xuzhaojin

知命认命。

[宇峒 @xYsfknBXPT6M0jo]

N-乙酰 L-半胱氨酸 (NAC) 是一种如此强大的补充剂，应该每天使用。

大制药公司 2021 年试图禁止它的原因是有道理的……

- 分解粘液
- 对皮肤、头皮屑、感冒有益
- 抗氧化剂 & 抗炎

[owen欧文 @cngaohui]

不要崇拜任何人，

李敖的这些话，真的是至理名言，

这个世界是个弱肉强食的社会，

如果你是个羔羊，别人是豺狼的话，你很难爬到社会的顶层。

[温呃某 @Lilanlannr9g]

读到这就能感受到江泽民的宠辱不惊与强大精神内核，被批斗完，见到老朋友，摘掉打着叉羞辱他的牌子，平静从容地去吃饭叙旧谈天说地，即使扫厕所都能干得有板有眼，这就是江泽民

[Dalton (Analyze & Optimize) @Outdoctrination]

Glycine is one of the most powerful anti-aging tools in existence.

It has lifespan extending properties (>28% in some) across several species.

The main reason? It buffers excessive methyl groups from methionine, which can be highly damaging to health in the long run by promoting mTOR, insulin resistance and inflammation.

[ADONIS @adonispara]

Napoleon did an insane amount of reading throughout his life and at some point he even had commissioned a custom traveling campaign library. a book carriage that traveled with his army during battles. this is how Napoleon’s secretaries and companions describe his reading.

[Roger S. McIntyre, MD, FRCPC @rogersmcintyre]

Every few decades a potentially transformative study result appears in psychiatry. These results in JAMA Psy indicate that GLP1s reduce all cause mortality
25% In bipolar disorder, schizophrenia and MDD!

https://t.co/YFOuunKLjv

And accompanying podcast

https://t.co/e5XcrFVuxD

[Truth @TENPHOENIX2018]

旧时代人人分蛋糕，新时代少数人做蛋糕。

[王发财 @izjing888]

为什么现在很多人推崇国外原版教材？

[Nicolas Hulscher, MPH @NicHulscher]

Pfizer gave over 13,000 women DISABLING BRAIN TUMORS with their birth control injections used by 25% of women.

A MASSIVE study of 61 million women found Depo-Provera shots increased the risk of MENINGIOMA by 143%.

Criminal enterprise Pfizer now faces an AVALANCHE of lawsuits.

[Dr Güçlü Ildız @drildiz]

🔻 RESMİ OLARAK AÇIKLANDI!!!

Pfizer, «COVID AŞISI»NIN OLASI YAN ETKİLERİNİN LİSTESİNİ YAYINLADI!!!

1) Kan pıhtısı,
2) Akut böbrek yetmezliği,
3) Akut miyelit,
4) Pozitif anti-sperm antikorları,
5) Beyin sapı embolisi,
6) Beyin sapı trombozu,
7) Kalp krizi (yüzlerce vaka),
8)kalp yetmezliği,
9) Kalp ventriküler trombozu...
10) Kardiyojenik şok,
11) Merkezi sinir sistemi vasküliti,
12) Yenidoğan ölümü,
13) Derin ven trombozu,
14) Beyin sapı ensefaliti,
15) Hemorajik ensefalit,
16) Frontal lob epilepsisi,
17) Epileptik psikoz,
18) Yüz felci,
19) Fetal distres sendromu,
20) Gastrointestinal amiloidoz,
21) Genelleşmiş tonik-klonik nöbet,
22) Hashimoto ensefalopatisi,
23) Hepatik vasküler tromboz,
24) Zona reaktivasyonu,
25) * Kanser reaktivasyonu...
26) Turbo kanserler,
27) Bağışıklık aracılı hepatit,
28) İnterstisyel akciğer hastalığı,
29) Juguler ven embolisi,
30) Juvenil miyoklonik epilepsi,
31) Karaciğer hasarı,
32) Düşük doğum ağırlığı,
34) Çocuklarda çoklu sistem inflamatuar sendromu,
35) Miyokardit,
36) Yenidoğan nöbeti,
37) Pankreatit,
38) Zatürre,
39) Ölü doğum,
40) Taşikardi,
41) Temporal lob epilepsisi,
43) Testis otoimmünitesi,
44) Trombotik inme,
45) Tip 1 Diyabet mellitus,
46) Yenidoğan ven trombozu,
47) Vertebral arter trombozu,
48) Perikardit,
49) Ani bebek. Ölümleri

⟁

[Patrick Boyle — e/🦀 @p_maverick_b]

Remember that many people undoubtedly tried these antibodies, noticed they didn’t work, and didn’t say anything about it because reagents failing to do the thing they’re supposed to do is unfortunately extremely common in biology

