pikipiki

[I AM BLAZE THE CURIOUS⚕️☢️ @Blazethecurious]

DID YOU KNOW??

Naked mole rats break the fundamental biological laws of aging, meaning their risk of dying does not increase as they get older!

​In almost every known animal species, a mathematical concept known as the Gompertz-Makeham law of mortality applies: the older an organism gets, the more likely it is to die. For example, a human's risk of death doubles roughly every eight years after reaching adulthood.

​Naked mole rats completely defy this equation. Whether a naked mole rat is 6 months old or 30 years old (an incredibly long lifespan for a small rodent), its daily statistical probability of dying remains exactly the same. Scientists call this NEGLIGIBLE SENESCENCE, meaning that from a cellular standpoint, they simply do not experience normal biological ageing. Walk with me 👇🏾👇🏾

1. The Molecular Shield Against Cancer:
​Beyond their ageless biology, naked mole rats are practically immune to cancer. Even after decades of observation in laboratory settings and attempts to actively induce tumor growth, researchers have almost never seen a naked mole rat develop a malignant tumor.

​Their secret weapon is an exceptionally thick, gooey sugar molecule that fills the spaces between their skin cells, known as high-molecular-weight hyaluronan (HMW-HA). In humans, hyaluronan helps lubricate joints, but the naked mole rat's version is five times larger and denser. When their tissue cells begin to crowd together, the very first step of tumor formation, the dense HMW-HA molecules trigger a strict biological safety protocol called "early contact inhibition."

The surrounding fluid physically signals the cells that they are out of room, instantly locking up their ability to divide long before they can morph into a tumor.

2. ​The Insect-Like Underground Monarchy:
​If their physiological quirks aren't alien enough, their social structure belongs in a beehive rather than a mammal community. Naked mole rats are one of the only eusocial mammals on Earth, living in highly organized underground colonies of up to 300 individuals governed by a strict, insect-like caste system.

In a typical colony, only one single female, The Queen, and one to three select males are allowed to reproduce. The remaining hundreds of colony members are entirely sterile workers, divided into specialized occupational roles:

A. ​The Diggers: These workers form a literal assembly line in the dark, using their massive, chisel-like teeth (which can move independently like chopsticks) to chew through hard dirt, passing loose soil backward down a human-style bucket brigade line to clear out expanding tunnel systems.

B. ​The Soldiers: Larger, heavier workers who spend their entire lives patrolling the perimeter of the tunnels. Their sole purpose is to put their bodies on the line to defend the colony against invading rufous beaked snakes.

C. ​The Disperser Caste: A rare subset of workers born with unique fat reserves and a powerful urge to wander. They are the only ones who leave the colony entirely to seek out neighboring groups, ensuring genetic diversity across different underground domains.

3. ​Surviving Without Oxygen:
​Because hundreds of these rodents crowd into tightly sealed, unventilated subterranean dirt chambers, carbon dioxide levels regularly skyrocket to toxic levels that would cause instant brain damage or suffocation in any normal mammal.

​To survive these suffocating atmospheric drops, naked mole rats possess the incredible ability to switch off their standard mammalian glucose metabolism entirely. ​When oxygen runs completely out, their organs stop burning glucose and instead begin pumping fructose into their bloodstream, effectively utilizing the exact same metabolic pathway that plants use.

SCROLL DOWN FOR THE CONTINUATION 👇🏾👇🏾

[Prabowo Subianto @prabowo]

14. Anggaran perjalanan dinas: Rp. 20 T per tahun. Ini pemborosan. Harus dicoret. Jika saya presiden, tidak boleh pejabat RI plesiran ke LN.

[pikipiki @vckyrstywn]

@tanyarlfes barusan banget kejadian di cewek gw, wfc di salah satu kopisop semarang, sudah pesan makan minum senilai 96 ribu, tiba2 selang 3 jam di suguhi bill. dengan kesadaran diri, cewek gw order lainnya lagi.

[pikipiki @vckyrstywn]

@creamyberry3118 @sephyrene @yappingfess kalau komunikasinya sejelek itu, berarrti dia belum pantes berkomitmen kak.

