Our porcine deltacoronavirus paper is now online @NatureComms π
https://t.co/R0DYYesH5P
A huge congrats to co-first authors @du_wenjuan/@toniak_o, and everyone else who contributed.
This was another great collaboration with the Bosch group - stay tuned for the next one!
Interested in emerging zoonotic viruses are you? Did you like the film βbabeβ?
Then check out the Preprint of the work Wenjuan, I & many others contributed to. I told a porkyπ· there isnβt actually anything about babe, but there is a lot about a human infecting pig coronavirus
Excited to share our first preprint of 2024! π
π https://t.co/nQCuWw4wAl
This study focuses on PDCoV, an emerging enteric pathogen.
We generated anti-spike mAbs & investigated their inhibitory mechanisms using structural & functional studies (π§΅).
#virology#cryoEM
Can SARS-CoV-2 be transmitted via virus-contaminated hands?
In our letter to the editor of @CMIJournal, we fill in another piece of the puzzle regarding indirect transmission. (π§΅)
Excited to see my first, first-author publication online:
https://t.co/HNL8cXQOiX
#SARSCoV2
Our preprint is available on @biorxivpreprint ! If you interested in myosin-5a β , simulating pseudo-atomic models from low res cryo-EM data β , and/or gaining physical properties from cryo-EM data β please give it a read!!
How can you convince a coronavirus to share its cell entry secrets?
Give it something sweet! π¬
Using #cryoEM & MD, we show how a sugar-based receptor binds to the HKU1 spike and triggers opening via an allosteric mechanism (π§΅).
https://t.co/Jsm61GjTk8
#glycotime#virology
Greatly enjoyed the third installment of the "Snurdiss" meeting! We had fantastic talks from @toniak_o and @TShamorkina! Ollie demonstrated very nicely how cryoEM can contribute to veterinary medicine research!
Our latest research is now online @FrontImmunol!
@du_wenjuan et al made a hexavalent biparatopic HCAb targeting the SARS-CoV-2 spike.
This molecule neutralised multiple VOCs, whereas the parental HCAbs lost potency.
Congrats to everyone involved!
https://t.co/zyuEQdEs3J
Sypke did a great job presenting his mini project results today! Under the watchful eye of @toniak_o, he has been testing how well ModelAngelo does on several unpublished maps from our lab (including one he processed himself). Good luck with your next MSc internship in Barcelona!
Very excited to finally be able to share the details of our work on finding a peptide with broad action against coronavirus infection (including SARS-CoV and multiple variants of SARS-CoV-2!).
https://t.co/BmTz5nSVI1
Are you looking for a new role to put your #cryoEM skills into action? Join our life science cryo-TEM application team and be the first one to use the latest technology! π¬π³π±
Happy to answer questions π
Please RT π
https://t.co/G7yY9QGf0B
So happy to see this online!
It has been a privilege to work with @MolecularPrtnrs (and many others) over the last two years to develop ensovibep, a first-in-class antiviral DARPin to treat COVID-19 π
Congratulations to everyone involved!