[池谷裕二 bot @ikegaya_yuji]

【口の中の細菌が、脳の血管まで旅をして血栓を作っていた！】重度歯周病患者の脳梗塞の血栓を調べたところ、口内細菌のタンパク質が多数検出され、脳梗塞への関与が示唆された。Transl Stroke Res誌 https://t.co/pFLsbgiL0l

[7w 🕊️ @Btc8888XF]

千亿富豪郭广昌：有钱了绝不“还乡”！只因人心太难测

上海前首富、复星老板郭广昌，被央视当面质问：
妈妈一直希望你多回馈家乡，你为什么不干？

他直接回怼：
“家乡太复杂。亲戚一堆，你做不做都麻烦。我只让父母衣食无忧、健康就行，绝不显摆有钱、绝不高调做慈善。光宗耀祖？背后就是装！我干嘛要装？”

穷不串门，富不还乡。
这人把老祖宗的话活成了现实。

你觉得他冷血，还是太清醒？

[Jota @jota_snchez]

Un profesor de Stanford que lleva 30 años estudiando las emociones afirma que suprimir lo que sientes te daña la salud, la memoria y tus relaciones.

6 hallazgos sobre cómo gestionas tus emociones:

1. Reprimir te vuelve literalmente más torpe.

[每日竟赛 @4XX4B1]

原来姐妹引以为傲的身材，生产时候是如此暴力。。。 看着让人脊背发凉🤦‍♀️

[Sholto David @addictedtoigno1]

A few months ago I was browsing google images looking at p53 western blots in the SK-OV-3 cell line for an unrelated project. I noticed an unusual western blot hosted on Thermo Fisher's website which I posted on social media. Usually I just post weird blots to PubPeer. 👇

[Moosa @questmoosa]

Vitamin E and prolactin

In this study, 300 mg’s of vitamin E for 8 weeks, decreased prolactin levels by a staggering 69% when compared to placebo in healthy human subjects.

That’s a massive decrease. One that is hard to obtain with strong medications for such purposes.

[有好信博｜『体力がすべて』 @AriyoshiMd]

大型プールには、尿が30〜75L入っていたと推定

人工甘味料のアセスルファムKは、体内でほぼ代謝されず尿に出る。研究者はこれを尿の目印にした。

カナダのプールとジャグジー31か所から250超の水試料を採取すると、すべてから検出され、濃度は給水用の水道水の4〜571倍。

さらに、42万Lと84万Lの大型プールを3週間調べたところ、含まれる尿はそれぞれ約30L、75Lと推定された...

[Niko McCarty. @NikoMcCarty]

How can one measure the speed of a ribosome?

One option is to use a microscope. Take some human cells and add 'loops' of RNA to them. Each loop has 321 codons and encodes ten copies of a small peptide, called a SunTag.

These RNA loops do not have a stop codon. Ribosomes in the cell grab onto them, begin translation, and then go around the loop again and again. Each time a ribosome completes one cycle, it makes ten SunTags.

As soon as a SunTag is made, it 'sticks' to the ribosome; there is no stop codon to trigger its release. Then, this SunTag gloms onto an antibody, fused to GFP, floating nearby.

As the ribosome goes around the loop, its chain of SunTag grows longer. More copies of GFP grab onto the peptide chain, and the perceived brightness of the ribosome, when viewed under the microscope, grows accordingly.

By measuring how quickly the ribosome's brightness changes, one can calculate its speed:

First, figure out the brightness of a single GFP. You can do this as a control experiment. Then, knowing that a single loop has 321 codons, and that this creates 10 SunTags, you can deduce that one SunTag (and thus one GFP) corresponds to 32 codons.

Finally, by watching the brightness change over time in steps, or chunks, and multiplying by 32, you can back-calculate to figure out how many amino acids are added by the ribosome each second. The answer, in this experiment, is 2.6.

Video below. Green is the GFP. Red is a tag for the RNA loops.

[Master Metabolism @lowmegatron]

“Low thyroid is probably the most common thing associated with just ordinary eczema. And that's because when your thyroid is low, the circulation to your intestine is poor, the serotonin is high, and this combination of endotoxin and serotonin, for example, causes the skin to have abnormal growth patterns.

[Would psoriasis then be in the same category?]

I think so.” — Ray Peat

“My average temp before T3 (thyroid hormone) was 96.4, now it's 98.6. A patch of 30 year old psoriasis on my leg disappeared over a few months of T3.” Facebook comment

“There is a high prevalence of Hashimoto's Thyroiditis in psoriatic patients, especially in women.”

Ref: Prevalence of Hashimoto's thyroiditis in psoriasis patients