Liuyang Wang

Human genetics; Statistical genetics; GWAS; Infectious disease; @DukeMGM @DukeMedSchool

BlueSky: @

[Liuyang Wang @wallacewly]

Finally, it is out. Thank @denniskoHiHOST and collaborators, including @Alejand50537855 @DukeCAGPM

[Dennis Ko @denniskoHiHOST]

Our paper on genetic relatedness of 4418 human diseases and traits is out! Select a disease/trait in our webtool (https://t.co/PvZdvTgvd7) and see shared genetic differences with other traits. Subtweets describe discoveries for COVID-19, gout, malaria... https://t.co/IQ7rcqlf4c

[Liuyang Wang @wallacewly]

Good to learn some history

[Steven Salzberg 💙💛 @StevenSalzberg1]

In 1998, I talked to Craig Venter about the feasibility of sequencing the human genome as a whole-genome shotgun project. Here's a story about that conversation https://t.co/ci0kyDHf43

[Jonathan Pritchard @jkpritch]

Our latest preprint revisits the classic model of mutation-selection balance. Do human recessive genes fit Haldane's 100-year old model?

This work is by the wonderful Jon Judd, and co-mentored by Jeff Spence.

[Liuyang Wang @wallacewly]

@MarkTransposon @HanYang_Henry Congrats, Xiekui. Great job!

[Liuyang Wang @wallacewly]

Population-based, first-tier genomic newborn screening in the maternity ward: https://t.co/YjRlcvyBuV

[Liuyang Wang @wallacewly]

@nandangokhale Big congrats, Nandan!

[Liuyang Wang @wallacewly]

@dajiangliu81 @AllofUsResearch @AllofUsCEO This is crazy. A warning notice should be made firstly.

[Liuyang Wang @wallacewly]

@boxiangliu Congrats, Boxiang!

[Dennis Ko @denniskoHiHOST]

What causes differences in biological sex? In our latest preprint, @_AngelaJones takes our lab in a new direction, revealing mechanisms of sex-biased gene expression and identifying abundant sex-biased eQTL throughout the genome (1/6) https://t.co/03ruCbTI9X

[Liuyang Wang @wallacewly]

@meelonmuskusa I saw 56

[Liuyang Wang @wallacewly]

Finally out! We found ferroptosis inhibition reverse aging-exacerbated liver damage, and a gene signature tracks MASLD liver fibrosis and severity, and dysfunction of multi-organs, kidney, heart and pancreatic islet. A nice collab with @kuo_du, @Anna_Mae_Diehl, @denniskoHiHOST

[Nature Aging @NatureAging]

Online now! A new study by @kuo_du et al. shows that aging promotes metabolic dysfunction-associated steatotic liver disease by inducing ferroptotic stress in mice.
(https://t.co/sCOiQsmEXn)
https://t.co/foD6aat3ll

[Luis B Barreiro @LB_Barreiro]

Our most recent work is now published at @NatureGenet. Epigenetic variation impacts individual differences in the transcriptional response to influenza infection. Great collab with @guilbourque lab and huge congrats to the lead author @katiearacena. Link: https://t.co/DxdxSVOqeg

[Liuyang Wang @wallacewly]

@MeisamYsf Congrats!!

[Liuyang Wang @wallacewly]

@YufengFang @KamounLab @dromius @MFSeidl @Taka_Musashi @pskiadas C 位出场👍👍

[Liuyang Wang @wallacewly]

@YiXing77 @NatureProtocols Can I use rMATs for single cell RNAseq?

[Jonathan Pritchard @jkpritch]

It's a pity that All of Us used UMAP to visualize ancestry variation in their new marker paper, out today in Nature.
The UMAP algorithm, by design, exaggerates the distinctiveness of the most frequent ancestries, a message that can be misinterpreted by the public.

[Massimo @Rainmaker1973]

Watch 125,000 years of human migration in 1 minute.

The predicted spread of humans around the globe based on climate conditions over the last 125,000 years.

[📹 Tobias Friedrich]

[Dennis Ko @denniskoHiHOST]

Our latest preprint shows that how strongly a bacterial effector activates its host target is critical: “A single amino acid in the Salmonella effector SarA/SteE triggers supraphysiological activation of STAT3 for anti-inflammatory target gene expression” https://t.co/DIF7olIbSS

[Liuyang Wang @wallacewly]

@jkpritch @tuuliel Yes, please 🙏

[Liuyang Wang @wallacewly]

@zz_zhaozhang Grandchildren, wow!

[Liuyang Wang @wallacewly]

@tangming2005 Congrats, Tommy. Great job!