takis

[Danny (Dennis) Citrinowicz ,داني سيترينوفيتش @citrinowicz]

One of the great ironies of this war is that the very person who built his career around the idea of toppling the Iranian regime are now witnessing the opposite outcome.

Instead of emerging weakened or isolated, the regime appears more entrenched and, in some respects, more diplomatically relevant than before. The assumption of the Israeli pm that military pressure would trigger regime collapse, pave the way for regional normalization, and allow Israel and the Gulf states to bypass the Palestinian issue has largely failed to materialize.

At the same time, the United States, under what many Israelis viewed as one of the most pro-Israel administrations in recent years has shown little appetite for a long-term confrontation with Iran. Washington's priority increasingly appears to be de-escalation and some form of accommodation with Tehran rather than another Middle Eastern military adventure.

The result is a strategic reality very different from what BB imagine in his worse dreams. Normalization with Saudi Arabia looks more distant than before, the Palestinian issue remains unavoidable, and Iran's leadership sees further evidence that it is not going anywhere. In fact, Tehran is now deepening its engagement with regional actors, including Saudi Arabia itself.

This outcome raises difficult questions about the assumptions that guided the campaign and whether key decision-makers relied on assessments that were disconnected from the political realities of the region.

Towards the end of his political career Netanyahu sees everything that he build collapsing, and the possibility of increased friction with President Trump is mounting.

On February 28, Netanyahu probably thought he was witnessing the fulfillment of his life's work: the United States and Israel going to war against Iran.

Months later, that moment increasingly looks less like the culmination of a grand strategy and more like the point at which it unraveled.

What was supposed to remake the Middle East turned into a house of cards, as the assumptions underpinning the strategy collapsed one by one. The result was not regime change, not regional realignment, and not a breakthrough in normalization, but a stark demonstration of how detached the strategy had become from reality and a real risl that his relationship with the US would deteriorate to a level not seen before

[Danny (Dennis) Citrinowicz ,داني سيترينوفيتش @citrinowicz]

My Analysis @ACMideast regarding the agreement between US and Iran:

The end not just of war, but also of a strategic assumption about regime change in Iran

A US-Iran agreement will likely bring to an end, at least for the foreseeable future, the long-standing expectation in parts of Jerusalem and Washington that sustained pressure could lead to regime change in Tehran.

From Israel’s perspective, the conditions appeared unusually favorable for such change. Iran was confronting significant internal and external pressures, while Israel operated with unprecedented military freedom and the support of the world’s most powerful military ally.

But the announced agreement suggests a fundamental reality: The campaign that many hoped would weaken or even destabilize the Islamic Republic will instead conclude with the regime intact, strengthened, and formally engaged by the United States.

This would not represent a tactical setback. It would amount to the collapse of a broader strategic assumption: that coordinated American and Israeli pressure could generate conditions conducive to fundamental political change inside Iran.

Instead, the likely outcome is the opposite. The Iranian leadership could emerge from its most significant test in decades having demonstrated resilience, retained control, and shown a willingness to absorb substantial costs while preserving core regime interests. Such an outcome is likely to reinforce the confidence of the ruling elite rather than weaken it.

Moreover, Tehran stands to gain several important advantages: economic relief, renewed diplomatic legitimacy through engagement with Washington, and a perception that American leverage over Iran has diminished relative to what it was at the outset of the cris

Assuming maritime routes remain open and regional escalation is contained, negotiations will inevitably return to the nuclear file. It is already apparent that neither Iran’s missile program nor its network of regional partners is likely to be central to any near-term agreement. Nonetheless, unresolved issues, particularly those related to Lebanon and regional security arrangements, could still complicate implementation

The broader strategic consequence is that today’s decision reduces the likelihood of renewed large-scale conflict in the immediate future while simultaneously strengthening the Iranian regime’s regional and international position. It also risks increasing Israel’s diplomatic isolation on the Iran issue, particularly as Gulf Arab states increasingly prioritize de-escalation, economic stability, and a durable ceasefire over continued confrontation.

