Tadasu Nozaki

Chromosome researcher @UMassAmherst. Tweets in English and Japanese (時々英語、時々日本語) #LiveCell #SingleMolecule #Meiosis #Chromatin #pairing

[Tadasu Nozaki @tadasu443]

I launched my lab at @UMassAmherst this fall. We study the mechanisms of meiotic homolog pairing using advanced live‑cell and super‑resolution imaging. Currently in budding yeast, with plans to expand to other eukaryotes. #Chromosome #Meiosis #Mitosis
https://t.co/BPvQghmCx2

[Anders Sejr Hansen @Anders_S_Hansen]

(1/16) Our 3-lab collab (Mirny & Zechner) led by Harvey, Henrik & Jack is out:

Q: How do enhancers & promoters interact in space (contact vs. action-at-a-distance) and time (stable vs. transient)?

A: Transient E-P contact (~25-42 nm lasting ~10-20 sec): https://t.co/wyPaLyvR8A

[Tadasu Nozaki @tadasu443]

@IshiguroL パスポートをとりに戻られていたとは知りませんでした。無事に帰国されますように。

[Yuki Shindo @_yuki_shindo]

My lab @UTD_Biology is hiring a research technician who studies the mechanisms of nuclear transport and organization using the Drosophila brain as a model system! https://t.co/qlz0dZQZ9f

[ISHIGURO Lab @IshiguroL]

MEIOSIN retains an intrinsic STRA8-independent activity that drives meiotic entry across vertebrate evolution https://t.co/MPaG4knnHl This paper will be published from Genes Dev

[Nature Methods @naturemethods]

SeeDB-Live is a tissue-clearing approach for live tissue slices or brains, improving image quality while having minimal effects on electrophysiological properties of neurons. @TakeshiImaiLab @Shigenori774

https://t.co/3mzllLyuW4

[Joe Nassour @NassourJoe]

Our review is now live @TrendsCellBio. We discuss how the DNA repair pathways c-NHEJ, MMEJ, and HR intersect at mammalian telomeres and the consequences for chromosomal instability. https://t.co/TTstou5YZW

[Anders Sejr Hansen @Anders_S_Hansen]

Detecting plectonemes using RCMC https://t.co/DAwF4VRGXN

[Matteo Mazzocca @mazzocca_matteo]

Our chromatin dynamics paper is now in @NatureSMB with important updates. We tracked chromatin in additional cell lines (5 overall), from the shortest timescales accessible today, over 6-7 orders of magnitude in time (MINFLUX + camera-based tracking)
https://t.co/nMU4k0V6kS

[Katie Galloway @GallowayLabMIT]

So you want to engineer your hiPSCs, but targeting DNA payloads requires multiple slow, inefficient steps for each construct. What if we could accomplish multi-site integration seamlessly? Come hear about STRAIGHT-IN Dual now out at Nature Biomedical Engineering! 🧵

Link at end!

[nature @Nature]

Geneticist J. Craig Venter, best known for his role in sequencing the human genome, has died aged 79.

He spoke to Nature in 2023 about AI, sequencing the ocean – and why he had no plans to stop working.

https://t.co/FYq5jbMpxa

[Arc Institute @arcinstitute]

Today in @Nature, the @genophoria & Vijay Ramani labs reveal that our picture of how nucleosomes regulate DNA accessibility has been too simple. They find that over 85% of nucleosomes in mammalian cells are structurally distorted, with DNA partially accessible even while wrapped.

[Keishi Shintomi @ShintomiK]

Excited to share our new paper! Using a tunable frog egg extract system, we show that nucleosome density and histone dynamics actively shape mitotic chromosome architecture. https://t.co/0OVQGxR5cO

[Center for Physical Genomics and Engineering @PhysGenCenter]

Last week's fantastic seminar by Prof. Harmit Malik, "Genetic Conflicts Drive The Unexpected Rapid Evolution Of Essential Chromatin Proteins", can now be viewed on CPGE's YouTube channel!

#chromatin #genomics #evolution #northwestern #genomics #proteins

https://t.co/trFeWYYJiV

[Ichiro Hiratani @IchiroHiratani]

My latest perspective on the regulation of DNA replication and 3D genome organization in early mouse embryogenesis, including why four scRepli-seq studies reached slightly different interpretations. https://t.co/9LV2jdbQ0R

[National Academy of Sciences @theNASciences]

Congratulations Alice Y. Cheung of @UMassAmherst, newly inducted #NASmember! #NAS163 #biochemistry #plantbiology

[Naoya Takahashi @zuNaoya]

I'm incredibly thrilled to share that our project on competitive robot table tennis, Ace, has been published today on the cover of @Nature

[Takashi Akera @TakashiAkeraLab]

I’m tenured! Thank you so much to everyone here, mentors, lab mates, colleagues, and the meiosis/centromere community for your support. This achievement was made possible by all the hard work by my amazing lab members over the past 6 years!🥳

[Cell @CellCellPress]

In the latest issue! A recipe for chaos: Extrachromosomal DNA and the hallmarks of cancer https://t.co/4eYQTutaJL

[Anthropic @AnthropicAI]

Our Long-Term Benefit Trust has appointed Vas Narasimhan to Anthropic's Board of Directors.

Vas brings more than two decades of experience in medicine and global health, including as CEO of Novartis.

Read more: https://t.co/DSvtZUTone