Tom

PhD student in theoretical biological physics in the group of Chase Broedersz at the VU Amsterdam

[Tom @tb_physics]

Happy to share that our paper, which I have written together with Emily Brieger and @d_brueckner , Georg Ladurner, Joachim Rädler, and my supervisor @CBroedersz @PhysicsAstron_ has been published in PRX life! Check it out here: https://t.co/3BiTQOSICQ

[Tom @tb_physics]

Bonus: The interaction mechanisms that we learn for the cell types can be generalized to unconfined collective behavior, with our model capturing wound-healing experiments of epithelial and breast cancer cells previously studied in experiments.

[Tom @tb_physics]

Happy to share that our paper, which I have written together with Emily Brieger and @d_brueckner , Georg Ladurner, Joachim Rädler, and my supervisor @CBroedersz @PhysicsAstron_ has been published in PRX life! Check it out here: https://t.co/3BiTQOSICQ

[Tom @tb_physics]

Our results reveal a surprisingly simple, yet general quantitative theory of the dynamics of contact interactions, extending the general understanding of biophysical mechanisms of single-cell migration to interacting cells and revealing novel interaction modes in colliding cells.

[Tom @tb_physics]

We study cell-cell interactions of various migrating human cell types. Inspired by particle physics, we propose a set of eleven candidate contact-interaction mechanisms based on symmetry arguments. These mechanisms determine the dynamics of a minimal model for migrating cells.

[Tom @tb_physics]

What interaction mechanisms determine the behavior of motile colliding cells? And how do such interaction mechanisms vary across different cell types? 🤔In our new preprint, we address these questions!

[Chase Broedersz @CBroedersz]

🔥 new story🔥 We revisit a long-standing question regarding the role of entropy in bacterial chromosome segregation. We find that purely entropic forces actually inhibit segregation until late stages of replication, but loop extruded change everything… https://t.co/vPLCx6GtoE

[Tom @tb_physics]

The inviting groups are the ones from @CBroedersz, Tom Shimizu and Pieter Rein ten Wolde @_amolf. Sign up here: https://t.co/W9rg1gpR3m

[Tom @tb_physics]

Listen up! If you are a researcher in the Netherlands working at the intersection between experimental and theoretical physics of life, we would like to invite you to a day of talks, discussions and networking to Amsterdam! See the attached flyer for more info!

[Physics and Astronomy Amsterdam🔭 @PhysicsAstron_]

Our latest colloquium🎥 👩🏻‍🔬 🥳

[Physics and Astronomy Amsterdam🔭 @PhysicsAstron_]

📢Exciting discovery from our department Assoc. Professor @CBroedersz and his team have just published a ground breaking paper on collective cell migration in curved environments @NatureComms

Check it out here: https://t.co/gDPNpchcjW

#cellmigration #3Dcurvedtissues #Science

[Tom @tb_physics]

This was only possible because of great team effort! Thanks to all authors and everyone involved! And especially thanks to my co-first author @d_brueckner and my supervisor @CBroedersz

[Tom @tb_physics]

I am delighted to share that our paper on curvature-induced velocity waves in rotating cell spheroids that I wrote together with @d_brueckner and our co-authors Yu Long Han, @RicardAlert, Ming Guo, and @CBroedersz has been published! 🥳

Check it out here: https://t.co/le72cdCAAJ

[Tom @tb_physics]

The robustness and genericness of our active particle model is a reason to hope to see these waves also in other curved cell tissues or maybe even in more general curved active matter systems! Also, it would be so cool to find out if biological processes even rely on these waves!