Dat Nguyen

Junior scientist, hobbyist, bookaholic. Worked in education, microbiology lab/winery, now in computer-aided science.

[Dat Nguyen @thanhdat_bio]

Many comments about clusters detection. A good point to remember.

[Albert Rapp @rappa753]

Correlation matrices are super hard to read. Instead, I like to use lollipop charts.

Left: Correlation
Right: Lollipops

[Elisabeth Bik @MicrobiomDigest]

One of the world’s most cited scientists, Rafael Luque, suspended without pay for 13 years
The prolific chemist, who has published a study every 37 hours this year, has been sanctioned by the University of Córdoba

⁦@manuelansede⁩ reports https://t.co/DvtgsTV6sP

[Trung Phan @TrungTPhan]

Salvador Dalí painted some of the trippiest art ever.

His surrealist work expressed the unconscious mind (eg. the iconic 1931 “Persistence of Memory”).

To tap this creative space, Dalí frequently used a micro-nap technique called “slumber with a key”

In his words:

1️⃣ “You must seat yourself in a bony armchair, preferably of Spanish style, with your head tilted back and resting on the stretched leather back.”

2️⃣ “Your two hands must hang beyond the arms of the chair, to which your own must be soldered in a supineness of complete relaxation.”

3️⃣ “In this posture, you must hold a heavy key which you will keep suspended, delicately pressed between the extremities of the thumb and forefinger of your left hand.”

4️⃣ “Under the key, you will previously have placed a plate upside down on the floor.”

5️⃣ “The moment the key drops from your fingers, you may be sure that the noise of its fall on the upside down plate will awaken you.”

Dali wanted to achieve a state of “sleeping without sleeping”, which he said was the”most appropriate to the art of painting.”

In scientific terms, Dalí was trying to get to hypnagogia (a transition state between wakefulness and sleep, where individuals can experience unusual sensory perceptions or hallucinations).

While in hypnagogia, the judgy conscious mind takes a back seat. And the semi-conscious mind is able to make new insights and connections that might otherwise *not* have been made.

Back to the “Persistence of Memory” painting: Dali said the inspiration for the melting clocks was the image of melting camembert cheese. But late in life, Dalí also credited Albert Einstein’s theories on space and time as another creative input.

Perhaps unsurprisingly, Einstein was also a practitioner of micro-naps while sitting in a chair. But instead of “slumber with a key”, Einstein did “slumber with a spoon.”

[Machine Learning in Chemistry @ML_Chem]

Generating Protein Folding Trajectories Using Contact-Map-Driven Directed Walks #machinelearning #compchem https://t.co/E1ENh8ohSh

[Dat Nguyen @thanhdat_bio]

@AlexGoldberg_ @JimProudfoot Care to change you bio from "loudmouth" to "silence"?

The last 2 matches you were eerily silent. Your latest posts in Patreon were about podcast guests, your IG post were only about (future) players.

You don't care much about the current situation, do you?

[Trung Phan @TrungTPhan]

Went down a rabbit hole for cross-industry innovations (when one industry borrows from another).

Here are 8 gems.

1. James Dyson made a bagless vacuum after seeing how sawmills used cyclone force to eject sawdust.

[Kresten Lindorff-Larsen @LindorffLarsen]

I am beyond thrilled to announce that we (me 🇩🇰, Eike Schulz 🇩🇪 & Mikael Akke 🇸🇪) have been awarded an ERC Synergy Grant 🇪🇺 🎉

In #DynaPLIX we will combine NMR 🧲, time-resolved crystallography ⚡️ & simulations 🖥️ to study how ligands bind to proteins

https://t.co/YUVPRP37ne

[Roshan Patel @roshanpateI]

I was rejected by Apple.
I was rejected by Amazon.
I was rejected by Facebook.

I was 28 years old and broke.

I decided to start my own startup.

Now I’m 30 years old and broke.

[Seagate Gaming @seagategaming]

🚨GIVEAWAY ALERT🚨

10 Game Drives for PlayStation are up for grabs and you can be the lucky one. Click to join today: https://t.co/HE0ZR7Dmxt

Entry closes on 19 Jan 2023.

*Open only to legal residents in Australia, New Zealand, India, Indonesia, Vietnam & Thailand. T&Cs apply.

[Tiago Peixoto @tiagopeixoto]

Taking a closer look at this paper, I really dislike it.

It's clear that newer papers *must* have a lower “disruption” score than older ones under a null model — they even confirm this in the supplemental material with a randomization test.

https://t.co/tcWhqBssQN

[Lex Fridman @lexfridman]

I'm reading a book a week in 2023. Classics, sci-fi, nonfiction, or anything people highly recommend. I'll keep adjusting the list. Start on Monday, done by Sunday. Might make lowkey videos of takeaways. If you want to read along, the current list is here: https://t.co/hYCs1pvLiZ

[Prof. Nikolai Slavov @slavov_n]

Google finds 13,400,000 instances of this nonsense:

"gene expression and protein expression"

The hits are from academic papers.
> They confuse "gene expression" with RNA abundance and "protein expression" with protein abundance.

Sloppy Language <---> Sloppy Thinking

[Ming "Tommy" Tang @tangming2005]

Open Source Society University

🔬 Path to a free self-taught education in Bioinformatics!

https://t.co/ahSwaYN4mm #Bioinformatics

[Dat Nguyen @thanhdat_bio]

Thanks @pmcomposer for spending 4,921 minutes with me in 2022. I couldn’t stop listening to Frostpunk Theme. #SpotifyWrapped https://t.co/Sok99rm0qF

[Arvind Narayanan @random_walker]

I know grad school is competitive, but being offered a bribe by an applicant was unexpected.

I wonder how often this succeeds.

[Bioinformatics Program at University of Lethbridge @Bioinfo_ULeth]

Interested in studying #bioinformatics? 🖥️🧬

The Graduate Certificate in Bioinformatics a 6-month program with evening classes, hands-on learning and options for remote attendance.

Submit your application until December 1st! #uleth #yql

https://t.co/OUMBu584HV

[Alex Xu @alexxubyte]

/1 I’ve been writing the system design newsletter for 6 months. Here are the 5 most popular ones: 👇

Link: https://t.co/0RYwcKv26q

[Abdel Abdellaoui @dr_appie]

Which paper(s) have taught you a lot about genetics? 📃🧬

[Dat Nguyen @thanhdat_bio]

#QuanQuanGCP Such a tiring experience.
My profile: https://t.co/SbdNzWi2rl

[Jay Keasling @jaykeasling]

Our latest research has just been published today in the journal Nature. We engineered yeast to produce the cancer therapeutic vinblastine. You can find the work here: https://t.co/kJdVcPDEM1. It is the longest biosynthetic pathway ever refactored into yeast.