🔴 tohmes

👎: #LongCovid #Aerosol #B117 #P1 #B1351 #B16172 #E484K
👍: #BildungAberSicher #NoCovid
🏆: Rostock OB @ClausRuhe #Madsen. Durch Winter bis März '21 Inz < 54

[🔴 tohmes @tohmes1]

1/7 SARS-CoV-2 & rapid loss of acquired immunty

a follow up of the 🧵, that posits:
* GI tract persistence
* leads to long-term SARS-CoV-2 exposure in liver
* there induces peripheral immune tolerance
* which leads to percieved rapid waning of immunity
https://t.co/dAcLb2L7BM

[🔴 tohmes @tohmes1]

1/11 SARS-CoV-2 & rapid loss of acquired immunity:

a 🧵 collecting various papers & results leading up to an idea:

rapid waning is
* actually chronic antigen exposure of a persistent SARS-CoV-2 infection
* leading to depletion/exhaustion of
* SC2 acquired immune memory

[Yishan @yishan]

I contend that all or most of the recent bullshit we’ve been seeing is a downstream effect of allowing covid infection to run rampant with no attempts at mitigation.

Repeated infections of Covid, even mild or asymptomatic, lead to neurological dysfunction, often manifesting as brain fog (e.g. “can’t remember the right word”) or overlooking small errors.

People make small errors all the time, but organizations responsible for critical functions develop process-based ways to mitigate them: usually safety checklists, redundancy, cross-checking, etc.

Such processes assume a certain error rate. Example: if a typical human makes errors 2% of the time, you can use a redundant process with two humans to reduce the error rate to 0.04%. You assume an error rate based on past performance, and then add some margin of error. This margin is always finite, because the process adds cost (time or money), so you can’t have an infinitely safe redundant process.

When the base error rate goes up, some of these error-mitigation processes fail, and errors will slip through the process.

In public, these errors manifest as “how could they be so stupid as to let this happen?”

Person A makes an error, Person B was supposed to check their work, Person C was supposed to inspect them, and Person D oversees the whole thing but didn’t notice. Usually these setups successfully do that they’re supposed to.

When they fail, you get things like:

- random parts falling off of airplanes (safety checklist items overlooked)
- security teams failing to secure a nearby rooftop (thinking you told the local cops to cover it)
- IT security companies pushing out an update file filled with zeroes (engineer peer review overlooked)

These events will likely continue until COVID is decisively eradicated or it somehow mutates into an actually-harmless strain.

The former is unlikely for as long as many people continue to disbelieve that it’s a problem, and the latter is also unlikely for epidemiological reasons, despite an incorrect popular belief to the contrary. In fact, both of the above appear to be trending in the opposite direction.

How do you mitigate this individually? It sucks, but you must build additional redundancy into your own daily life to become resilient to such failures.

Add redundancy to your key services (e.g. home power), over-provision any consumable supplies (food, medicine), double-check your doctor or pharmacist’s work, and definitely avoid flying on Boeing aircraft.

I don’t drive very much, but my friend in the insurance industry tells me that accident rates are going up, so be more careful on the road.

There’s probably a lot more that I can’t think of, because like you, I’m used to our society “just working.” But that’s due to people having developed reliable business, medical, and safety processes over many years to ensure that - but now their basic error rate assumptions are starting to break.

The key idea is to realize how many people the goods and services your life depends on (“supply chain”), and assume more of those people are going to make mistakes. Very few of them are malicious, but many more of them will be incompetent.

Prepare accordingly.

[Arijit Chakravarty @arijitchakrav]

Welp.

There it is. This is a strong epidemiological signal.

[Sass @sasswashere]

Last time we saw Kapsosi’s sarcoma do this-HIV/AIDS crisis correct? We don’t have a rise in HIV.

AIRBORNE SARS2 however IS behaving “eerily similar to HIV” per HIV researchers correct? Airborne SARS2 uncontained criminally active, BILLIONS, so far, including ALL YOUTH? UNSAFE?