From Tehran’s perspective, such a result would constitute a significant strategic achievement. Iran would preserve critical strategic capabilities, maintain its influence across multiple theaters—including the increasingly interconnected Lebanese and Iranian fronts—and secure meaningful economic breathing space. Just as importantly, it would retain its ability to threaten vital maritime chokepoints and global energy flows, a source of leverage that remains central to its regional strategy.

The broader lesson is that operational success does not automatically translate into strategic success. Military pressure imposed significant costs on Iran, but it did not produce the political transformation that some anticipated. Ultimately, Iran’s ability to impose risks on global markets, combined with the practical limitations of eliminating or removing its nuclear infrastructure through force alone, pushed all sides toward negotiation. 

The result is an agreement that underscores a growing divergence between Washington and Jerusalem. While Israel may continue to view such an arrangement with deep skepticism, its ability to prevent the outcome appears increasingly limited. For the United States, the agreement may represent a pathway to regional stabilization. For Israel, it may be seen as confirmation that military achievements alone were insufficient to achieve the broader strategic objectives that guided the campaign from the outset.

#IranWar‌

[takis @takisk]

@emmitonair true

[Afshine Emrani MD FACC @afshineemrani]

I'm a cardiologist. If you've ever been told "your calcium score is zero — you're fine," I need you to read this carefully.

A new study just changed how I think about the most popular heart scan in preventive cardiology.

The NATURE-CT study — published in the Journal of Cardiovascular Computed Tomography in 2026 — tracked 205 low-risk, untreated adults with two detailed coronary CT angiograms roughly five years apart. No diabetes. No statins. No prior heart attacks. Average LDL around 112 mg/dL — what most labs still call "normal." Over half had a calcium score of exactly zero at baseline.

What happened over five years with no treatment:

Total plaque volume roughly doubled. From about 30 cubic millimeters to 59.

And here's the finding that should change how every patient and every physician thinks about the calcium score:

Nearly all the growth was non-calcified soft plaque — the lipid-rich, inflamed kind most linked to heart attacks. Soft plaque grew from 27.5 to 53.5 cubic millimeters. Calcified plaque barely moved — from 0.3 to 3.2.

The most dangerous subtype — low-attenuation plaque, the very soft, rupture-prone lesions that cause sudden cardiac events — was present in 9% of patients at baseline. Five years later: 23%. More than doubled.

Even among patients with a true zero calcium score at baseline, non-calcified plaque was often already present and grew substantially. Silently. Without symptoms.

Let me explain why this matters so much — because I've been ordering calcium scores for twenty years and I need you to understand what they can and cannot tell you.

A calcium score measures calcified plaque. Calcium in your arteries is essentially scar tissue — the healed residue of old inflammation. Think of it as a smoke detector that only detects fires that already burned out.

A zero score means: no old scarring detected. It predicts very low short-term event risk — typically a "warranty period" of 5-15 years depending on your other risk factors. That's genuinely reassuring and I still order this test regularly.

But a zero score does NOT mean zero plaque.

It means the scan is blind to the plaque that's most likely to kill you — the soft, active, lipid-rich plaque that's growing right now inside your artery walls. The plaque that ruptures without warning and causes the heart attack nobody saw coming.

This is why I've had patients on my cath lab table who said: "But my calcium score was zero two years ago."

It was zero. And the soft plaque that was already there — invisible to the calcium scan — kept growing until it ruptured.

A coronary CT angiogram with AI-enhanced plaque composition analysis is the difference between seeing old scars and seeing the active fire. It visualizes your arteries in 3D with contrast, quantifies total plaque burden, and — critically — tells me how much is soft and dangerous versus calcified and stable.

The NATURE-CT study used exactly this technology — Cleerly's AI plaque analysis — and it revealed what the calcium score alone would have completely missed: a near-doubling of dangerous plaque in "healthy" people with "normal" cholesterol over just five years.

Here's what this means for you:

If your calcium score is zero — celebrate it. It's genuinely good news. You have time. Use that time wisely.

