wolphie

deeptech, entrepreneurship and the occasional post I'll regret in 5 years

[Dustin @r0ck3t23]

Jensen Huang just called the exact top of the pharmaceutical industry.

Not a pivot. Not a disruption.

An extinction event.

Huang: “Where do I think the next amazing revolution is going to come? And this is going to be flat out one of the biggest ones ever. There’s no question that digital biology is going to be it.”

The medical establishment has spent centuries playing a chaotic game of trial and error.

We’re about to mathematically engineer the human operating system.

Huang: “For the very first time in human history, biology has the opportunity to be engineering, not science. When something becomes engineering, not science, it becomes less sporadic and exponentially improving.”

Biology is no longer the dark art of random discovery.

It’s a predictable, compounding execution loop.

Translate the chaotic variables of chemistry into the laws of computer science and you stop waiting for accidental breakthroughs.

You simply compute the cure.

That line should terrify every pharmaceutical executive alive.

Huang: “It can compound on the benefits of the previous years. And every researcher’s contributions compound on each other.”

For decades, drug discovery has been an isolated, artisanal process.

One lab. One team. One molecule. Years of blind iteration.

The algorithm just shattered that entire bottleneck.

Every failed protein fold, every successful synthetic molecule instantly trains the foundational model.

Makes the next iteration mathematically smarter.

Huang: “We’re going to have incredible tools that bring the world of biology, which is very chaotic and constantly changing and diverse and complex, into the world of computer science. And that is going to be profound.”

Incumbent pharma looks at the human body and sees an unmanageable wall of variables.

Engineers look at that exact same body and see raw data waiting to be compiled.

No longer guessing how a molecule will react in the physical world.

Running millions of zero-cost simulated iterations before a single test tube is ever touched.

Rip the chaotic friction out of the physical lab and drop it directly into a massive GPU cluster?

The timeline to map, edit, and optimize the biological machine doesn’t shrink.

It collapses.

[wolphie @wolphiekun]

@neodfrntdrmmr @cmclymer The man might be old enough to have experienced being saved from Iraq by the US. Maybe that’s coming through in his voice.

[wolphie @wolphiekun]

@bryson_tille My business without superwave is like a car without a car

[wolphie @wolphiekun]

When I was 22 people my age were posting about their stupid fucking desserts on twitter. I love seeing this shift in culture. I was 28 before I learned to meditate and saw the benefit. Have had to learn it multiple times bc life. Personal development, when done right, improves the world and not just yourself, as this post is proof of.

[wolphie @wolphiekun]

@levelsio Probably Poland

[wolphie @wolphiekun]

@Doctorbash @elonmusk Hm, sounds like a cultural problem

[wolphie @wolphiekun]

@Martellfox Thanks for speaking out!

[wolphie @wolphiekun]

@LeeviEerola Yup, this works!

[wolphie @wolphiekun]

Look into shadow work, griev properly, give yourself wide allowance to feel whatever it is you’re feeling without judgement and try to actively let your emotions out. I would recommend joining a men’s circle and openly sharing in what is coming up without judgement.

You loved them, which is why you’re hurting. That’s beautiful. Many would unfortunately not care or be happy when their parents pass. Cherish those memories. Feel free to DM for more

[wolphie @wolphiekun]

@andnowsheisnot @raagulanpathy Lol short term memory be like that some days 😂 thx bro

[wolphie @wolphiekun]

@LanceSeidman @sama Thanks for replying. I hope you found a great alternative path if YC didn’t work for you 🙏

[wolphie @wolphiekun]

@LanceSeidman @sama This sounds very interesting. Would you mind elaborating more on this? I’m a founder considering YC

[wolphie @wolphiekun]

@ZssBecker Congrats! Of course this guy focuses on getting the right team in place

[wolphie @wolphiekun]

@PaulHook_em @elonmusk What the actual fuck

[wolphie @wolphiekun]

@elonmusk Showcase of what it means to have leverage… holy damn this guy makes shit happen

[wolphie @wolphiekun]

@sama This is awesome! Been waiting for this! Dad jokes with a particularly annoying twist - en masse!

[wolphie @wolphiekun]

@ZssBecker Just ran 10k! Good luck with the crunch!

[wolphie @wolphiekun]

@ZssBecker Man has got to have mastered the concept of allostatic load to succeed with that routine!

[wolphie @wolphiekun]

@cto_junior @far__el @sama 😂