Thomas Renné

Professor of Clinical Chemistry, MD PhD, fascinated in the crosstalk of coagulation and inflammation, factor XII, polyphosphate, vascular biology

[Thomas Renné @thomas_renne]

Factor XII drives thrombosis but is dispensable for hemostasis, making it an anticoagulant drug target. We show that factor XII–triggered coagulation traps pathogens and limits bacterial dissemination, highlighting a role of prothrombotic mechanisms in innate immunity.

[Thomas Renné @thomas_renne]

https://t.co/y4GNmplQYz

[Thomas Renné @thomas_renne]

Ausschreibung: W2 Professur für Translationale Präzisionsdiagnostik am UKE

[Thomas Renné @thomas_renne]

Opportunity for fans of thrombosis and homeostasis. Join our team! https://t.co/IW2dfwnVTi

[1. FSV Mainz 05 @1FSVMainz05]

🕺🏻🕺🏻🕺🏻

[Thomas Renné @thomas_renne]

@VascSensing_Lab @UKEHamburg Congratulation!

[ISTH @isth]

We regret to share that Claire McLintock (@doctormclintock), passed away on December 23, 2022. Claire served the @ISTH in many positions, including as ISTH President from 2018-2020. She was a brilliant, bright light and will be greatly missed. Read more: https://t.co/WOXZSrmVCd

[Thomas Renné @thomas_renne]

Intrinsic coagulation pathway-mediated thrombin generation in mouse whole blood https://t.co/LOFP1rdrjW

[Thomas Renné @thomas_renne]

Dec 5, 1994. Russia guaranteers the sovereignty of Ukraine (German news)

[Thomas Renné @thomas_renne]

https://t.co/gADIpZkMFg
Please enjoy our published article on the mechanistic basis of Vaccine-induced Immune Thrombotic Thrombocytopenia (VITT) and the corresponding commentary in BLOOD #Corona #AstraZeneca

[Thomas Renné @thomas_renne]

It is well known that factor XII has a critical role in thrombosis sparing hemostasis, however the protease has much broader importance. Thanks to Reiner Mailer and colleagues for providing an update on factor XII-driven vascular inflammatory reactions:
https://t.co/qMYuFS68nm

[Thomas Renné @thomas_renne]

Mechanism of VITT
In a collaborative effort with Andreas Greinachersr team and many colleagues we have identified the mechanic basis that underlies Vaccine-induced immune thrombotic thrombocytopenia (VITT). The findings will improve patient safety. Enjoy!
https://t.co/gADIpZkMFg

[Thomas Renné @thomas_renne]

How clotting starts.
Please see our new study on the structure of factor XII activation and its diagnostic implications leading to improved patient care. Enjoy!
https://t.co/I8uTx8IbeL
https://t.co/9xT0lkAAku

[Thomas Renné @thomas_renne]

Mechanism of AstraZeneca-associated thrombosis

https://t.co/tsbVvM8eRf

[Thomas Renné @thomas_renne]

Xenotropic and polytropic retrovirus receptor 1 regulates procoagulant platelet polyphosphate | Blood | American Society of Hematology https://t.co/PuTMncwDf2

[Thomas Renné @thomas_renne]

NETs/Factor XII axis in COVID-19. antibody CSL312 might offer a novel therapy in Corona patients. https://t.co/8nO0FrkdsK

[Thomas Renné @thomas_renne]

For platelet and coagulation reseacher, please see the new study on platelet polyP: https://t.co/hJLr5z3Uko