Best Kinase Inhibitor Set. Ever.

188 inhibitors across 210 #kinases. A product of #openscience, inspiring the discovery of pioneer medicines

[Best Kinase Inhibitor Set. Ever. @therealKCGS]

A collaboration with UNC virologists using @therealKCGS led to this —> https://t.co/tbR6x67ejy

[Best Kinase Inhibitor Set. Ever. @therealKCGS]

Host kinase CSNK2 is a target for inhibition of pathogenic β-coronaviruses including SARS-CoV-2 https://t.co/JK4lwmKIar

[Best Kinase Inhibitor Set. Ever. @therealKCGS]

An ATP-competitive kinase inhibitor with exquisite selectivity. How? Read on....⁦@thesgconline⁩ ⁦@DruggableGenome⁩ https://t.co/vWLKd55Z71

[aled edwards @aledmedwards]

Cheryl announcing #Target2035 webinar series at today’s kick-off meeting. Looks exciting! ⁦@CherylArrowsmi1⁩

[Best Kinase Inhibitor Set. Ever. @therealKCGS]

Meet the talented Alison Axtman from our team @UNC @thesgconline https://t.co/WxZeLYPgd3

[Best Kinase Inhibitor Set. Ever. @therealKCGS]

With our friends at Promega we built the first map of CDK drug selectivity in live cells across the whole family: CDK1-20 #openscience #chemogenomics
https://t.co/Y3bOSKkM65

[Best Kinase Inhibitor Set. Ever. @therealKCGS]

@thesgconline @UNCPharmacy @UNC_SOM launch a big open science initiative to develop drugs for viruses with pandemic potential #beREADDI #hosttargets https://t.co/ixW5XbH1aQ

[aled edwards @aledmedwards]

A group of us around the world are creating an #openscience non-profit to invent drugs explicitly to put on the shelf for the next pandemic. We started the project last summer, but should have started a decade ago…damn. Announcement this week or next. @thesgconline

[The University of North Carolina at Chapel Hill @UNC]

Researchers at @UNCpublichealth are testing an antiviral drug that shows promise as a possible treatment for COVID-19. #UNC’s Ralph Baric heads the lab developing the broad-spectrum antiviral that could potentially provide relief to the global pandemic https://t.co/W1lODdw08r

[Best Kinase Inhibitor Set. Ever. @therealKCGS]

@thesgconline scientists Alison Axtman and Carrow Wells on the cover. On the inside their paper describing SGC-AAK1-1 a chemical probe for AAK1/BMP2K #WomenInScience

[ACS Med Chem Lett @ACSMedChemLett]

Check out the joint Special Issue "Women in Medicinal Chemistry" with @JMedChem out today that showcases the excellent work performed by women in the field: https://t.co/IBlTGX1hqt

[Best Kinase Inhibitor Set. Ever. @therealKCGS]

Round table discussion at PharmSci 2020 about the social and economic impact of #openscience @UNCPharmacy

[Best Kinase Inhibitor Set. Ever. @therealKCGS]

@aledmedwards kicking off PharmSci 2020 meeting today showcasing #openscience and #drugdiscovery.

[Ximbio @Ximbio]

Discover a new #Kinase Chemogenomic Set from @therealKCGS https://t.co/uRzXRkpWDP #datasheet #lifesciences #reagents #inhibitors

[The Mark Foundation for Cancer Research @TheMarkFdn]

Proud to announce today an expansion of our partnership with @ChordomaFDN to accelerate drug discovery in an open-source way! CC: @dhdrewry @UNCPharmacy @ICR_London @PaulWorkmanICR @thesgconline https://t.co/JNWFXMjJQz

[Chordoma Foundation @ChordomaFDN]

Together with @TheMarkFdn, we are proud to announce a two-year, $1.4M grant to researchers @PaulWorkmanICR @dhdrewry @Ogileadi focused on creating the first drugs capable of targeting #brachyury, the Achilles’ heel of #chordoma https://t.co/0YCoGDBYxC

[Best Kinase Inhibitor Set. Ever. @therealKCGS]

Want to learn how #openscience will lead to affordable medicines? Come to the #pharmsci2020 symposium @UNCPharmacy in Chapel Hill on Tuesday #SGC-UNC #drugdiscovery https://t.co/FLqXAFPxpN

[Dr. Arij Al Chawaf @ArijAlChawaf]

ICYMI: Check out the Kinase Chemogenomics Set (KCGS): 187 inhibitors for 215 kinases. A collaborative resource meticulously developed & curated by the SGC-UNC team. https://t.co/FRrDtFZEVn More details here on @biorxivpreprint https://t.co/GOtJmRyzCO #openscience

[Best Kinase Inhibitor Set. Ever. @therealKCGS]

[Part 2] ...This collaboration has resulted in multiple publications and grant funding as a specific result of these interactions. - Lee Graves, PhD, Professor in Department of Pharmacology @UNC_SOM Read more about Dr. Graves and his KCGS Collaboration --> https://t.co/QdBakILvGV

[Best Kinase Inhibitor Set. Ever. @therealKCGS]

[Part 1] My lab and I have greatly benefited from using KCGS in investigating cellular mechanisms of drug resistance in cancer by the application of chemogenomic libraries to discover novel kinase targets for pancreatic cancer treatment...

[Best Kinase Inhibitor Set. Ever. @therealKCGS]

We are proud to work with @boehringerus and their #OpnMe platform to encourage open collaboration between scientists! Check out the work they do at https://t.co/MvT30zSsVH and become a part of the KCGS open science community at https://t.co/QdBakItUil!

[Boehringer Ingelheim @boehringerus]

We are proud to contribute to @therealKCGS’s #openinnovation initiative by donating 17 kinase inhibitors to their Kinase Chemogenomics Set. Learn more on #opnMe: https://t.co/yXz9thmC6n