> I open a PR
> Coworker uses Claude to review. It requests minor changes.
> I fix the comments and request review
> Coworker takes awhile to respond, then uses Claude to review again. It requests minor changes.
This loop has repeated for *two weeks* on a single PR.
This whole thing sucks, and I wish none of it had happened. It’s a really sad day!
But I want to make one thing clear: we’ll keep fighting for open-source AI, harder than ever. This is too important to slow down now. Let’s go!
Browser use has been rolling out in Antigravity, closing the loop between researching, writing code, and verifying it live.
You choose what to log into, downloads pause until you approve them, and the agent can use the browser to run multiple tasks at once. Give it a try today.
Beside all the frontier releases, this sadly gets too little attention. But its super significant what Google released today:
Google DeepMinds AlphaGenome 2 could help researchers find better targets for new drugs by predicting how DNA changes affect specific cells.
The same genetic change can have different effects depending on the cell. Knowing where it acts could help scientists identify which gene or biological process to investigate.
In a test across 28 immune cell types, DeepMind says AlphaGenome 2 identified 30% of variants that causally affect gene activity, compared with 16% for an adapted version of its first model.
It also reproduced a known finding linking a DNA variant to inflammation in gut immune cells. That gives researchers a more specific starting point for testing potential treatments in the lab.
So tl;dr AlphaGenome 2 could help researchers find better drug targets by predicting how DNA changes affect specific cells. Which is super helpful. And since many people asked me recently when we see real value created with the help of AI: Here you go guys.
Congrats @GoogleDeepMind !
Omarchy 4.6 is not just leaning into local AI, but will let you share any model running on any Omarchy machine on your tailnet with another. Get a DGX Spark, then run inference from your XPS13 netbook. Sharing is caring.
@chetaslua superman is the only thing that does not change here. every era gets rebuilt around him, from white blocks to path tracing, and the whole fifty year history is just javascript pretending to be video