Congratulations to @Tanes_Lima on this landmark study linking inhibition of ceramide synthesis with mitochondrial activation and clearance of protein aggregates in skeletal muscle https://t.co/fSjk8GkJdh
Check out our #review article in @NatureAging about the #pleiotropic effects of #mitochondria in #aging. We discuss how defects in mitochondrial stress pathways contribute to the decline in cellular & systemic #homeostasis in aging & age-related diseases. https://t.co/PpMqM0RaXK
Counteracting #RNAging promotes fast #muscles to slow #aging. Congrats to Martin for his publication in @ScienceTM! Read more about it here: https://t.co/vSlTSd1xi2
A potential new treatment for type 2 diabetes has multiple, positive effects on health and metabolism in mice, a Nature paper reports. The new drug might have potential for treating a variety of disorders in addition to type 2 diabetes. https://t.co/Lg7dJJnmfF
@NatureNeuro 𝗧𝗵𝗼𝗺𝗮𝘀 𝗠𝗶𝘀𝗴𝗲𝗹𝗱 lab has developed an approach to isolate cell-type-specific #mitochondria from mouse #CNS and demonstrate the proteomic diversity of cerebellar mitochondria. @TU_Muenchen#NatMetabPicks
https://t.co/sMgSgbBQsj
We are hiring!
If you enjoy science, metabolism and NAD+ biology, we are ofering a fully funded 2 year postdoc position! Cool labmates & chocolates included!
If interested, slap energetically on the link below and apply!
https://t.co/qXSyi01Hkq
Thanks in advance for RTing!!
Brown adipose tissue is a major consumer of branched chain amino acids (BCAAs) plus the identification of a mitochondrial BCAA transporter. #NatMetabPicks https://t.co/o9TXM6Pvy4
Our review on extracellular miRNAs is out in Cell Metabolism. What a birthday present!!
Extracellular miRNAs: From Biomarkers to Mediators of Physiology and Disease https://t.co/FbxLiENIET
Researchers used the “longevity signatures,” including up-regulation of oxidative phosphorylation and drug metabolism, to help identify drugs that might extend lifespan. (via @Cell_Metabolism) https://t.co/enJZRbSVNK
In case it helps anyone out there, I've uploaded our published methods for isolating nuclei from frozen tissues to @protocolsIO - https://t.co/thXhosKAuQ
This works for ATAC-seq, scATAC, ChIP, HiC, etc.
Essential role of the PGC‐1α/PPARβ axis in Ucp3 gene induction - Lima - 2019 - The Journal of Physiology - Wiley Online Library https://t.co/WRUj4bBLOq