[Sass @sasswashere]

Is this enough evidence yet or

[Yaneer Bar-Yam @yaneerbaryam]

Breakthrough study: COVID-19 reactivates dormant breast cancer, triggering deadly metastasis (shown in mice). In humans, cancer survivors who got COVID had 4.5× higher cancer-related deaths—and 1.4× greater breast cancer.

https://t.co/sfqlon6EI6

[Harry Spoelstra @HarrySpoelstra]

Thymidine phosphorylase promotes SARS-CoV-2 spike protein-driven lung tumor development

🚨So, there you have it AGAIN, what if the lingering damage from COVID-19 isn't just “long COVID”..... but also a hidden driver of LUNG CANCER?

➡️New very interesting USA/Israel study reveals the SARS-CoV-2 spike protein ramps up thymidine phosphorylase (TYMP), fueling lung injury, fibrosis, and tumor growth, especially in smokers:

“SARS-CoV-2 SP drives lung injury, fibrosis, and tumorigenesis through a TYMP-dependent mechanism involving STAT3 signalling and inflammatory microenvironment remodelling.”

“COVID-19 significantly increases lung cancer risk, especially in current smokers.”

“TYMP represents a potential therapeutic target to mitigate long-term pulmonary consequences of COVID-19.”

‼️In conclusion, according to this study, COVID-19 isn't over when the virus leaves, it may be planting the seeds for lung cancer, and blocking TYMP may be the key to stopping it. Meanwhile, preventive post-Covid-19 monitoring is a must, especially with smokers!
#AvoidSars2 #AvoidReinfections
https://t.co/z1iUb8z71r

[🍁KayElle N 95+ @KayElleTweets]

SARS-CoV-2 infection heightens the risk of developing HPV-related carcinoma in situ and cancer

Covid is oncogenic.
https://t.co/MaqBcHEWQm

[Dr Peter Beaver 🇵🇸 @PeterJBeaver]

The SARS-2 virus can infect 32 organ tissue types in foetuses via amniotic fluid, damaging DNA & immunity.

Viruses were evident in 9.1% of foetal samples from infected mothers. Highly evident in 3.9%. Only 2 of 18 foetuses showed no signs of infection.

https://t.co/tUi9mejGpM

[CoronaHeadsUp @CoronaHeadsUp]

France: A baffling "explosion of cancers"

“We’re seeing a dramatic increase in pancreatic cancer without the slightest idea why. Did something happen? We don’t know. The whole world, the entire global cancer community, is asking itself this question. The system that allows us to understand cancer is failing us.”

"Scientists say they can find no rational explanation"

Debout La France
https://t.co/qyg5lke35C

[Ilkka Rauvola @jukka235]

Infection with a virus that can cause cognitive issues and significant long-term health problems is being normalised.
2/x

https://t.co/QCeaQcVOEU

[BirdieBittern @BirdieBittern]

My post 4 hours ago⬇️

Researchers at UVA School of Med found that serious viral infections {Covid, flu, pneumonia}

"reprogrammed" immune cells in the lungs to facilitate the growth of cancer tumors months or even years later

Connect the fucking dots🙄
https://t.co/kQvPBEOvdL

[Dara in Chains @DarainChains]

Here is a big post about every cell SC2 infects in the body that we know of so far.
## Comprehensive Overview of SARS-CoV-2 Receptor Locations
Why can't we just worry about the spike protein?

SC2 binds to various receptors across multiple body regions, allowing for entry into diverse cell types. Here’s an expanded list of the receptors, their associated cell types, and specific anatomical locations throughout the body, including the brain and major organs.

1. ACE2 (Angiotensin-Converting Enzyme 2)
- Cell Types:
Epithelial cells, endothelial cells
- Locations:
- Lungs:
Alveolar type II cells
- Heart:
Cardiomyocytes
- Kidneys:
Proximal tubular cells
- Intestine:
Enterocytes in the small intestine
- Blood Vessels: Endothelial cells lined in arteries and veins
- Testes:
Leydig and Sertoli cells
- Nasal Epithelium:
Ciliated epithelial cells
- Mouth and Throat:
Oral epithelial cells

2. TMPRSS2 (Transmembrane Protease, Serine 2)
- Cell Types:
Epithelial cells
- Locations:
- Lungs:
Respiratory epithelial cells
- Prostate:
Prostate glandular cells
- Intestine:
Enterocytes of the small intestine
- Pancreas:
Ductal cells