[pikipiki @vckyrstywn]

@longlifematcha @tanyakanrl Mungkin maksudnya perbandingan antara pelit dengan perhitungan ya, kalau dilihat dari cerita lu, suami lu itu masuk kategori perhitungan nder

[pikipiki @vckyrstywn]

@raniabhe @RichHealthyFun @txtdrjkt Ada banyak pedagang gerobakan di sono ketoprak, bakso dll yang itungannya murah meriah dibanding tenan² viral/estetik

[pikipiki @vckyrstywn]

@beasttkh @hrdbacot cek ig bekelin kak

[pikipiki @vckyrstywn]

@siskadeviar @jellypastaa Hewan teritorial kak si hippo

[pikipiki @vckyrstywn]

@santaibetul @Esmelapakuda mba nunik keliatan asik banget orangnya ya

[Avelino Guido @AvelinoGuido28]

Adik-adik, kakak-kakak semuanya. Kali ini gw mau bicara tentang sesuatu yang sudah menyiksa rakyat Indonesia selama bertahun-tahun. Bukan korupsi. Bukan inflasi. Tapi sesuatu yang lo rasain setiap kali mau mudik atau liburan dan buka aplikasi Traveloka, lalu langsung menutup aplikasinya lagi karena tidak sanggup melihat angkanya.

Yes. Tiket pesawat domestik Indonesia. Yang harganya bisa lebih mahal dari tiket ke luar negeri. Yang bikin relawan bencana harus muter lewat Malaysia dulu baru bisa ke Aceh. Yang udah dikeluhkan jutaan orang tapi tidak pernah beneran berubah.

Gw udah baca risetnya. Gw udah cek datanya. Dan sekarang gw mau cerita ke lo semua, pelan-pelan, dengan bahasa yang bisa dimengerti semua orang, kenapa ini terjadi dan siapa yang sebetulnya diuntungkan dari penderitaan kita bersama. 🧵

[pikipiki @vckyrstywn]

@tanyarlfes Nder, pacar lu cuma flu, bukan koma.
Gw opname 4 hari dengan kondisi tangan tertancap jarum infus aja masih bisa chatingan sama doi walaupun intensitasnya berkurang drastis.

[pikipiki @vckyrstywn]

@tanyakanrl kalau deket banget dan dia bisa dipercaya, pinjemin aja dengan syarat cerita detail permasalahannya apa, kalau fia ga mau cerita ya ga usah pinjemin, 25 jt itu duit gede coy.

[pikipiki @vckyrstywn]

@tanyarlfes Prinsip gw 'perlakukan orang lain seperti lu ingin diperlakukan orang lain'. Tp ada batasnya, kalau gw jd lu, gw akan menghargai diri gw beserta keluarga gw dengan cara stop bawa² in keluarganya sesuatu. Karena laki lu ga bisa bersikap mirroring atas apa yang lu lakuin.

[pikipiki @vckyrstywn]

@Gahar47492381 @yappingfess kebalik menurut gw, dia udah sebenci itu sama mantan makannya porsi cerita buat nyebut 'kekurangan' si mantan panjang banget.

[pikipiki @vckyrstywn]

@tanyakanrl Aman aja bre. Cewek gw malah ngajarin cara berburu diskon di sopi, dan bangga kalau gw beli sesuatu dpt diskon 🤣🤣

[pikipiki @vckyrstywn]

@tanyarlfes Gw kalau duitnya berlebihan, bakalan beli ini hape karena simply tipis, cakep aja gitu, enak di genggam juga walaupun dipakein case.

Tapi karena gw butuh kamera tele, jadi ya pilihannya selalu jatuh ke pro series.

[pikipiki @vckyrstywn]

@tanyakanrl Kalau trnyta ga ketemu tengahnya, ya ga usah dipaksakan. Daripada saling menyakiti

[pikipiki @vckyrstywn]

@tanyakanrl Gw cowok, gw suka banget sama anak kecil. Tp cewek gw kepikiran untuk childfree(untuk saat ini).
Gw ga mempermasalahkan, karena ya itu rahim dan nyawanya dia.
Kalau gw sebegitunya pengen punya momongan, gw open for option an adoption.

Jadi ya intinya komunikasi aja nder.

[pikipiki @vckyrstywn]

@18fesss Bau napas itu banyak sumbernya nder.
Bisa dehidrasi, permasalahan pencernaan atau mulutnya kotor(ada makanan/karang gigi).

Dan itu baunya beda2 😭
Langsung kasih tau aja pakai bahasa yang baik

[pikipiki @vckyrstywn]

@hherssen @benzwift @yappingfess Bisa kok nder
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