@openanesthesia Continue with the case after asking the mother to elaborate more. . Sometimes this kind of breathing pattern is common in newborns and is benign.
just a reminder that 1y cardiac mortality is significantly higher when using TIVA in cardiac surgery
40 of 2,668 [1.5%] vs 23 of 2,685 [0.9%] p = 0.03
link to the evidence
https://t.co/6T6mWGdDSm
Here's a video I made breaking down this incredible case of a 60-year-old man who presented to the ER with a muffled voice, difficulty breathing, and coughing up blood
#FOAMed
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This is really fascinating since we often think of ketamine as being hemodynamically neutral, however, ketamine itself is a direct myocardial depressant. This is usually offset by the adrenaline release it stimulates.
-Overall, when compared to etomidate, there was a strong trend towards ketamine being associated with peri-intubation hypotension (OR 1.38, 0.99-1.94)
-Among prehospital studies there was a similar albeit pretty weak trend (1.76, 0.72-4.33)
-Among RCTs only another pretty weak trend (OR 1.43, 0.37-5.49)
However, it's worth noting a few things:
-The number of RCT's is relatively low on the topic. The RSI trial, which is underway now, will probably give us a much better answer.
-A lot of this was observational data, and based on other subanalyses it appears that this is much more pronounced among patients with pre-existing signs of hemodynamic instability (probably catecholamine depleted) before induction and less so among those without pre-existing hemodynamic instability.
I will continue to reach for ketamine for RSI, pending the results of the RSI trial.
https://t.co/fcK0EEdoOv
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