Co-occurring mutations make better biomarkers to predict therapy response. Need better models to capture these associations with co-mutations. Foundation models can do this
@TreyIdeker#AACR26@AACR
Cancer is an evolutionary process. We've known this for decades, but we didn't know whether its complexity was tractable.
We now know we can measure and sometimes predict cancer evolution in patients from molecular ('omics) data, although with still suboptimal precision.
A way forward is combining evolutionary theory (maths and concepts from theoretical population genetics) with machine learning & AI, the latter filling the theory “gaps” when solutions from first principles are out of reach.
Building predictive models of cancer evolution means we may be able to control the disease, designing evolution-aware therapies that prevent or delay drug resistance.
Come to learn more about this at #AACR26 session: ED53 - Cancer Systems Biology, Ecology, and Evolution. https://t.co/ra7BjJ6DTK
Meet BioMedLM: a specialized language model trained on PubMed's vast biomedical literature. It's like having a medical researcher in your pocket, fine-tuned to understand complex scientific language and concepts.
In the UK, nearly 1 in 2 people will get cancer in their lifetime. It's World Cancer Day today – a global day to raise awareness and take action against cancer 🌍
Whatever your cancer experience, or however you’ve supported our work in the past, share this post and help us get the word out.
#WorldCancerDay #WCD2025
Free scientific illustrations for biologists! 😍
@NIH has released a library of 500+ free scientific illustrations to create figures, presentations, and illustrations!
all freely available in the public domain.
Retweet and spread the message!
https://t.co/p1bD1kxO7H
We are excited to kick off our series of 4 manuscripts from the RESOLUTE consortium by sharing the metabolic mapping of the Solute Carrier Superfamily (https://t.co/OAn581qvIN)!
Is your tissue larger than a @10xGenomics Visium capture area? If you need to stitch together the images but also the gene expression data, check our new preprint describing #visiumStitched
We also shared example postmortem human brain data (3 samples)
https://t.co/sYMH2V10JE
Alcohol causes cancer seven different types of cancer 🍺🍷
Whatever your drinking habits are, the less you drink, the lower your risk of cancer.
Here's some tips to get you started �Alcohol causes cancer seven different types of cancer 🍺🍷
Whatever your drinking habits are, the less you drink, the lower your risk of cancer.
Here's some tips to get you started �Alcohol causes cancer seven different types of cancer 🍺🍷
Whatever your drinking habits are, the less you drink, the lower your risk of cancer.
Here's some tips to get you started �Alcohol causes cancer seven different types of cancer 🍺🍷
Whatever your drinking habits are, the less you drink, the lower your risk of cancer.
Here's some tips to get you started �Alcohol causes cancer seven different types of cancer 🍺🍷
Whatever your drinking habits are, the less you drink, the lower your risk of cancer.
Here's some tips to get you started 👇
Want to annotate HLA/KIR genes and genotype them in a phased assembly? Try Immuannot, a new method from our group. It can identify novel alleles and reveal complex haplotype structures that short-read based methods may have troubles with. Available at https://t.co/ytvf4yH7uu
40% of unpaid carers say they have given up work to care for a loved one.
This #CarersRightsDay, we’re highlighting new legislation which gives carers the right to unpaid Carer’s Leave, helping them balance work and care.
Make sure you know your rights: https://t.co/dWnGesB1HI
In new work, @LambdaMoses et al. introduce the Voyager platform for spatial and non-spatial 'omics analysis:
🚴♀️ Builds on the geospatial statistics tradition
🚴♀️ Addresses discordance between Seurat & Scanpy
🚴♀️ Engineered in R (@Bioconductor) & Python
https://t.co/LR9hZdNRxK 1/🧵
Stop smoking services are vital resources to help people stop smoking successfully but due to lack of funding this support is not universally available. Join us in calling on the UK Government to change that ☟ https://t.co/9lEfThgJRP 3/3 https://t.co/9lEfThgJRP