nyandika

push it to the limit. man u 4 ever bitch

[MLP Oncología @MLPOncoData]

Coffee and Physical Performance: What Is Driven by Caffeine and What Is Not https://t.co/uMlgr7jHaZ

[nyandika @wi_fihacker]

It’s amazing how mind blowing discoveries as shared daily but ignored for mediocrity.

[nyandika @wi_fihacker]

Accumulation and being first or fast in imagined accolades valued to oblivion.

[nyandika @wi_fihacker]

Waiting for the next Kendrick album is similar to waiting for the next Avengers movie.

[nyandika @wi_fihacker]

“The Carter III” memories!

[nyandika @wi_fihacker]

Anger is laziness directed at the closest target.

[nyandika @wi_fihacker]

How long after completing a good book should you start again?

[nyandika @wi_fihacker]

Sweet aroma of music touching a beating heart with the taste of beautiful sight.

[nyandika @wi_fihacker]

The pressure to keep up with new movies/shows/books, albeit compromising on quality snuffs out the enthusiasm on creating time to enjoy good writing.

[nyandika @wi_fihacker]

Rhapsody lyrics on a Friday hits deep.

[Entisar saleh @Entisar_kilani]

Simplified approach to esophageal and GEJ cancer.
#MedTwitter #Oncology #OncoDaily #nccn

[MV Chandrakanth @ChandrakanthMv]

• In Febrile Neutropenia, the enemy isn’t the most common bug.
• It’s the one that kills first.
• Why we prioritise Gm-neg & anti-pseudomonal cover
• Why Gm pos- isn’t routine
• Why the first 60 minutes matter
👇
#FebrileNeutropenia #Antibiotics #EmergencyMedicine #MVOnco

[nyandika @wi_fihacker]

Demon Slayer - Akaza San

[Typical African @Joe__Bassey]

Many African politicians have been returning home with a goat.

[Dr Rishabh Jain @DrRishabhOnco]

❤️‍🩹Managing Trastuzumab Cardiotoxicity - Made Simple for Clinicians

Trastuzumab saves lives in HER2+ breast cancer, but its Type II, reversible cardiotoxicity needs a proactive plan.
Here’s the evidence-based, practical pathway every oncologist should know 👇🫀

1️⃣ Who’s High-Risk?

• Age >50
• Prior anthracyclines
• Hypertension
• Borderline baseline LVEF
👉 Statins cut risk by 53% (RR 0.47) — strongest cardioprotection we have.

2️⃣ Monitoring That Actually Works

• Baseline + q3-month LVEF
• Know CTRCD: >10% drop to <50%
• Use GLS to catch dysfunction before EF falls 📉

3️⃣ If LVEF Drops

⏸️ Hold trastuzumab
💊 Start ACEi/beta-blockers
📅 Recheck in ~4–6 weeks
✨ Most recover within 6 weeks

4️⃣ The Good News

✔ 88% can safely restart trastuzumab after LVEF recovery
✔ Continue HF meds during rechallenge

🫀 Cardiotoxicity is manageable - cancer outcomes shouldn’t suffer.
Smart monitoring + early intervention = safe, effective HER2 therapy.

🔖 Save this for clinic.
📚 Full infographic below.

#OncoTwitter #MedTwitter #BreastCancer #CardioOncology #HER2 #Trastuzumab @OncoAlert @myESMO @esmo_open @ASCO @EricTopol @CardioNerds @OncBrothers @DrMarthaGulati @DLBHATTMD

[Dr Rishabh Jain @DrRishabhOnco]

🚨 ONCO EMERGENCY: How to Manage EXTRAVASATION in 30 Seconds 🩺💉

Extravasation of chemotherapy = oncology emergency.
Early recognition + immediate action = tissue saved.

Here’s the crisp, protocol-ready approach 👇

1️⃣ STOP Immediately
❌ Stop infusion
❌ Do not flush
✔️ Leave cannula in situ
✔️ Aspirate as much drug as possible
✔️ Mark the area + click a photo

2️⃣ Identify the Agent
Classify the drug:

🔥 Vesicant (DNA-binding / Non-DNA)
😣 Irritant
🙂 Non-vesicant

(Anthracyclines, Vinca alkaloids, Taxanes, Platinum, Mitomycin etc.)

3️⃣ Two Key Pathways

A) “Localise & Neutralise” – DNA-Binding Vesicants
(Anthracyclines, Mitomycin, Dactinomycin)
❄️ COLD compress 20 min × 4/day × 1–2 days

💊 Antidotes:
<3 ml anthracycline → Topical DMSO
3 ml anthracycline → Dexrazoxane (Savene) within 6 hrs
Mitomycin → DMSO

B) “Disperse & Dilute” – Non-DNA Binding Vesicants
(Vinca alkaloids, Taxanes, Trabectedin)
🔥 WARM compress 20 min × 4/day × 1–2 days
💉 Hyaluronidase 150–1500 IU SC around site (5 injections)

4️⃣ Elevate, Analgesia, Plastics Referral
✋ Elevate limb
💊 Analgesics if required
🏥 Early plastics/flush-out team for large-volume or CVAD extravasa
tion

5️⃣ Follow-Up
Mandatory review within 1 week

Patient counselling: monitor for redness, blistering, worsening pain

Document EVERYTHING (site, size, drug, photo, interventions)

💡 TAKE-HOME
Extravasation is rare but high-stakes.
Most injuries are preventable with:
Good venous access
Trained staff
Fast action
Correct antidote pathway
Oncology teams save tissue before they save time. ⏱️🩺

🔖 Save this. Share with your residents and healthcare staff.

#OncoTwitter #MedTwitter #ChemoSafety #Nursing #Oncology @myESMO @OncoAlert @ESMO_Open @asco

[nyandika @wi_fihacker]

In the midst of illness,
Acknowledging the helplessness.
The subjugation to the universe,
Trusting in the ability of self renewal.
Scientifically known but truly unknown
To cure and make whole
“I will push on.”
You whisper.

[nyandika @wi_fihacker]

Even in luck, life happens.

[Court Helicopter News @CourtHelicopter]

Martha Karua Seeks Bond Cancellation in KSh 2.3 Million Car Sale Theft Case

Court heard testimony in a KSh 2.3 million vehicle fraud case where Senior Counsel Martha Karua represents the complainant. The accused, Newton Kimathi Kirimi, appeared virtually despite prior orders for physical attendance, sparking exchanges over outdated medical records.

The DCI Forensic Lab confirmed the accused’s handwriting on the disputed sale documents. Karua urged speedy proceedings, citing delays since 2022. The court ordered the accused to appear physically on 3rd December 2025, warning of bond cancellation if absent.

#CourtHelicopter #MarthaKarua #ThikaCourt #FraudCase #JusticeInKenya

[nyandika @wi_fihacker]

The “good man” or the hemiplegic of virtue…
From the book Will to power.