🚨preprint🚨
Read our new work on reactive metallo-scaffolds (r-mS)! We combine metal complexes with chemoproteomics to discover new liganding sites across the proteome! Shout out to a great collaboration with GSK! Fantastic team effort 🫶🏻https://t.co/uZUsXthRIU
EMBL’s AI initiative strives to transform all areas of life science research through full AI integration.
Major funding from the Hector Foundation is dedicated to attracting interdisciplinary talent and boosting infrastructure, training, & innovation.
https://t.co/5yZvUStvBk
📣Preprint 📣
You want to degrade a protein in Gram-negatives? We have tackled this challenge! Detailed study of our Light-Activated Metal-Dependent Protein Degradation LAMP-D system in targeting and rescuing NDM-1 activity. What an amazing team effort 🫶🏻 https://t.co/hjjhphljjc
Join our lab, as a S/PLRS @TheCrick /KCL -Synth. Chemist/Chem. Biologist #chemtwitter#chemistry, to lead projects, build teams, support and train, collaborating across my group and more widely, driving forward basic+translational science https://t.co/DSc9Cax4Xk closes 25/6! 24mo
Small proteins can be more complex than they look!
We know proteins fluctuate between different conformations- but how much? How does it vary protein to protein? Can highly stable domains have low stability segments? @ajrferrari experimentally tested >5,000 domains to find out!
🚨Less than a week left to apply (deadline 19/03/25) for this exciting fully funded 4 Year Phd position in my group.
Multidisciplinary project on the design of novel metallo-NBTIs including all the fun of chemistry and much more! Please RT!
Apply here: https://t.co/5SyA3deWs8
Super excited to preprint our work on developing a Biomolecular Emulator (BioEmu): Scalable emulation of protein equilibrium ensembles with generative deep learning from @MSFTResearch AI for Science.
#ML#AI#NeuralNetworks#Biology#AI4Science
https://t.co/yzOy6tAoPv
📣Reminder📣
AI-First Drug Design: Accelerating the Discovery of New Therapeutics | https://t.co/PtkgEbayed
Thu, Dec 12, 2024
8 AM PST / 11 AM EST / 5 PM CEST
Rebecca Paul will share her insights on how AlphaFold 3 and other breakthrough AI models are applied in drug discovery.
Today we’re previewing NeuralPLexer3 Beta: demonstrating unprecedented accuracy and speed in predicting protein-drug complexes, with instant and accurate structural insights across the full range of protein classes and drug molecules.
Learn more:
https://t.co/wBKvomRTJG