Here’s my guide to navigate the #ACC25 trials, coming this weekend and featured in many journals with a (very) high impact factor.
1. WARRIOR = Intensive medical therapy in women with ANOCA/INOCA
2. STRIDE = Semaglutide in type 2 diabetes and peripheral artery disease
3. API-CAT = Reduced-dose versus full-dose apixaban in cancer with VTE
4. FARES-II = Four-factor prothrombin complex in cardiac surgery
5. REVERSE-IT = Bentracimab in uncontrolled bleeding or requiring urgent surgery or invasive procedures
6. RIVAWAR = Rivaroxaban versus warfarin in left ventricular thrombus after MI
7. SOUL = Oral semaglutide in type 2 diabetes with ASCVD and/or CKD
8. ADVANCE-HTN = Lorundrostat in uncontrolled hypertension
9. DapaTAVI = Dapagliflozin in transcatheter heart valve treatment
10. MIGHTy-Heart = Two strategies for improving transition to home after heart failure hospitalization
11. FRESH-UP = Liberal versus restrictive fluid intake in chronic heart failure in outpatient setting
12. FAIR-HF2 = Intravenous iron in heart failure with iron deficiency
13. PROTECT-TAVI = Embolic protection in TAVI
14. ALIGN-AR = Dedicated transcatheter aortic valve in aortic regurgitation
15. Evolut Low Risk = TAVI in low-risk
16. FLAVOUR II = Angiography-derived FFR versus IVUS in PCI
17. TRILUMINATE = Tricuspid transcatheter edge-to-edge repair in tricuspid regurgitation
18. FAME 3 = FFR-guided PCI versus CABG in multivessel disease
19. RACER = Out-of-hospital cardiac arrest during long-distance running events
20. Altshock-2 = Intra-aortic balloon pump in heart failure complicated by cardiogenic shock
21. ECLIPSE = Intravascular imaging to guide PCI of severely calcified lesions in PCI
22. HOST-BR = DAPT duration based on bleeding risk
Members from #ACCWIC and #ACCCVManage Member Sections developed a toolkit focusing on how to start a heart center for women & how to manage the care of women w/ or at risk for #CVD.
Learn more and access the toolkit here: https://t.co/251d6kcH7m
Dr. Ileana Pina shares tips for success to enroll more women in clinical trials:
1) Women in clinical trial leadership
2) Convenience of research measures and enrollment— enroll in clinic and in presence of patient’s families
3) budget for transportation/partner with rideshare
#ACC24 LBT: DanGer Shock
- 355 Danish/German/UK (79% male) patients post-AMI in cardiogenic shock were randomized to ImpellaCP+standard care vs. standard care only
- Significant ⬇️ 1° endpt of death from any cause at 180d
- But ⬆️ risk of bldg, RRT, sepsis
@CardiacTrials
@HarborUCLA Cardiology Representation at #ACC24!!
#ACCFIT with our attending Dr. Chung
Much gratitude to our PD @BudoffMd for enabling us all to attend a 🫀 conference every year! 🙏
#ACC24 Late Breaking Trial: REDUCE-AMI
- Approx 5000 patients who were post MI and had LVEF >= 50% were randomized to beta blocker vs. no blocker
- Median follow-up of 3.5 years
- No difference in primary endpoint of all-cause death or MI, or secondary endpoints!
@CardiacTrials
🔥Highlights from the Late breaking SMART trial studying Self-Expanding vs. Balloon-Expandable TAVR in patients with small aortic annuli - that enrolled 75% women! 🔥
#ACC24@CardiacTrials
#AHA22 LBCTs one liners:
1. TRANSFORM-HF: Torsemide was not superior to furosemide in improving survival among patients treated for decompensated HF.
2. DCP: No differences in cardiovascular outcomes between chlorthalidone and HCTZ among elderly veterans with HTN.
Thankful for the great discussions ranging from being a woman cardiologist to women’s CV health with @DrMarthaGulati, especially in regards to more awareness required for CVD in the South Asian community!
UCSF Cardiac Hospitalists at #ACC22! 🫀
I’ve had an incredible time so far learning about late breaking clinical trials, new ACC guidelines, catching up w old friends, making new ones, and much more.
2022 ACC/AHA/HFSA HF guidelines are out. I would like to thank the writing group members and the the staff for their tireless efforts. We are excited and encourage all clinicians to check it it out . New Recommendations & helpful figures https://t.co/OvVwkSBWFI