Witte Lab

Group of genetic epidemiologists @Stanford

[HemOnc Today @HemOncToday]

Genetic adjustment of PSA values may reduce unnecessary testing and increase the detection of aggressive #ProstateCancer tumors, according to research presented at #AACR22

Read more here: https://t.co/oF97iDWzqs

#MedNews @UCSF @UCSFCancer @Linda_Kachuri

[Taylor Cavazos @taylorbcavazos]

The last chapter of my thesis on genetic risk factors for developing multiple primary tumors is now on @medrxivpreprint! Through #WES data from @uk_biobank and @KPDOR, we identify potential pleiotropic variation in individuals with multiple cancers. @johnwitte @LoriSakoda

[Human Genetics and Genomics Advances @HGGAdvances]

New! Genomic analyses from Jiang et al. suggest that genetics could help guide clinical management of #prostate cancer
#OA @johnwitte @WitteLab
https://t.co/QCCcCaOCkU

[Taylor Cavazos @taylorbcavazos]

#ASHG21: Excited to share our work on #cancer #genetics of multiple primary tumors in two large cohorts tomorrow (10/19) at 11:45am EDT! #PrgmNr1015

Big thanks to our collaborators at @KPDOR and @RegeneronDNA. @johnwitte @WitteLab @UCSFCancer https://t.co/lS3X42C28t

[Kirsten Bibbins-Domingo @KBibbinsDomingo]

We ❤️ postdocs @UCSF_Epibiostat @PostdocsUCSF

Meet Dr Jovia Nierenberg @JoviaNierenberg working with @WitteLab & Dr Elad Ziv

https://t.co/gue3cpUQAO

Human genetics & Disease risk (and cool prior work on hypertension)!

[Kirsten Bibbins-Domingo @KBibbinsDomingo]

Dr Rebecca Graff @RebeccaEGraff joined our faculty @UCSF_Epibiostat after her postdoc with @WitteLab

She’s a cancer genetics epidemiologist with a focus on prostate cancer & @PCF_Science 2020 Young Investigator awardee!

More here: https://t.co/Wv7i0znMwF

[Witte Lab @WitteLab]

New @WitteLab paper on cfDNA in prostate cancer by @emmalyn_chen (happy birthday!), @clintcario , @pcarroll_ et al. Targeted cfDNA sequencing can detect somatic tissue alterations in heterogeneous, localized disease. https://t.co/m3d7yw8CnM @UCSF_Epibiostat @UCSFCancer

[Witte Lab @WitteLab]

New @WitteLab study led by @nima_genome and @taylorbcavazos finds novel loci and genes associated with prostate cancer in over 200,000 men from @uk_biobank and @KPDOR. @UCSFUrology @johnwitte https://t.co/oTaV1lDgZX

[Witte Lab @WitteLab]

Congratulations to @ErinNGilbertson for receiving an NSF Honorable Mention! This is a significant national academic achievement and we @UCSF are proud of Erin.

[Witte Lab @WitteLab]

New @WitteLab paper on cfDNA in prostate cancer by
@emmalyn_chen, @johnwitte, @felixfengmd. While cfDNA concentration predicts mets, it has limited diagnostic ability for localized dx. But fragment size may distinguish localized dx. https://t.co/e3pnDo31xI. @UCSF_Epibiostat

[Witte Lab @WitteLab]

Exciting findings from @WitteLab collaboration with @KPDOR led by @RebeccaEGraff shows cross-phenotype PRS effects may enable a more integrated model of cancer risk prediction, and inform new strategies toward reducing the burden of cancer. @LoriSakoda @johnwitte @taylorbcavazos

[Nature Communications @NatureComms]

Evaluating cross-cancer relationships of polygenic risk scores for 16 cancers in two large cohorts.

@RebeccaEGraff, @johnwitte, @LoriSakoda, @WitteLab, @KPDOR

https://t.co/FtYb0944gO

[Kaiser Permanente Research NorCal @KPDOR]

Today in @NatureComms: "patterns of pleiotropy that have the potential to inform investigations of risk prediction, shared etiology, & precision #cancerprevention strategies." @LoriSakoda @KPDOR @kpnorcal @RebeccaEGraff @johnwitte @WitteLab #cancer

Study: https://t.co/Yo2bqkiMSV

[ASHG @GeneticsSociety]

Don't miss out on our first ever @HGGAdvances Journal Club, "Improving Transferability of Polygenic Risk Scores" tomorrow at 12 PM Eastern! @johnwitte and @taylorbcavazos will discuss their paper before taking questions from the audience.

https://t.co/Cv6IrOX6gz

[Witte Lab @WitteLab]

Arun's on twitter at @ArunMajum

[Witte Lab @WitteLab]

New paper by @WitteLab alum Arun Majumdar develops a more powerful two-step approach to detect GxE interactions across multiple traits. @bpasaniuc @johnwitte https://t.co/U9uWsLONs7

[Witte Lab @WitteLab]

New paper by @WitteLab alum Arun Majumdar develops a more powerful two-step approach to detect GxE interactions across multiple traits. @bpasaniuc @johnwitte https://t.co/U9uWsLONs7

[Human Genetics and Genomics Advances @HGGAdvances]

Be sure to register for our upcoming journal club featuring @johnwitte & @taylorbcavazos!

[ASHG @GeneticsSociety]

Mark your calendar for our first Inside @HGGAdvances on January 26 at 12 PM Eastern as @johnwitte and @taylorbcavazos discuss their paper, "Improving Transferability of Polygenic Risk Scores." Register now.

https://t.co/uFam048n1U

[Taylor Cavazos @taylorbcavazos]

Grateful for the opportunity to share my recent work through the ASHG Journal Club! Register below to attend. 👇

@HGGAdvances @UCSFGradDiv @UCSF_Epibiostat @WitteLab

[Witte Lab @WitteLab]

Great video and blog post by @Linda_Kachuri explaining results from our recent paper showing how PRS improve cancer risk prediction. Watch it here and read the story behind the paper: https://t.co/nRq5bUT9r0
@johnwitte @Mattias31

[Witte Lab @WitteLab]

New @WitteLab paper from PhD student @taylorbcavazos on improving transferability of polygenic risk scores. @johnwitte @UCSF

[Taylor Cavazos @taylorbcavazos]

Thrilled to have my 1st PhD paper published at @HGGAdvances! Here, we provide further evidence to support the push towards inclusivity in GWAS showing variants identified in diverse populations may be necessary to achieve equality in PRS prediction. https://t.co/Tyci3DWz24