Novartis announces topline data from Phase III trial of complement inhibitor in paroxysmal nocturnal hemoglobinuria (PNH) – a rare and serious blood disorder #NovartisNews
Paroxysmal nocturnal hemoglobinuria (PNH) is a rare blood disorder that heavily hinders patients’ quality of life, and may be associated with significant barriers to care - from diagnosis to treatment. Learn more about our research in PNH https://t.co/HZGWJgk9kV. #PNH
No improvement in PFS with fulvestrant-palbo
over letrozole-palbo among patients receiving
frontline systemic treatment for endocrine-sensitive, HR+HER2- MBC. NSAI are preferred partner in this setting. The phase II PARSIFAL study published on @JAMAOnc https://t.co/W4ztxiuDV3
To improve human health, we must also protect and improve the health of our planet. @Novartis is proud to be part of the #RacetoZero—the world’s largest alliance of non-state actors committed to halving emissions. https://t.co/OEQIlW1aDH
Actualizacion en ESMO del estudio Monaleesa-2. El ribociclib aumenta la sobrevida global mas de un año. En Uruguay se mantienen los problemas de cobertura y acceso a este farmaco. Debemos trabajar por una solucion.
#ESMO21@myESMO Exciting to our field of #oncology to see the median survival improve to >5 years in both hormone sensitive breast cancer (ribociclib MONALEESA-2 data) and hormone sensitive prostate cancer (PEACE-1 data).
I wish more doctors would prescribe Kisqali/ribociclib instead of jumping to Ibrance. I'm on cycle 53 (4 and 1/2 years) of Kisqali and it's my first line of treatment since diagnosis.
The first report of a median OS exceeding 5 years in a phase 3 trial for advanced #breastcancer comes from the MONALESSA-2 trial with ribociclib and letrozole. https://t.co/DNPifEfY8r #ESMO21
First report of median survival surpassing 5 years in metastatic HR+/HER2- breast cancer with ribociclib/AI! - Dr. Hortobagyi
To our patients living with MBC, this is still not enough, but continued incremental improvements help.
@OncoAlert#bcsm@myESMO
⭐️🚨 The @myESMO#ESMO21 Sunday morning breaking news slide👉🏼MONALEESA-2: RIBOCICLIB + AI in 1L postmenopausal patients by our @MDAndersonNews legendary researcher in breast cancer -Dr. Gab Hortobagyi.
👉🏼At a median follow-up of 80 months. OS curve of the day ! @OncoAlert
CDK4/6 inhibitor Ribociclib plus endocrine therapy (letrozole) improved the overall survival in the first line setting for ER+ HER2- #MBC patients. We can now tell our patients "OVER 5⃣ YEARS" #ESMO2021 Dr. Hortobagyi #bcsm
🚨⭐️ Sunday @myESMO#ESMO21 highlight 📢 From @MDAndersonNews own legend Dr. Gab Hortobagyi➡️The MONALEESA2 trial with CDKi inhibitor
👉🏼AI +/- ribociclib for 1L metastatic HR+ breast cancer
👉🏼Improvement in OS (63.9 mo vs 51.4 mo, HR 0.76)
✅OS now exceeds 5 yrs! @OncoAlert
Monaleesa-2: AI +/- ribociclib for 1L metastatic HR+ breast cancer. Improvement in OS seen (63.9 mo vs 51.4 mo, HR 0.76); OS now exceeds 5 yrs!
@myESMO@OncoAlert
La combinación de ribociclib, inhibidor de ciclo celular a nivel de CDK4/6 y ciclina D1 (Novartis, Kisqali), con fulvestrant, degradador del receptor de estrógeno, mejora la supervivencia de mujeres postmenopáusicas con cáncer de mama metastásico HR+/HER2-
https://t.co/Z5ipuMeiTS
Almost 20 months delay in starting chemo in ER positive metastatic #breastcancer by adding ribociclib to fulvestrant - median overall survival improvement of 12 months in 56.3 months follow up @OncoAlert #ONCOALERT#ASCO21
Slamon ML3 @asco21 ribo fulvestrant improves OS in first and second line setting. Remarkable progress in most common BC subset. Imp to keep in mind that E sensitivity is not comparable in 1st line vs heavily pretreated @oncoalert