Thilo von Groote

Medical doctor & clinical researcher. Acute kidney injury (AKI)🔬, vasoplegic shock🫀, data science 🖥, critical care 🚑. coordinating the BigpAK-2 Trial

[Intensive Care Medicine @yourICM]

Precision management of #AKI in #ICU
🫘 sub‑phenotypes, endotypes, treatable traits
🫘 acute kidney injury? Heterogeneous syndrome (not disease!)
🫘 identification of sub‑phenotypes
🫘 proposed specific management approaches
🫘 practical recommendations
🖇️ https://t.co/oRYCg4jF0K

[Intensive Care Medicine @yourICM]

🫘 EPIS #AKI, epidemiology of major surgery associated acute kidney injury
➡️ > 10K pts, 1/5 develop PO-AKI: significant burden for health care worldwide!
⬆️ increasing severity of PO-AKI associated with progressive increase in adverse outcomes
#FOAMcc
🖇️ https://t.co/Ps7N7zoMKP

[tagesthemen @tagesthemen]

Die Würde des Menschen – ist längst nicht mehr unantastbar für die AfD.
Ist die Partei also verfassungsfeindlich? Was denn sonst, frage ich.
Die Meinung von @gaborhalasz1 zum Bundesparteitag der #AfD. #AfDBPT23

[Giovanni Landoni, MD @giovannilandoni]

Angiotensin II suppresses renin release!

with Coulson TG @BellomoRinaldo we documented it in @BJAJournals in #cardiacsurgery Higher plasma renin concentration before surgery was associated with greater vasopressor requirement for #norepinephrine, but not #angiotensin II

[Thilo von Groote @thilo_vg]

Great paper by @CelineMonard , Antoine Schneider and Co.! 👏🏼 couldn‘t agree more…

[BMC @BioMedCentral]

A study in @Crit_Care confirms that the current consensus threshold of 0.5 ml/kg/h over six hours to define oliguria may be too conservative. A cut-off of 0.2 ml/kg/h over three or six hours should be considered in definitions of oliguria.
https://t.co/NxErvxbD68

[Ingwar Perowanowitsch @Perowinger94]

Gestern wurden die Sitzbänke der Friedrichstraße entfernt. Wo tausende Menschen sich bisher vom Verkehrswahnsinn erholten, verpesten ab morgen wieder Autos diesen Ort. Berlins Straßennetz ist 5300km lang, aber 500m davon autofrei war für die CDU "grüne Ideologie". So unfassbar.

[Thilo von Groote @thilo_vg]

@paul_rottger @oiioxford @computermacgyve @MaartenSap Congrats Paul! 👏🏼

[Javier Ripolles-Melchor @germ_red]

🩺 Postoperative complications still occur despite technological advancements & care pathways. Intraoperative hemodynamic therapy can optimize oxygen delivery & improve outcomes. Let's explore our new trial: the Predict-H multicenter trial on hemodynamic optimization! - Thread

[Ashish K. Khanna, MD,MS,FCCP,FCCM,FASA @KhannaAshishCCM]

Another important contribution to the “early multi-modal vasopressors” concept - Ang II at NED <0.25mcg/kg/min nearly halved the risk of death! Great collaboration @pwierusz @BellomoRinaldo @JonathanChowMD @Crit_Care @SCCM @SOCCA_CritCare

https://t.co/N3aloRY70M

[Johannes Wagner, MdB @yooHannes]

Die #FDP hat großen Klärungsbedarf!

#Klimaleugner #EIKE #Doepfner #Wissenschaft

https://t.co/8oE9lsHzwC

[Intensive Care Medicine @yourICM]

Acute kidney injury common in #ICU, influencing outcomes: not only focus on prevention, optimize treatment! In this review:
🫘 prevention
🫘 conservative management
🫘 optimal timing of initiation of RR
🫘 longer-term post #AKI follow-up
@ForniLuiG
🖇️ https://t.co/SPz70YfJIK

[Thilo von Groote @thilo_vg]

@rakanesthesia @germ_red Thanks for all your commitment @rakanesthesia ! ✊🏼 keep up the great work!

[Raquel García @rakanesthesia]

Thanks to @thilo_vg , @germ_red and all the team #AKI
Biomarker-guided intervention to prevent acute kidney injury after major surgery (BigpAK-2 trial): study protocol f… https://t.co/xedEtE1fuC

[Thilo von Groote @thilo_vg]

New paper in @CritCareMed: what is better than furosemide stress test (FST) to predict worsening of #AKI in an ICU-patient? Combine FST with a kidney biomarker! Best performance for CCL14 with FST. Paper available #openaccess at https://t.co/3UjaWw0AaD

[M Velia Antonini @FOAMecmo]

🫀 Airway management during #ACLS in refractory #OHCA: in pts under prolonged CPR, endotracheal intubation associated w ⬆️ oxygenation/ventilation at evaluation for #ECMO vs supraglottic airways, with ⬆️ #ECPR candidacy/⬆️ neuro-outcome. @ResusJournal
🖇️ https://t.co/Qy4c3gxomL

[Thilo von Groote @thilo_vg]

@germ_red @NephroGuy @caldecoaal @mjcolomina Interesting study!

[Silvia De Rosa @SilviaDeRosa11]

Finally…We have a new Consensus Statement online: Sepsis-associated acute kidney injury: consensus report of the 28th Acute Disease Quality Initiative workgroup#sepsis #extracorporealbloodpirification #endotypes #phenotypes #biomarkers #fluidmanagement

https://t.co/col9ZMWYoY

[Annette Dittert  @annettedittert]

Brilliant in depth (long) read on why so many Germans still struggling with supporting Ukraine militarily. ⁦@hoyer_kat⁩ https://t.co/rih0f6pIEs

[ESICM @ESICM]

A cluster-randomised trial among 6 🇨🇦 paramedic services evaluated double sequential external & vector-change #defibrillation vs standard defibrillation in patients with refractory ventricular fibrillation in #OHCA.

#VisualAbstract by #ESICMNEXT @emilio_r_ruiz

#IntensiveCare