VanVeller Group

organic and bioorganic chemistry, peptide chemistry, photochemistry

[VanVeller Group @vanvellergroup]

@TomFiaLAB @brettvanveller @ChemicalScience More secondary structure on the way ;)

[Chemical Science @ChemicalScience]

Amidines are an isostere of the amide bond but are unexplored in peptide secondary structure.
The @vanvellergroup from @IowaStateU shows how amidines are not only tolerated in helical structures but can even enhance helical folds. #MyFirstChemSci

https://t.co/qrGyoazOv7

[VanVeller Group @vanvellergroup]

Congratulations to our 4th year grad student @emilyob51 for her acceptance into the Iowa State Graduate College Emerging Leaders Academy! 🎉 @ISUGradCollege @IASTATE_Chem

[J. Am. Chem. Soc. @J_A_C_S]

General Installation of (4H)-Imidazolone cis-Amide Bioisosteres Along the Peptide Backbone | Journal of the American Chemical Society @brettvanveller
@IASTATE_Chem #Imidazolone #Amide #Bioisosteres #Peptide https://t.co/qzv9vmBDSF

[VanVeller Group @vanvellergroup]

Congrats to Moha, Aaron, Emily, and Brendan on their well-deserved graduate student research awards!

[VanVeller Group @vanvellergroup]

@J_A_C_S

[VanVeller Group @vanvellergroup]

A rapid amidine cyclization enables insertion of (4H)-imidazolones––a cis-amide bioisostere––into peptides during SPPS – out now in JACS! 🧪
https://t.co/H65gzNmUPI

[VanVeller Group @vanvellergroup]

What can't the thioimidate do? Check out our most article in @JOC_OL on thioimidate solutions to thionopeptide deprotection!
https://t.co/SPCYzL7gUH

[VanVeller Group @vanvellergroup]

Congrats @brendanxwall, Krishna, @emilyob51, Aaron, and @brettvanveller!

[Brett VanVeller @brettvanveller]

Our department is hiring an assist/assoc prof in organic chemistry, broadly defined. #chemistry #chem #chemtwitter Please apply https://t.co/q3Gw492rVQ

[J Org Chem/Org Lett @JOC_OL]

Sulfenamides are an often-ignored functional group due to their instability. A new computational study in #JOrgChem of the α-effect for S–N nucleophiles reveals that an unusual anomeric interaction may aid their stability. From @vanvellergroup, https://t.co/P8s5JRQbDp

[American Peptide Society @ampepsoc]

SESSION 4: PROTEIN ARCHITECTURES – STRUCTURE AND FUNCTION
L20 – Brett VanVeller, Iowa State University
Thioimidates: An Obscure Functional Group Provides General Access to Peptide Bond Isosteres

[Brett VanVeller @brettvanveller]

Special moment when you get to present in the same section as your former advisor Ronald Raines at APS #peptides2023. Working on some polymer projects to complete the set with @SwagerGroup and @AdronovGroup

[VanVeller Group @vanvellergroup]

It��s award ceremony season and our lab recently celebrated grad students @brendanxwall and @emilyob51 on their @IASTATE_Chem departmental awards!

Of course they had to get a picture with Rosalind too! 🧬

[American Peptide Society @ampepsoc]

AGENDA HIGHLIGHT Session 4: Protein Architectures: Structure and Function featuring Ronald Raines, Emma Watson @Dr_EmmaWatson, Brett VanVeller @brettvanveller, Marina Rubini @TheRubiniGroup, and Jianfeng Cai. https://t.co/4axLeaqe5C
'Early bird' discount ends May 1. #Peptides2023

[VanVeller Group @vanvellergroup]

Our work on amidines in peptides is highlighted by Org. Process Res. Dev. https://t.co/W3kTpRv1D2

[ACS Synthetic Bio @ACSSynBio]

"The synthetic strategy developed in this study represents the first robust and general procedure for the introduction of amidines into the peptide backbone."

Now in @J_A_C_S, from VanVeller and colleagues @IowaStateU 

https://t.co/XUXYJJHGKN

#unnatural
#peptide
#synthesis

[J. Am. Chem. Soc. @J_A_C_S]

A General Strategy to Install Amidine Functional Groups Along the Peptide Backbone @brettvanveller @IowaStateU #Modification #Amidine #Peptide #Backbone https://t.co/U5Cbf2bMPd

[ACS Publications @ACSPublications]

Check out this ACS As Soon As Publishable (ASAP) article from @J_A_C_S: A General Strategy to Install Amidine Functional Groups Along the Peptide Backbone. Discover more ASAP articles: https://t.co/1PCafiFDSH

[VanVeller Group @vanvellergroup]

@J_A_C_S

[VanVeller Group @vanvellergroup]

Taking amidines where no amidine has gone before…linear peptides during SPPS! 🚀 @IASTATE_Chem https://t.co/yghX4KcNJV