NQX

Neurocirugía. Neurotrauma. Neurosurgeon. México.

[CNS @CNS_Update]

The Skull Base Fellows Course is a premier course offering hands-on experience for all attendees with lectures from our expert faculty. Join us August 28-29 in Cleveland—registration is now open, so reserve your seat today: https://t.co/bfvJX3nNtp
#CNSCourse #skullbase
@CNSResidents

[James Rutka @JamesRutka]

New Neurosurgical Focus issue, open access, all free, depicting methods to manage CSF leaks in neurosurgery! @thejns.org

[Michael Okun @MichaelOkun]

What did the newest large antibody trials for Alzheimer's disease just published @NEJM reveal? There were two large phase 3 trials of Gantenerumab for early Alzheimer’s. Survey says: NEGATIVE, did not meet primary outcome variable. Let's discuss and think about WHY?
Key points:
- Gantenerumab actually led to partial removal of amyloid plaques.
- It improved some soluble biomarkers of Alzheimer’s.
- Magnitude of amyloid plaque removal 'smaller than expected' especially head to head with prior smaller trials on this drug.
- Interestingly, the mean amyloid level on PET remained elevated; only 1/4 reached amyloid-negative status.
- The author's hypothesize that rapid plaque reduction, could have been below detection threshold.
- They wonder if the time frame needed to be longer?
- Higher incidence of ARIA-E.
- Gene status mattered: homozygous carriers APOE ε4 more likely to get ARIA-E when compared to heterozygous carriers or noncarriers.
- They tried a dose-escalation scheme to limit the increase in ARIA-E and it did not seem to work.
- My take: Persons with #Alzheimers and neurodegenerative diseases are understandably anxious for clinical trials and this agent was underwhelming. We did learn some things from this trial, and it is important we put compounds to the ultimate test in randomized controlled studies. This antiamyloid antibody gantenerumab didn't slow decline in cognitive function in early Alzheimer’s. For those watching from afar Lecanemab is still on top of the hill for this approach.
https://t.co/r4zf5VIonM

[James Rutka @JamesRutka]

On the cover @TheJNS for August 2023, new technique for expansive cranioplasty especially useful in decompressive craniectomy for stroke and trauma! https://t.co/9MiBEO5nKH

[James Rutka @JamesRutka]

Everything you ever wanted to know about the management of brain metastases, and more! Now in latest issue of NS Focus for @TheJNS ! https://t.co/ZSmENdMJD0

[Maciej M Mrugala, MD, PhD, MPH, FAAN @MrugalaMaciej]

Amazing work from @savora and colleagues from @MayoClinicME

[Chicago Symphony Orchestra @chicagosymphony]

A season-long celebration of Rachmaninov’s 150th birthday continued on Thursday as @daniil_trifonov joined the Chicago Symphony Orchestra for a performance of the composer’s mammoth Piano Concerto No. 3, exhibiting incredible virtuosity and endurance.

📷: @toddrphoto

[Brain Injury Assoc. @biaamerica]

Each brain injury is unique and every survivor will experience different symptoms as the result of their injury. Concussions are one of the most common forms of brain injury, so it's important to know what signs and symptoms to look for. Learn more here: https://t.co/H0rDgOXPxA

[Oren Gottfried, MD @OGdukeneurosurg]

Schematic overview of the cerebrospinal fluid system. What can you tell me about CSF? 🧵

[NASBS @NASBSorg]

#JNLSB_Highlights
Anatomical Step-by-Step Dissection of Complex Skull Base Approaches for Trainees: Surgical Anatomy of the Retrosigmoid Approach
#nsgy ##retrosigmoid #training #neuroanatomy @graffeo @MayoClinicNeuro @MichaelJLinkMD @PerisCelda
Text: https://t.co/5WspsQnw7D

[Abu Shanab @med_712]

How take reflexes in 30 seconds

[NQX @traumabrainmex]

@OGdukeneurosurg OMG

[Pediatric Imaging @pedsimaging]

Former premature newborn, now 1 month old with seizures

Coronal US (above) shows dilated ventricular system that contains complex echogenic fluid. Axial CT (below) shows dilated ventricular system that contains complex fluid

#FOAMed #FOAMPed #FOAMRad #PedsRad #RadEd #RadRes

[Nader Dahdaleh @NaderDahdaleh]

Spine case du jour: 60, F, neck pain, progressive myelopathy (UE: 3/5, LE: 4/5). BMI 14 (eating disorder), osteoporosis.
Diagnosis? Treatment strategy?

[ZATlatelolco INAH @ZA_Tlatelolco]

#BuenosDías #FelizJueves
🖨✂🖍️🙃😁
Continúa con tu #Colección de #Dioses del #Panteón #Mexica
#Descarga las imágenes, #colorea y #diviértete con la sopa de letras
#XipeTótec
#TlatelolcoMásAlláDeLosTiempos
#QuédateEnCasa estamos #ContigoEnLaDistancia
#CulturaDesdeCasa

[Oren Gottfried, MD @OGdukeneurosurg]

Please explain this drainage at the external ear canal? #neurosurgery #ent #skullbase #neurology #neurotwitter #nature #science #healthcare #trauma #ears

[SNO @NeuroOnc]

View the Brain Metastases module on the Neuro-Oncology Academy. The module provides lectures that focus on the most common primary malignancies that metastasize the brain and leptomeninges. All SNO learning modules are free of charge. https://t.co/m9AXtF6UYY #neurooncologyacademy

[Oren Gottfried, MD @OGdukeneurosurg]

A Slide to Save: Every time you assess a lumbar mri for any indication, look for the possibility of a tethered cord w/ any conus extending below L2 mid body. It may be more occult than these w/ fatty filum. You’ll need to adjust your workup & surgical plan accordingly.

[JM Alcalá @piper_tazo]

ICH signs
increases the likelihood of hematoma growth in the first hours

CT
(1) Black hole sign
(2) Island sign
(3) Blend sign

CTA
(4) Spot sign

Source: @StrokeAHA_ASA @GreenJournal @Radiopaedia