Dr. Stephen Harrison presents up to the minute data in his truly inspiring presentation at the Desert Liver Conference.
Some key-always:
In the “diabetic population, almost every single diabetic will have some degree of fatty liver. But maybe the more interesting fact is 37% of them, when you stick a needle in their liver, have steatohepatitis, and even more striking, 17% of those will have advanced liver disease. So 17 out of 100 diabetics, just broad strokes, will have advanced liver disease, and most do not know that they have this.��
“The more you move, the better the health benefit. You don't have to be in zone 2 all the time, or zone 3, or zone 4. You don't have to be sweating to the oldies and slinging sweat everywhere, okay? You just have to move, and this data suggests in almost a quarter of a million patients in 17 different studies, that for every 1,000 steps that you take, you reduce alcohol's mortality by 15%. Even a 500 step increment drops CV mortality by 7%.”
“What about alcohol, smoking, fructose, and coffee? Well, the answer there is less is more for alcohol. In fact, I advocate no alcohol in our patients that have fibrosis. I think that's counterproductive, counterintuitive. Same thing with smoking. Fructose, I advocate for not drinking or ingesting fructose-containing beverages, that just revs up de novo glycogenesis in the liver and adds to fat.”
“Now, when we think about lifestyle modification, we talked about cutting calories, cutting carbs, and I'm a big advocate for that. Reducing caloric intake and weight loss of at least 10% or more has been shown to improve not only the steatohepatitis, the inflammation, the liver cell injury, the fat, but also the fibrosis. And exercise, we cannot say that enough. Exercise is critically important, but here's a little caveat about exercise. You cannot out-exercise the fork.”
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So much has been written about me in the past. I thought it was time people heard from me. The highs were high, the lows were low. But I have lived to tell the tale, even though at times it looked like I wouldn’t. And it’s all in here. I apologize it’s not a pop up book.
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That must change.
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Image 3 of 4: Pirates of the Caribbrain: The Curse of the Plaque Pearl
A protein called complement receptor 1 (CR1) is found on microglia and astrocytes (red) and amyloid-beta plaques (green/yellow) in the Alzheimer's disease brain.
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Great days at #SLDsummit in Prague - now we thank the 🤩⭐️faculty for their contributions 🙏 off to faculty dinner and the traditional female only photo 👍