Johnson McEvoy MSc, DPT, PT

Physiotherapist & post graduate lecturer & author.

[Johnson McEvoy MSc, DPT, PT @unitedphysio]

#physiotherapy #iscp #ireland

[Johnson McEvoy MSc, DPT, PT @unitedphysio]

@Simi_2210_ 100

[Johnson McEvoy MSc, DPT, PT @unitedphysio]

@daveclarkemd Very helpful and insightful
Psychosocial aspects and lifestyle medicine

The Immune Mind by Monty Lyman is a great read about immunopsychology etc

Was eye opening

[Johnson McEvoy MSc, DPT, PT @unitedphysio]

@hjluks The effect of exercise muscle immune modulation is fascinating.

Sluka’s et al work on exercise (both aerobic and strength) effect on M1 and M2 macrophahes is exciting

[Johnson McEvoy MSc, DPT, PT @unitedphysio]

@PhysioMeScience No direct diet advice?
Sleep?
Stress?

All big factors for immune, metabolic and endocrine influences

[Johnson McEvoy MSc, DPT, PT @unitedphysio]

@ArthroscopyJ @grandales_ramon Not to mention the risk before TKR or THR

[Johnson McEvoy MSc, DPT, PT @unitedphysio]

@PhysioMeScience 👍🏻 As stated, it’s important not to overstate the effect size of exercise on pain…

having said that, exercise is one of the best ways to improve overall health including metabolic and immune

[Johnson McEvoy MSc, DPT, PT @unitedphysio]

@ksluka0101 Really great book
Love the addition of your art
👍🏻

[Johnson McEvoy MSc, DPT, PT @unitedphysio]

@adamdobson123 @DrMarwanAl_D Mazza DF, Boutin RD, Chaudhari AJ. Assessment of Myofascial Trigger Points via Imaging: A Systematic Review. Am J Phys Med Rehabil. 2021;100(10):1003–1014.
PMCID: PMC8448923

[Johnson McEvoy MSc, DPT, PT @unitedphysio]

@tomgoom @Seth0Neill @pdkirwan @DrPeteMalliaras @tendonpain @TendonGlasgow @alisongrimaldi @DakinLabGroup @Physio_lab @StephLaz_ @ExploredPhysio Including Sherhans work from Harvard over 20 years ago on lipid derived mediators… specialised pro resolving mediators from OM3’s…

This work potentially could win a Nobel prize…

"No matter how we twist and turn we shall eventually come back to the cell"
Rudolf Virchow

[Johnson McEvoy MSc, DPT, PT @unitedphysio]

@tomgoom @Seth0Neill @pdkirwan @DrPeteMalliaras @tendonpain @TendonGlasgow @alisongrimaldi @DakinLabGroup @Physio_lab @StephLaz_ @ExploredPhysio Inflammation is a first principles approach to human health and MSK pain.

Mounting evidence (older and newer) that non-resolving inflammation (m1 to m2 polarisation) is a key in ongoing nociception and tissue distress.

The switching depends on many factors…

[Johnson McEvoy MSc, DPT, PT @unitedphysio]

@PhysioMeScience Interesting test and paper… commendable 👍🏻

Suspect a significant % of cohort would not be able to perform… interesting to know how many were excluded in the trial due to inability to perform?

[Kathleen Sluka @ksluka0101]

Just arrived in my office-3rd edition of my book. New chapters, my original art, patient stories, and case studies. Available in September....#kathleensluka #slukaart #painscience ⁦@UIowaPTRS⁩
⁦@uihealthcare⁩ ⁦@IowaMed⁩ ⁦@UIowaNeuro⁩

[Johnson McEvoy MSc, DPT, PT @unitedphysio]

@DissentingCat @Niek_NTe

[Johnson McEvoy MSc, DPT, PT @unitedphysio]

@PhysioMeScience With the added caveat that the effect size on pain from exercise wasn’t outstanding and that “sham” (albeit hard to define non-specific exercises as sham) had similar outcomes to specific tendon targeted exercises.

Patient expectations and beliefs play a significant role.

[Johnson McEvoy MSc, DPT, PT @unitedphysio]

@BrandonLuuMD Om3 EPA & DHA play an important role in inflammation resolution from M1 to M2 states

Resolvins, protectins and maresins
Not surprisingly they show up in these studies with positive influence

However study design is hard connect causation as you eloquently said

[Johnson McEvoy MSc, DPT, PT @unitedphysio]

@OGdukeneurosurg Crook lying position?

[Johnson McEvoy MSc, DPT, PT @unitedphysio]

@DavidPerlmutter + Omega 3 and vit D

[Johnson McEvoy MSc, DPT, PT @unitedphysio]

@Rainmaker1973 M1 Macrophage?
Innocuous until they attack with cytotoxic TNF etc

PAMP and DAMP activated

[Asaf (Klaf) Weisman @AsafKlaf]

New study finds evidence for neuroinflammation in the periphery of individuals after WHIPLASH. Very well conducted study! Sample size ✅ control group ✅ Sig. findings on MRI ✅ Sig. findings on blood tests ✅ Sig. findings on QST ✅

Seriously, the notions of “brain derived pain” without nociceptive input pain are just plain nonsense and not sustainable anymore.

[Johnson McEvoy MSc, DPT, PT @unitedphysio]

@Omid_HopeUni Infraspinatus upper part also shoulder abductor?