J.S. Vergara

Late Bloomer. Low-time Preference Monk. Trying to age well. Maybe life is a game. “ALL THE WORLD‘S A STAGE, AND MEN AND WOMEN MERELY PLAYERS“

[Tim Denning @Tim_Denning]

Obsess. For f*ck sakes. You only get one life. Don’t screw it up by being normal. Go all in. Act like a psycho. Let people call you insane. Please. I beg you. Obsession is the path.

[J.S. Vergara @venefficcus]

@SGTWipper1Each Living the semi-retired life. Enjoying my work, only in the morning. Afternoons are for my family and me.

[J.S. Vergara @venefficcus]

@epigmenioibarra Demencia boomer

[Salih GÜNEY💙 @seri702]

Evlenirsen pişman olursun. Evlenmezsen de pişman olursun. Çocuk yapsan da yapmasan da pişman olursun. Kierkegaard bunu 200 yıl önce şöyle söylemiştir:
"Neyi seçersen seç pişman olursun. Çünkü sorun tercihlerinde değil yaşanmamış bir hayatı romantize etmendir. İnsan her daim gidilmemiş bir yolu cazibeli ve gizemli bulur. Bu yüzden mesele en doğru seçimi yapman değil. Hangi pişmanlıkla yaşayacağını seçip karar vermendir."
Sen neye karar verdin?

[Camus @newstart_2024]

Jimmy Carr nailed something a lot of us feel but can’t explain.

We’re living better than 99.9% of humans who ever walked the earth, hot showers, modern medicine, endless entertainment, kids that actually survive infancy, yet so many of us feel miserable.

He calls it “life dysmorphia.” We get used to how good we have it (the hedonic treadmill), then compare ourselves to everyone else and tank our own happiness.

As he puts it: happiness = quality of life minus envy.

Marcus Aurelius put it perfectly: “Very little is needed to make a happy life; it is all within yourself in your way of thinking.”

When was the last time you caught yourself feeling unhappy despite objectively having it pretty damn good?

[J.S. Vergara @venefficcus]

@PartidoMorenaMx Politicos y el pueblo. Todos en el mismo barco

[J.S. Vergara @venefficcus]

I asked Grok if high profile individuals use longevity compounds:
Yes, largely — at least for now. The “bio/acc” push highlighted in that post (state programs in Russia/China, big funding from Altman/Bezos/Thiel, etc.) underscores a pattern where high-profile, wealthy individuals and early adopters are aggressively using hormones, pharmaceuticals, and peptides for longevity, performance, and anti-aging, while these remain niche, expensive, off-label, or unregulated for most people.46
What high-profile people are actually doing
•Peptides (e.g., BPC-157 for healing, CJC-1295/Ipamorelin for growth hormone release, GHK-Cu for skin, TB-500): Celebrities and influencers like Jennifer Aniston (weekly injections for glow/skin), Gwyneth Paltrow, Joe Rogan (praised BPC-157 for injury), Khloé Kardashian, and others openly credit them. Biohackers, UFC fighters, and longevity investors use them for recovery, fat loss, muscle, and “rejuvenation.” Many are injected or used in clinics.46
•Hormones/TRT/HGH-related: Testosterone replacement therapy (TRT), sermorelin, tesamorelin, or direct HGH analogs. Common in Hollywood, biohacking circles, and among older high-performers for energy, muscle, libido, and body composition. Andrew Huberman and others have noted that many “Hollywood bodies” involve peptides/hormone optimization.54
•Pharma off-label: Bryan Johnson (Blueprint protocol) spends millions yearly on a hyper-optimized regimen including supplements, rapamycin (mTOR inhibitor for longevity), metformin, and more. Others experiment with NAD+ boosters, senolytics, etc. Billionaires fund or access private clinics for stem cells, organoids, and experimental gene/cell therapies.4
These aren’t always “FDA-approved for anti-aging” — many are used off-label, via compounding pharmacies, or in gray areas (some peptides face bans in sports or regulatory scrutiny).56
Why the gap exists
•Access and cost: Private longevity clinics (e.g., in NYC or via telehealth) cater to the rich. Treatments can run thousands per month. Elites have concierge doctors, frequent testing, and tolerance for experimental stuff.
•Regulation and evidence: Many peptides/hormone therapies lack large-scale long-term human data for healthy aging (risks include unknown long-term effects, contamination in black-market versions, or side effects like joint issues or hormonal disruption). Mainstream medicine focuses on disease treatment, not optimization.
•Awareness and culture: High-profile circles (tech, entertainment, biohacking podcasts) normalize it. “Normal people” often stick to basics like diet/exercise due to cost, skepticism, or lack of access.
•Emerging trickle-down: Some basics (e.g., metformin for some, basic TRT if clinically low-T, or GLP-1 drugs like semaglutide for weight/metabolic health) are more accessible. Bryan Johnson’s protocol has consumer versions (supplements, olive oil, etc.). Telehealth and clinics are expanding, but premium peptides/experimentals stay elite.57
It’s not a total blackout for everyone else. Motivated “normal” people can get TRT via doctors, peptides through certain clinics, or cheaper analogs — but quality, safety, and results vary wildly. The arms race accelerates innovation (potentially cheaper/better options later), but early access is heavily skewed by wealth and connections, similar to how cutting-edge tech or medicine has always worked. Over time, proven safe treatments could broaden, but right now the disparity is real. Always consult doctors — self-experimentation carries risks.

[Libertario 🟨⬛ @QuotesforGoal]

"El estado no produce riqueza, la destruye. Solo los individuos crean riqueza y prosperidad en la sociedad"

Adam Smith

[karma @karma44921039]

Never forget

[J.S. Vergara @venefficcus]

@martinvars Hora de buscar modelos para correr localmente

[Dan Go @CoachDanGo]

At midlife, the Greeks believed true awakening began.

Only then had a person lived enough to question their deeper purpose.

They called it Metanoia, meaning a transformation of the heart, a rebirth of the soul.

[J.S. Vergara @venefficcus]

@kuzushi I think the same. It is creative chaos—no rigid rules to follow. Traffic rules are broken every second. Corruption bleeds money through unthinkable wrecks of the system. In some ways, it's the wild, wild west, where you can become rich or die in a car assault

[J.S. Vergara @venefficcus]

@scottmelker In the gardens of Rivendel. Forging the Fellowship
Of the Ring

[Mente Estoico @Mente_estoico]

"Sólo salgo para renovar la necesidad de estar solo."

- Lord Byron

[J.S. Vergara @venefficcus]

@adamemedia1 It is. They would not be speaking in the White House gardens

[Wholesome Side of 𝕏 @itsme_urstruly]

a wise person once said “being hated by idiots is the price you pay for not being one of them” and I’ve been thinking about it ever since.

[J.S. Vergara @venefficcus]

@omgsidewalks Every day

[J.S. Vergara @venefficcus]

@cristiancrespoj De acuerdo. Le faltó magnitud