
#notowar
#peace

Thank you! ❤️

[Shehbaz Sharif @CMShehbaz]

With the greatest humility, I am pleased to announce that the Islamic Republic of Iran and the United States of America, along with their allies, have agreed to an immediate ceasefire everywhere including Lebanon and elsewhere, EFFECTIVE IMMEDIATELY.
I warmly welcome the sagacious gesture and extend deepest gratitude to the leadership of both the countries and invite their delegations to Islamabad on Friday, 10th April 2026, to further negotiate for a conclusive agreement to settle all disputes.
Both parties have displayed remarkable wisdom and understanding and have remained constructively engaged in furthering the cause of peace and stability. We earnestly hope, that the ‘Islamabad Talks’ succeed in achieving sustainable peace and wish to share more good news in coming days!

@realDonaldTrump
@JDVance
@SecRubio
@SteveWitkoff
@SEPeaceMissions
@drpezeshkian
@mb_ghalibaf
@araghchi

[Pakistan Defence🇵🇰 @PakDefence_]

Noble peace prize for Field Marshal Syed Asim Munir

[Najam Us Saqib @structuralMD]

@GovtofPakistan thank you

@world you owe one!!!

Hopefully this leads to lasting peace in this world. No more wars!

[Hassan Abbasian @HassanAbbasian]

Arguably best Chief Pakistan has ever had — Field Marshal Asim Munir. 🔥🇵🇰

[Jeffrey Marbach @JAMarbach]

Criticism of STEMI-DTU is revisionist. Biologically grounded strategy supported by years of preclinical work. We cannot claim to value innovation, then ridicule a rigorously tested hypothesis because the trial was neutral. Hypocrisy deserves to be called out. @NavinKapur4

[Najam Us Saqib @structuralMD]

Precise and wise arguments! 👏🏻👏🏻👏🏻

[Albert Lin, MD @AlbertLinMD1]

CHAMPION-AF: My thoughts, especially in the context of CLOSURE-AF.
A quick summary of the trial and main findings:
1. 3000 patients randomized in 1:1 DOAC vs Watchman Fix, mean age 71, avg CV2 3.5.
2. Primary efficacy endpoint composite of CVD, stroke/SE

[C. Michael Gibson MD @CMichaelGibson]

Dr. Saibal Kar and Dr. C. Michael Gibson discuss the CHAMPION-AF trial: Left atrial appendage closure with the WATCHMAN FLX device was non-inferior to DOACs for the composite of CV death, stroke, or systemic embolism among patients with non-valvular AFib. #ACC26 Watch video here: https://t.co/r8H7XUAeAz

[Najam Us Saqib @structuralMD]

Amazing explanation by @ihtanboga

So much to learn on biostat front. Thank you for such explanation.

[I.H.Tanboga, MD, PhD @ihtanboga]

Study conclusion: Angiography guided PCI was associated with significantly higher risk for MACE, However, IVI-guided PCI had comparable risk with CABG in DM patients.

But there's a methodological concern hiding in the study design that the authors didn't discuss:
Immortal time bias.

1/

[Najam Us Saqib @structuralMD]

History, though harsh, teaches us many truths. However, failing to comprehend it only forces us to learn the hard way.

[Hany Ragy @Hragy]

Anyone who worked as an interventional cardiologist before the introduction of Stents , knows that the current direction to promote DCB as stent free PCI world will fail.
What we really need to know is if we can use DCB when and where we do not want to put DES,like distal LAD.

[Omar Khalique @OKhaliqueMD]

IVL in MAC - it's here

@purviparwani @onco_cardiology @iamritu

https://t.co/Z8TwELW3QU