Treatment resistance remains a major challenge in HR+/HER2- breast cancer, even with progress from endocrine therapies and CDK4/6 inhibitors.
In a new Q&A with @curetoday, @KaziaTx CEO Dr. John Friend discusses expanding our paxalisib trial into this population, building on preclinical findings suggesting the drug may resensitize resistant tumors to CDK4/6 inhibition.
He also addresses how paxalisib's brain-penetrant design may relate to its broader biological effects, and how biomarker research could help identify which patients are most likely to benefit.
https://t.co/Ulj8LyGTw3
#BreastCancer #Oncology #ClinicalTrials #Paxalisib
New in @curetoday: @KaziaTx is expanding our #paxalisib trial to HR+/HER2- metastatic breast cancer patients who've progressed on prior treatment.
Can we help resistant tumors respond again? CEO Dr. John Friend explains - it's about reversing the biology of resistance.
https://t.co/NkXtrSEvvR
#BreastCancer #Oncology #ClinicalTrials #CancerResearch
$KZIA @KaziaTx ICYMI Should be 3 sell side initiations
on Kazia - imminently- The 3 banks who placed deal 3 weeks ago at $15.50 Leerink, Guggenheim, Needham
$KZIA @KaziaTx Research note just in from BTIG:
Kazia Therapeutics Limited (KZIA, Buy 40.00): Evaluation in Rare Epilepsies To Further Validate Pax's Broad CNS Utility $IBB $XBI
$KZIA Nice win this morning 🔥
Partner Sovargen just dosed the first patient with paxalisib in rare, treatment-resistant epilepsies. Kazia gets $2M cash, with up to $17M more in milestones plus royalties on the table
Zero approved drugs for FCD type 2 today, so real unmet need. And Kazia doesn't spend a dime, Sovargen funds it
Same molecule, more shots on goal, all while the TNBC story keeps building
Long $KZIA, not advice
https://t.co/2MySsaH5fd