theNNT.com

Independent reviews of highest quality evidence by practicing clinicians & EBM experts evaluating therapy based on patient-important benefits.

[Ken Milne MD @TheSGEM]

Journal retracts study linking hepatitis vaccine to autism that was included in CDC review https://t.co/douYyjVmqL

[theNNT.com @thenntgroup]

What is the diagnostic accuracy of lung ultrasound findings for pneumonia in adults?

Learn more from the Brass Tacks review article via @AcademicEmerMed - https://t.co/ltr0KWd8E5

Read more from the @thenntgroup - https://t.co/J3MYjH1iKZ

#NNThursday #FOAMed

[theNNT.com @thenntgroup]

@critcareguys, @precordialthump, @PulmCrit, @emcrit, @CriticalCareNow, @Crit_Care, @JohnGreenwoodMD, @CHsu1012, @ResusReview, @intensiveblog

[theNNT.com @thenntgroup]

What is the diagnostic accuracy of lung ultrasound findings for pneumonia in adults?

Learn more from the Brass Tacks review article via @AcademicEmerMed - https://t.co/ltr0KWd8E5

Read more from the @thenntgroup - https://t.co/J3MYjH1iKZ

#NNThursday #FOAMed

[Shahriar Zehtabchi @SZehtabchi]

Great piece published in Academic Emergency Medicine on how institutions are often pressured to sacrifice high-quality patient care in order to meet performance metrics. @AcademicEmerMed
https://t.co/TS0E9NmTeR

[NBC News @NBCNews]

No child deaths have been definitively linked to Covid vaccines, according to a report from the FDA that was quietly made public. https://t.co/N99uOgFTQ9

[emresidents @emresidents]

“Dead Tired” from Nathaniel Ladaga, DO and Elizabeth Nisper, MD, highlights how sleep loss impacts performance, safety, and burnout in the ED. Plus, find out how programs should prioritize smart scheduling to support residents' sleep: https://t.co/szOxyqURg7

#Wellness #Sleep

[Eric Topol @EricTopol]

Supplementation with Vitamin D or calcium, or both does not help prevent fractures or falls. From a new systematic review of 69 randomized trials and >150,000 participants

[theNNT.com @thenntgroup]

@critcareguys, @precordialthump, @PulmCrit, @emcrit, @CriticalCareNow, @Crit_Care, @JohnGreenwoodMD, @CHsu1012, @ResusReview, @intensiveblog

[theNNT.com @thenntgroup]

What is the benefit of alpha-lipoic acid for diabetic peripheral neuropathy?

Learn more from the Brass Tacks review article via @aafp - https://t.co/g4tup3DzZW

Read more from the @thenntgroup - https://t.co/xzHGv9nw2h

#NNThursday #FOAMed

[theNNT.com @thenntgroup]

@emlitofnote, @spoonfedEM, @EMNerd_, @SketchyEBM, @TheSGEM, @Runde_MC, @grahamwalker, @alimkakeng, @Hinson_EM, @ndubosh, @SMTEvidence, @klinelab, @WeAreCanadiEM, @EBMgoneWILD, @SAEMEBM, @DwiebeD, @TheSGEM, @JeremySussman, @ehlJAMA, @AudreyBlewer, @patcroskerry

[theNNT.com @thenntgroup]

What is the benefit of testosterone replacement in men with sexual dysfunction in the absence of hypogonadism?

Learn more from the Brass Tacks review article via @aafp - https://t.co/wmtB2qFGMx

Read more from the @thenntgroup - https://t.co/4BaFGsRjVI

#NNThursday #FOAMed

[Dr. Filippo Cademartiri @FCademartiri]

This article should be mandatory reading for every medical student, PhD candidate, researcher—and honestly, for anyone who mistakes expertise for certainty.

“The importance of stupidity in scientific research” sounds provocative, almost offensive. But Martin Schwartz is not glorifying incompetence. He is describing the real operating system of discovery.

Science is not built on knowing.
Science is built on tolerating not knowing.
That distinction matters.

Most of education rewards correctness.
School teaches us to answer.
Exams reward speed, certainty, and precision.
You feel intelligent when you get things right.

Research is the opposite.
Real research begins exactly where competence ends—at the frontier where nobody knows the answer, including the people you thought must know.
That moment is psychologically brutal.
You ask the expert.
The expert shrugs.
You assume you’re missing something.
Then you realize: no—this is the work.

You are not failing.
You are standing at the actual boundary of knowledge.

That feeling—“I must be stupid”—is often not a sign of inadequacy.
It is often the first sign that you are finally asking an important question.

Medicine struggles with this.

We train doctors to avoid uncertainty, to fear being wrong, to perform confidence.
But the best clinicians and the best scientists know how to sit inside ambiguity without collapsing into fake certainty.
This is why AI in medicine also deserves caution.
Systems trained only to reproduce established answers may become extraordinarily good at passing exams while being terrible at discovering what matters next.
Guideline intelligence is not the same as scientific intelligence.
Discovery requires productive stupidity:
the willingness to stay with the uncomfortable,
to look ignorant,
to ask naïve questions,
to be wrong repeatedly without protecting your ego.

Most people want the authority of expertise.
Very few want the humiliation required to earn it.
But progress lives there.

Not in certainty.
Not in performance.
Not in sounding smart.
In the quiet discipline of saying:
“I don’t know… yet.”

And continuing anyway.

[Dr. Catharine Young @DrCatharineY]

A new warning by @TheLancet for the American people: the CDC is “on the brink” of collapse.

“The CDC was once the gold standard for public health leadership. Today, it is struggling to maintain scientific excellence, trustworthiness, and relevance, a result of the actions of the Trump admin and HHS that have undermined the agency.”

[theNNT.com @thenntgroup]

@painfreeED, @drrobbietee

[theNNT.com @thenntgroup]

What is the benefit of sustained-release naltrexone for opioid dependence?

Learn more from the Brass Tacks review article via @aafp - https://t.co/bondGtv6Rw

Read more from the @thenntgroup - https://t.co/yiDorTlsBl

#NNThursday #FOAMed

[The Washington Post @washingtonpost]

A report showing the efficacy of the covid-19 vaccine that was previously delayed by the head of the CDC has been blocked from being published in the agency’s flagship scientific journal, according to people familiar with the decision. https://t.co/ZUJp9pmU74

[JAMA @JAMA_current]

💬 Viewpoint: Mandatory annual training modules consume millions of physician‑hours each year, yet their largely passive formats may offer limited educational value while contributing to administrative burden and clinician burnout.

https://t.co/mJ4oi68waA

[Laura Vater, MD, MPH @doclauravater]

Four million physician hours are spent on mandatory modules each year. They represent not just clinical time lost but “evenings reclaimed and cognitive load reduced.”

Redundant training and low-value modules should be a thing of the past.

https://t.co/896bWbZoVQ

[Ken Milne MD @TheSGEM]

5 Logical fallacies in the era of RFK Jr. https://t.co/FBwgtcbVU4