Do not interpret it as "I'm fine forever." Plaque is building. In most adults over 40, it's already there — just in a form the calcium scan can't see.

Know your ApoB. This counts every atherogenic particle penetrating your artery walls. LDL of 112 — the average in this study — looks "normal" on a standard panel. But those particles were building plaque year after year in every single patient tracked. ApoB tells you the real particle burden. Most people have never had it checked.

Know your Lp(a). Test it once in your lifetime. 1 in 5 Americans are elevated. Completely genetic. Triples risk independently. Diet and exercise cannot lower it.

If you have risk factors — family history, elevated ApoB or Lp(a), metabolic syndrome, autoimmune disease — push for a full coronary CT angiogram with plaque analysis, not just a calcium score. The difference is the difference between seeing the scars and seeing the disease.

If soft plaque is found early, we can stabilize it. Statins don't just lower LDL — they stabilize plaque, making soft lesions harder and less likely to rupture. PCSK9 inhibitors drive LDL even lower. Lifestyle — Mediterranean diet, resistance training, sleep, stress management — reduces the inflammation that makes plaque vulnerable.

The goal of prevention isn't perfection. It's slowing the slope so dramatically that you never have an event. And the NATURE-CT data proves that the slope is steeper than we thought — even in people who look "low-risk" by every standard measure.

I've written on this platform about inflammation as the fire behind heart disease. About AI detecting inflamed arteries years before symptoms. About advanced lipid testing that catches what standard panels miss. This study ties all of it together into one devastating conclusion:

The standard playbook — check calcium score, if zero you're fine, see you in five years — is not enough.

It was never enough.

We were looking for old fires and missing the ones still burning.

Zero calcium buys you time. It buys you peace of mind. But what you do with that time — the ApoB you check, the lifestyle you build, the advanced imaging you pursue when risk factors warrant it — is what determines whether you stay healthy or become one of the patients on my table who says "but my score was zero."

Prevention works best before the calcium rises. Before the symptoms appear. Before the event that didn't have to happen.

Measure what matters. Act early. Stay ahead.

Your arteries will thank you for decades.

[Survival Instinct @SurvivalInstint]

Armlock instead of rear naked

[Richard @PGC1a_RB]

Retatrutide blocks Epithalon true, rether full, effects

Epitalon lowers RHR and raises HRV

Reta blocks that by doing the inverse, due to glucagon receptor activation, raising RHR, and lowering HRV

Retatrutide's tonic glucagon receptor activation does disrupt the normal pulsatile glucagon-receptor timing machinery

Whether you accept the trade-off of Epitalon not working as well due to combining it with Reta, is up to you

[The Hood Therapist @OhhMar24]

Jalen Brunson taking the pay cut to come to New York, getting his friends on the team and actually winning the Championship. One of the most gangster stories in NBA history

[Timeless Sports @timelesssports_]

2016 NCAA Champions.

2026 NBA Champions.

[DividendMillennial @DividendMil]

If you had bet $100 on the Knicks at the lowest point of each of their 4 Finals comeback wins and rolled the winnings into the next game…

$100 would have turned into roughly $24.4 million.

Game 1: Down 16
Game 2: Down 18
Game 4: Down 29
Game 5: Down 15

That’s how ridiculous this Finals run was.

The Knicks didn’t just win a championship. They pulled off a sequence of comebacks that may never be replicated. 🏆🍾💰

[GlobalWrestOrder @GlobalWresOrder]

The Greatest phenom in USA Wrestling history Aaron PICO (USA) makes a successful return to wrestling after 10 years 🔥🙌

Pico gets the 12-1 TF win over NCAA Finalist🥈Lance PALMER (USA) and looks as good as ever.

[Spencer Hakimian @SpencerHakimian]

Put it in the Twitter hall of fame

[Aakash Gupta @aakashgupta]

Google hid a fully working flight simulator inside Google Earth back in 2007 and never told anyone.