3. Dipeptidyl Peptidase 4 (DPP4)
- Cell Types:
Immune and epithelial cells
- Locations:
- Lungs:
Epithelial cells
- Pancreas:
Islet cells (β-cells)
- Kidneys:
Renal tubular epithelial cells
- Heart:
Cardiac fibroblasts
- Brain:
Neuronal cells

4. Neuropilin-1
- Cell Types:
Endothelial and neuronal cells
- Locations:
- Lungs:
Vascular endothelial cells
- Brain:
Neurons and glial cells (including astrocytes and oligodendrocytes)
- Heart:
Cardiomyocytes
- Intestine:
Intestinal epithelial cells

5. Heparan Sulfate
- Cell Types: Present on diverse cell types
- Locations:
- Lungs: Epithelial and endothelial cells
- Blood Vessels: Endothelial cells throughout the circulatory system
- Brain:
Neurons and glial cells
- Muscle:
Skeletal muscle cells
- Skin:
Dermal fibroblasts

6. Furin
- Cell Types:
Various human tissue cells
- Locations:
- Lungs:
Epithelial cells
- Brain:
Neuronal cells and glial cells
- Heart:
Cardiomyocytes
- Pancreas:
Exocrine pancreatic cells
- Intestine:
Enterocytes

7. CD147 (Basigin)
- Cell Types:
Various cell types
- Locations:
- Lungs: Epithelial cells
- Brain:
Neuronal cells
- Heart:
Myocardial cells
- Immune System:
T cells and macrophages throughout the body

8. KREMEN-1
- Cell Types: Developing tissues
- Locations:
- Embryonic tissues:
The exact roles in adult tissues are still under investigation.

These receptors and their distribution across various organs, including the lungs, heart, kidneys, intestines, brain, and skin, contribute to the wide-ranging effects of SC2 infection and its potential complications in multiple systems throughout the body. So while vaccine injury is happening, it's only to do with 1 type which is the Spike2.
Next let's look at megakaryocytes and why that is important in LC.

[Denis - The COVID info guy - @BigBadDenis]

Study: "SARS-CoV-2 causes lasting immune dysregulation for over 20 months"

Large multicenter study finds SARS-CoV-2 exposure causes long-term immune changes affecting CD4+, CD8+, NK, and total T cells, persisting up to 20 months.

Source: https://t.co/1Bn0mcZquE

[Jesse Morse, M.D. @DrJesseMorse]

Huge new study finding from COVID.

20 months after infection “In cardiovascular disease patients, T lymphocytes remained 72.9% below baseline for 20 months post-infection.”

That’s absolutely insane. A 73% persistent drop in the body’s ability to fight infections.

This includes your ability to fight cancer…

[James Throt MBBS, MD, PhD, FRCPath @JamesThrot]

Frontal lobes refine behaviour. COVID damages them.

They regulate impulse control, empathy, moral reasoning & judgment.

Damaged lobes mean someone can remain articulate & knowledgeable while becoming reckless, cruel, suggestible & catastrophically bad at evaluating consequences

[🔴 tohmes @tohmes1]

connect the dots

[Jammer @acrossthemersey]

A little over 3 years ago, a Phd Economic Researcher for the Federal Reserve of New York started tracking this and suggested that it would continue if nothing changed in addition to other factors like aging etc.

[🔴 tohmes @tohmes1]

Sweden.
connect the dots...

[Ilkka Rauvola @jukka235]

Deaths of 5-9 year olds in Sweden.
1/x

[PACO @PacoOnPause]

It will never make sense to me that so many people are not making an effort to prevent being reinfected by a virus that keeps being linked to neurodegeneration.

A mask is slightly inconvenient. Neurodegeneration is very inconvenient.

[Jon Douglas @atranscendedman]

Boston College researchers reviewed 33 studies with over 53,000 adults and found that at least 8% developed new-onset diabetes after COVID-19 infection.

Most cases were type 2 diabetes, while type 1 remained rare.

https://t.co/gBz6gRCEnd

[CoronaHeadsUp @CoronaHeadsUp]

Spain: “Never before in Spain have so many cases of cancer been diagnosed, especially in young people."

In 2026, an estimated 300,000 new cases are expected: colon, breast, lung and prostate.