Lovely to see this one out in @Nature today:
@andygxzeng@MurtazaNagree@asger_jakobsen et al. identify an HSC subset retaining a molecular memory of inflammatory stress. A great collaboration between the @stephxie, John Dick, and @vyas_lab groups.
https://t.co/vJMVMhctsJ
Excited to see our study featured as a Plenary Paper in this week's issue of Blood @BloodPortfolio
https://t.co/aT9L5oSpKj
Podcast episode summarising the findings: https://t.co/VaB64LvVVH
Delighted to see that our work was selected as Plenary Paper in the new issue of Blood! We show that rapid clonal selection foreshadows outcome of IVO+VEN+/-AZA in AML and uncover transcriptional processes altered in resistant clones! @BloodPortfolio
https://t.co/tNWbwhN6To
🧵Just out in Blood @BloodPortfolio: Rapid clonal selection within early hematopoietic cell compartments presages outcome to ivosidenib combination therapy
https://t.co/aT9L5oSpKj
We study how resistance and durable remission emerge in IDH1-mutant AML.
Our paper on detecting and quantifying clonal selection from a single bulk sequencing sample is out! This was a great collaboration with @pvyas_oxford, Thomas Höfer, @asger_jakobsen and @NaserAnsariPour. Read the full story here: https://t.co/bpA30Lyy9Q
@SvenTurkalj kicked off the first session with an excellent talk on his new genotyping method published in @CellStemCell last month 🎉
@MRC_MHU@vyas_lab
https://t.co/jMyukZ6sq6
Delighted to see our paper out today at @CellStemCell ! GTAC integrates #singlecell genotyping to chromatin accessibility profiling, linking genetic and epigenetic tumor evolution. Highlights👇
@pvyas_oxford@asger_jakobsen@angusgroom
https://t.co/fyB1WYXPIK
Fantastic talk by @SvenTurkalj at #ASH22 this morning on our new GTAC method for combining high sensitivity genotyping with chromatin accessibility in single cells!