Depression, anxiety, and ADHD all have documented links to impaired folate metabolism.
The same MTHFR variants that affect ~40% of the population - and can't properly convert synthetic folic acid - also impair serotonin synthesis capacity.
From late 2026, we're adding the form they can't convert to every loaf of bread.
I wrote about the mechanism - from gut dysbiosis through inflammation to tryptophan diversion - here:
https://t.co/mLPp1ervxL
#MTHFR #Depression #FolicAcid #Methylation #GutHealth #TestDontGuess
Multiple studies have found associations between high folic acid supplementation and increased prostate cancer risk.
A randomised trial (Figueiredo et al., JNCI 2009) found men taking 1mg/day synthetic folic acid had nearly double the prostate cancer incidence of the placebo group over 10 years.
We are about to add folic acid to the diet of every man in the UK. Involuntarily.
Around 40–60% of the UK population carries a variant in the MTHFR gene.
This variant impairs the conversion of synthetic folic acid into the active form your cells can actually use (5-MTHF).
Result: unmetabolised folic acid accumulates in the bloodstream.
This is not a theoretical concern.
@zoeharcombe BMJ Study
“folic acid could contribute to a higher probability of contracting clinically detectable infection with SARS-CoV-2 and to an increase in the risk of death following the infection.”
https://t.co/aZiavr9Py1
@DrHoenderkamp would you please ask your followers to sign this petition to stop white flour being fortified with Folic Acid. Many of us should not be consuming it. https://t.co/jDtykXB1im
Around 2.3 million people in the UK are living with CHD (the main condition leading to stents). Many of these will have had PCI/stents. If you know anybody with a stent please tell them to avoid products containing Folic Acid to avoid having to have another stent.
Lets just add some detail on synthetic Folic Acid being added to all flour debate thats raging. Many people had no idea it was happening and many more people didn't want it at all. So how did it happen?
You should know that your MP did NOT get the chance to vote on this legislation, even if you contacted them about it. ohhh no. It was decided by 3 quangos (The Bread and Flour (Amendment) (England) Regulations 2024, SI 2024/1162) and based on UN and WHO nutrition targets under Agenda 2030 sustainable development goal 3. The policy chain looks like this:
UN/WHO nutrition targets are set by this unelected global body, then ...
⬇️They issue global food-fortification guidance
⬇️UK advisory bodies such as SACN/FSA
⬇️ Ministers
⬇️Statutory Instrument
🟰mandatory change to the national food supply.
And yes, the WEF promotes “food-system transformation” and nutrition interventions. WEF material has positively references flour fortification with iron, folic acid and vitamin A and talks about reshaping food systems for health, resilience and sustainability.
Does that sound like democracy to you? or does that sound like global decision making?
When the state changes the composition of everyday food consumed by millions of people, that should be done through a full Act of Parliament, with proper debate, scrutiny and accountability. It hasn't been.
Lots of people worried about finding flour that is folic acid free.
Especially cancer patients and those with heart stents.
But look at this thread.
The problem is WAY bigger than just flour.
Folic acid to be added into UK food supply. Folic acid more than doubles risk of prostate cancer. The NIH warns cancer patients to steer clear of folic acid. Any of this making sense?
It really is in everywhere.
Here are some foods you might think could be freely eaten if you are avoiding foritfied flour.
But they all have folic acid in them.🧵
Duchy "organic" sausages:
I have spent most of my life in lincolnshire and am trained in horticulture and arboriculture and can confirm current practices of net zero and the over ruling of local planning and their own guidelines for agricultural land are nearly as bad as nuclear contamination because of the decades recovery time needed if it was all stopped and removed now
I’m a lifelong environmentalist, but net zero is a crass logic solution that creates bigger problems. We should be focusing on ecosystems, farming, photosynthesis and pollution reduction to ‘save the planet’ rather than the corporate virtue con trick of net zero.
“What’re you in for mate?”
“Cleaning a river without a permit. What about you?”
@EnvAgency is really plumbing new depths of malevolent uselessness here.
Unelected and unaccountable Quangos are out of control.
Volunteers removed 200 bags of rubbish from a river after years of neglect, pollution and fly tipping.
So the Environment Agency’s threatened to prosecute them! Idiots.
“We won’t clean it and you can’t either” 🤡
Dartmoor's hill ponies have grazed those commons for longer than there has been a country called England. Fewer than a thousand are left, down from six thousand a generation ago. The United Nations listed them as endangered in 2023. So, naturally, the body charged with protecting nature has decided to get rid of nine in ten of the survivors.
There is a process, obviously.
Natural England's new grazing contracts now count the ponies in the same bucket as the cattle and sheep. A commoner with a fixed quota has a choice: keep a semi-wild pony worth nothing at market, or use the slot for a lamb he can sell. Guess which one survives the spreadsheet. The rest are gathered in the autumn drifts, and with nowhere to put thousands of unhandled moorland ponies, the next stop is the abattoir.
Natural England would like it noted that it has not ordered a cull. It has merely built a machine whose only output is a cull, switched it on, and handed the bolt gun to a farmer so the fingerprints land elsewhere. Very tidy.
And now the funny part. The pony is the best tool on the entire moor for eating Molinia, the coarse purple grass strangling Dartmoor into a brown monoculture. Cattle and sheep won't touch it. The ponies hoover it down and clear the ground for the orchids, the wildflowers and the insects behind them. Remove the ponies and the moor chokes into precisely the lifeless scrubland the contract was meant to prevent.
So the conservation strategy, in full: protect the habitat by deleting the animal that maintains the habitat. A masterclass.
Better still, Natural England's own Fursdon review looked at this exact question and told them, in plain English, not to lump ponies in with cattle and not to cut pony numbers. They read it, praised it, said they fully supported it, then did the precise opposite.
Four thousand years these animals have run Dartmoor with no committee and no contract. They could be gone within one, and the people who did it will write it up as a win for nature.
Scotland 🏴
Research by Action to Protect Rural Scotland has claimed that if all 16 large data centres currently in planning went ahead, their energy use would be 1.5 times greater than peak winter demand for the whole of Scotland.
This is insane.