You unlocked it with a secret keystroke: Ctrl+Alt+A. No menu, no announcement. One user stumbled onto it, the combo spread, and it got popular enough that Google made it official the next year. Two planes, an F-16 and a Cirrus SR22, flying over real satellite imagery of the entire planet.

Then it stayed locked inside the downloadable desktop app for 18 years. The browser version was a stripped-down viewer that couldn't run it. Today that changed.

Here is the part that makes it impressive. A flight simulator is the single hardest thing you can ask a 3D map to do. Panning is easy, the software has all the time it wants to load the terrain ahead of you. Flying low and fast strips that away, forcing it to fetch, decompress, and render the world faster than you are crossing it. The hardest possible job for every part of the system at once.

So "just for fun" is carrying a lot of weight in that sentence. Getting this to run in a browser tab is the cleanest proof that the web version finally matches what used to need a desktop app.

The toy is the benchmark.

[Adam Ryan 🤝 @AdamRy_n]

Aldon Smith passed away this weekend. Most people are talking about his incredible ability, potential, and performance as a football player.

Even though that is all true. He was so much more than that. He was a great friend and his kindness changed my life forever.

I met Aldon our freshman year at Mizzou. He was redshirted and relatively unknown as an athlete. His giveaway was the biggest hands you'll ever see and his ability to dunk at 250lbs, but his size in many ways didn't match his personality. He was relatively quiet and in most scenarios would try to shrink into the room vs stand out in it.

Over the course of the next year, we became close. We were very different people, from different places, but we both connected on the feeling of being a bit lost in the beginnings of adulthood. That year, I never really thought about him as a football player. He was just this gentle giant who loved to play video games and talk about life.

His sophmore year he broke the single season sack record at Mizzou, became an All American, and his life changed forever.

He became a celebrity on campus. He became a household name in Missouri. He became a top NFL draft prospect.

I remember how crazy his life became, and how quickly. ESPN doing interviews. Fancy cars being "loaned" to him. And people everywhere inserting themselves into his life.

Despite the craziness, my friend was always a text away.

My junior of college, I decided to take my first stab at entrepreneurship. I wanted to launch a chapter of Camp Kesem.

Kesem is a summer camp for children whose parents have been affected by cancer. The camp would be totally free and be a chance for a kid to experience the magic of being a kid again. As a son of a breast cancer survivor the idea of being able to create this camp in Missouri meant the world to me.

The Livestrong Foundation was hosting a nation wide contest to win $10,000 as seed capital to get started. To win, you had to have the most votes.

I tried really freaking hard to win that competition. I was going up against some really influential people at huge schools. As a somewhat awkward kid in Columbia, MO I had no chance.

So I asked my friend Aldon for a favor. I asked him if he would help me out and promote the link to vote.

He did more than just posting about Kesem on Facebook, skyrocketing us into the top place in the country. He kept supporting me the next 3 years while I was working on building Kesem.

He showed up to have fun with the kids. He helped me fundraise. He helped me get Kesem to become an official organization sponsored by the NFLPA so he could publicly endorse us as as a player.

Since then Torry Holt, Larry Fitzegerald, and many others have supported Kesem. But Aldon was the first.

Kesem led me to move to Austin to work for the Livestrong Foundation. Kesem is how I met my wife. Kesem gave me the confidence to start Workweek and continue the path of building something from scratch.

But in reality, Aldon enabled all those things.

Throughout the years we had many amazing memories together. Having my wife and I vacation to his house in San Jose. Going to New Orleans for the Super Bowl and seeing his entire family make the trip. Meeting his son and watching him be a dad. The hilarious night we met Derek Jeter. Having the most intellectual conversations about life while playing Call of Duty.

I also saw him struggle. There's no doubt he was a complicated person. Truthfully, I don't know if he ever really figured out who he wanted to be. I know just because your'e 6'4, 250lbs, and get 5.5 sacks in a single NFL game doesn't necessarily mean you want to be a football player. No matter the reasons, he made many bad decisions in his life. Some of those mistakes made it hard for me to stay as close as we'd once been.

