Txell Genescà

mucosal immunologist, infectious disease researcher at Vall d’Hebron Institut de Recerca (VHIR)

[Txell Genescà @TxellGenesca]

Overall, we show that SARS-CoV‑2 entry is governed by distinct, organ‑specific repertoires of host factors, rather than a universal ACE2-TMPRSS2 axis. With @hoheyn @mariajosebuzon1 and many other collaborators!

[Txell Genescà @TxellGenesca]

Check out our new preprint Site-Specific Entry Factors Define Cellular Susceptibility to SARS-CoV-2 in Human Tissues https://t.co/j02FeRa2qF, a collaborative effort between researchers from @VHIR_, @vallhebron, @cnag_eu & @BSC_CNS
Thanks to everyone involved!

[Txell Genescà @TxellGenesca]

We found ADAM17 and IL1R1, together with canonical molecules, to significantly facilitate viral entry in the lung parenchyma, while entry into the renal cortex was less dependable on canonical factors, but strongly modulated by JAK1/2 engagement.

[Vall d'Hebron Institut de Recerca @VHIR_]

@vallhebron @la_marato La Dra. @TxellGenesca, IP del grup de Malalties Infeccioses del #VHIR, explica els resultats del treball al pòdcast de la revista científica @MucosalImmunol

Escolta-ho aquí 👇 
https://t.co/Kv9erehtcu

[Txell Genescà @TxellGenesca]

Thanks for highlighting our work!

[Mucosal Immunology @MucosalImmunol]

#MucosalMonday means a new podcast episode with @societymucosalimm - catch the latest discussions, mysteries, and the latest research at MI! https://t.co/sdx15nIKTY

[Txell Genescà @TxellGenesca]

Check out our study where we identify IL-1β–stimulated PMN-MDSCs as immunosuppressive mediators in female genital tract infections, potentially modulating susceptibility to local secondary infections. Thanks to everyone that participated @DaanPieren @la_marato

[Mucosal Immunology @MucosalImmunol]

Cervical mucosal inflammation expands functional polymorphonuclear myeloid-derived suppressor cells in this work from @DaanPieren @TxellGenesca and colleagues at @VHIR_ https://t.co/L2B66lJSZM

[Txell Genescà @TxellGenesca]

Thrilled to share our latest preprint where we reveal the benefits of ex vivo inducing CD8+resident memory-like phenotypes as a promising immunotherapy to control rebound viruses and eliminate persistent antigens like HIV-1.
https://t.co/JJgF7qujVJ
#mucosalImmunology  @VHIR_

[Txell Genescà @TxellGenesca]

On the move to @txellgenesca.bsky.social

[Vall d'Hebron Institut de Recerca @VHIR_]

. @la_marato finança set projectes de @vallhebron en salut sexual i reproductiva, els quals s'han avaluat en funció de la seva qualitat i metodologia, rellevància científica, sanitària i social, i valor innovador i transformador.

Descobreix-los tots:
https://t.co/y93XcQILoZ

[Mackay Lab @LMackayLab]

1/ 🚨 Hot off the press! 🚨Our new paper, led by @ObersAndreas & @maxevrard, is now live in @ImmunityCP! 🧬 Curious how CD8+ tissue-resident memory T cells (TRM) adopt their fate in different organs? Let’s dive in! 🧵👇
https://t.co/vcgpgMgBcZ

[Txell Genescà @TxellGenesca]

Thankful to be part of this ! Keep it up!

[CaixaResearch @CaixaResearch]

@ignasilopezv @FundlaCaixa @FundlaCaixaPT ¡Así finalizamos la tercera edición del #CaixaResearch Health Meeting!

Ha sido un honor compartir estos días llenos de networking, ideas innovadoras y debates enriquecedores.

Nos llevamos mucha inspiración para el futuro. ¡Gracias a todas y todos por hacerlo posible! 🚀💙

[Txell Genescà @TxellGenesca]

Mucosal inmunologists enjoying the fantastic ECI 2024 meeting in Dublin !! @socmucimm @ejvillablanca

[JCI insight @JCI_insight]

Final version out now! https://t.co/TO0qZpNhHH
Neutrophil biomarker CD15 may help identify anal cancer risk in people with HIV. Work from Joaquin Burgos and @TxellGenesca et al. @VHIR_ @mariajosebuzon1 @adriacurran

[Society for Mucosal Immunology @socmucimm]

The SMI Mentorship Program participants connected this morning at #ICMI2024. Interested in the program? Learn more on our website and watch for applications to open in early 2025. https://t.co/Q9H6MelCQn

[Txell Genescà @TxellGenesca]

Based on pathology, we observed divergent trends in
resident lymphocyte populations and myeloid-derived suppressor cells and neutrophils.
Epithelial infiltration of CD15+ neutrophils associated to pathology provides a biomarker of interest for assisting HSIL diagnosis 2/2.

[Txell Genescà @TxellGenesca]

Enjoy the in-press preview version from JCI insight
https://t.co/4x9xcC3BJc, where we study local immunological mechanisms associated to the development of anal dysplasia 1/2. #HSIL @VHIR_ @mariajosebuzon1 @adriacurran Dr. Joaquín Burgos!

[Jakob Zimmermann @JZimmermann001]

📢OPEN PhD POSITION📢

Looking for a PhD and interested in the emerging field of mucosal immunology? Apply now to join our young and enthusiastic team in using new tools to understand how T cells are primed by gut microbes and how they become dysregulated in IBD!

Please retweet!

[Georg Gasteiger @GeorgGasteiger]

Junior Research Group Leader position: Join the Würzburg Infection and Immunology community! https://t.co/zWm8ocDIkE

[Societat Catalana d'Immunologia @SCImmunologia]

‼️ Noves ofertes laborals a la nostra web ‼️

👉 Postdoc Data Science Malaria Immunology Group (ISGlobal) @ISGLOBALorg

👉 Technical specialist in flow cytometry for the High Technology Unit (UAT) (Vall d'Hebron Research Institute) @VHIR_

🔗 Detalls ⬇️
https://t.co/Y6NJQNeUtY