Join us in beautiful Ann Arbor! Assistant Professor position in the Department of Computational Medicine and Bioinformatics at the University of Michigan. https://t.co/gKWJtizuz2. Please spread the word.
If you like coloc, but hate making a single causal variant assumption, check out this update now published https://t.co/EWdL7yF6Ul with the package available from CRAN https://t.co/jJ5EWB3DDI and vignette https://t.co/sWouPEk5c2.
Obesity-associated variants within FTO mediate disease risk through brain (Smemo, 2014) or adipose (Claussitzer, 2015) phenotypes?
Both!
How?
Extensive pleiotropism and allelic heterogeneity mediate metabolic effects of IRX3 and IRX5
Now out at Science: https://t.co/pnWgd6bcGf
ICYMI due to the holiday weekend! We have performed a genome-wide #CRISPR screen in human pancreatic beta-cells to identify genes which regulate insulin content https://t.co/EARWq71epp @antje_grotz @StanfordPeds@RDMOxford 1/
We’re hiring! Postdoc in regulatory genomics and statistical genetics. Single-nucleus multi-omics in pancreatic islets to detect context-specific e/caQTL and integrate with T1D GWAS. Collab with @ChenShuibing through @HIRN_CC
Please RT
https://t.co/co9JLJVRIM
Excited to share recent @NatureComms work, led by @rdalbanus (collab with @kitzmanlab)! Information theory applied to ATAC-seq data measures TF-chromatin interaction patterns, with a metric called chromatin information enrichment (CIE). https://t.co/afbq1apakz
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So happy my wife, a physician, got her covid19 vaccine. There's so many true heroes (including her!) that are getting us through this. Keep digging deep to fight. We're close.
Her vaccination video describing the experience:
https://t.co/2PkbArOHYD
Interested in single-cell multi-omics to dissect mechanisms at GWAS signals?
We'd love to have you on our team - a fun collaboration with @kitzmanlab !
Please apply - details here 👇
@bnwolford Thanks @bnwolford ! I caught up with your talk and just loved it - super relevant PRS work! Congrats to you and the @cristenw lab for all the awesome body of work shared at #ASHG20
Genetic variant effects on gene expression in human pancreatic islets and their implications for T2D
https://t.co/NMREEhH1LO
@anavinuela@varshney_arushi@mvandebunt1