One day, not too long ago, I just decided to text him. It had been years since we really chatted. I just wanted to say thank you for all that he had done for me and that I was sorry I wasn't there for him more through his struggles. We FaceTimed after that, and it was like the old days all over again.

Aldon was more than the headlines, the mistakes. He was a generous, gentle soul, a kid at heart, someone who was endlessly curious about life... all in the body of a world class NFL player, bearing the weight of professional pressure and personal circumstances that most of us can't even imagine.

People are complex. People who make bad decisions can also do great things. A person can be hated by almost everyone and, yet, there are people in that person's life who still love them deeply.

I learned many of these lesson due to Aldon, and I'll carry them with me forever.

Rest in peace, Aldon. You won't be forgotten.

[takis @takisk]

@_iamlougotti bob sanders

[takis @takisk]

@yElff_ ochocinco would smoke you

[Bloody Elbow @BloodyElbow]

Bold outfit choice at the Misfits weigh-in. 👀 😳

[Hunter Biden @HunterBiden]

To everyone so eager to cancel someone for a tattoo they got at age 22, a drunk text, a selfie they took in the middle of a mental health crisis:

Show us your laptop.
Show us your iCloud.
Open your entire digital life to your worst enemy. No context. No filter. No explanation.

You won’t.

You won’t because you know what I know. Any one of us, frozen at our worst moment, photographed in our lowest hour, looks like a monster. Looks like a stranger. Looks like someone who deserves to be cast out.

That is not who we are.

My mom and baby sister were killed in a car accident when I was just a kid. Cancer took my brother Beau, my best friend and my rock. I battled alcoholism. I battled addiction. I chose the coward’s way out more times than I can count.

For years I believed the defining chapters of my life were written by tragedy, loss, and shame.

I no longer believe that.

Pain can shape us. Loss can humble us. Failures can leave scars that never fully fade. But none of them have the authority to define us.

And it sure as hell ain’t the critic that counts.

That authority belongs to us alone-the person in the arena.

Every setback presents a choice. Play the victim, or cut the bullshit and take ownership for who we become next.

Life does not determine our character. It reveals it.

Again and again we are asked the same question. When shit happens, what next?

We are not defined by what happened to us. We are not defined by the worst photo, the worst text, the worst tattoo, the worst night. We are defined by the person we choose to become. And by the courage to choose that person, every single day.

So before you reach for the gavel - show us your laptop.

You won’t.

The whole world saw mine. And I am still here. Still becoming. Still choosing. Still standing.

That is the only definition that matters.

[Blue Georgia @BlueGeorgia]

CNN montage of all the times Trump announced deals with Iran.

Anderson Cooper: Today marks 39 times that he has said something like that.

[🇺🇸Toska 🇦🇱 @ilirtoska]

@BigDadEnergyX I created a tracker in Claude to pull all the peptide research and provide the latest dosage protocols. This is what I am about to start:

[Overly Trev @OverlyTrev]

Wow, a phone teardown expert tries to school SpaceX aerospace engineers.

@ZacksJerryRig should stick to tearing down phones 📱

The flaw in your take: You nailed that 140°F radiates ~1,000x less per square inch than 3,272°F….

HOWEVER

You forgot area is adjustable.
Ever heard of the Stefan-Boltzmann law: Power = emissivity × constant × Area × Temp(K)^4

Using Grok we can fill in the math here.

To reject 150 kW at lower temp, you make the area bigger. That’s the entire point of a radiator panel.

Per the numbers: A 110 m² double-sided panel at 140°F with standard space coating radiates ~143 kW.

Satellites routinely deploy large radiators for exactly this.

No laws of physics are broken here.

Your “football field / ISS sized” claim is a wild exaggeration.

A 110 m² panel is manageable with Starship. The Soviet reactors were tiny hot systems for power generation; this is scaled waste heat rejection for compute.

Imagine telling SpaceX—the company with 10,000 satellites in space—how radiating heat in vacuum works.

SpaceX already uses Starlink V2 chassis bodies for conductive heat transfer.