Yongjun Cha

Medical Oncology, Center for Colorectal Cancer, National Cancer Center Korea

[Timothy Jenkins @TimothyPJenkins]

Thrilled to announce our paper, "De novo-designed pMHC binders facilitate T cell-mediated cytotoxicity toward cancer cells," is officially out in @ScienceMagazine!

We used generative AI to build a 'GPS' for immune cells to hunt cancer.

Read it here: https://t.co/T7rfR8uK8M

[Paul Brennan @Lyonpaul]

Accelerated preview of Mutograph paper on colorectal cancer published in @Nature today. Results suggest that increase in early onset colorectal cancer may be linked to childhood exposure to some types of E.Coli bacteria that produce genotoxin colibactin. https://t.co/M4NlLgbJ2m

[bioRxiv Cancer Bio @biorxiv_cancer]

The Curated Cancer Cell Atlas: comprehensive characterisation of tumours at single-cell resolution https://t.co/1HmUt6vRJb #biorxiv_cancer

[Joachim Schork @JoachimSchork]

I've recently discovered a really useful R package by Jan Broder Engler called tidyheatmaps. It's designed to make creating heatmaps from tidy data easy, especially for publication-quality visuals. The package uses pheatmap for detailed heatmaps with less coding.

If you work with data like gene expression, you can get a heatmap set up quickly. The usage is straightforward, allowing for quick customization of your heatmaps.

Check out the full guide for all options: https://t.co/imJP1uO2hA

Give it a try for your next data visualization task. It could be a game changer for presenting your data.

If you're interested in statistics, data science, and programming, you might also enjoy my free newsletter where such topics are covered regularly.

More information: https://t.co/X93SeCe0rb

#programmer #Rpackage #coding

[Cancer Cell @Cancer_Cell]

Online Now: The hallmarks of cancer immune evasion https://t.co/2MX95celzx

[Rommie Amaro @RommieAmaro]

Join our @ncats_nih_gov workshop 23-24 Oct
💫In Silico Drug Discovery

w/ Nobel laureate David Baker @UWproteindesign @wpwalters @biogerontology @CherylArrowsmi1 @biobryn @jchodera @GisbertSchneid1 @Rbaltman @collabchem @cwcoley

Free! Virtual! Come!
https://t.co/pJ9Bs7xdpH

[ChainReaper @_Chain_Reaper_]

A key highlight of the 8th Annual #MSKcolorectalCME is the live surgical cases streamed from MSK’s ORs, showcasing advanced techniques like Robotic TME, CME, and lateral pelvic lymph node dissection.

Secure your spot today: https://t.co/Q3YRIJS0GB

[Eric Topol @EricTopol]

New @Nature
The largest study of impact of dietary restriction (DR) in ~1,000 mice with diverse genetic background for health and lifespan
https://t.co/aNXhNxnc5A
—40% caloric restriction had the most lifespan expansion effect but suppressed immune response and loss of lean muscle mass
—a divergence of health and longevity effects of DR
—"genetic background proved to be the more important factor in determining lifespan."

[Ludwig Cancer @Ludwig_Cancer]

A Ludwig @UniofOxford study punctures a longstanding assumption about the source of the genome's most common type of mutation. Its findings have implications for our understanding of not only cancer biology but also carcinogenic risk & drug resistance. https://t.co/dOJCmF59un

[David S. Hong MD @DavidHongMD]

The 🤴 of CRC! The man the myth @skopetz @MDAndersonNews

[Vivek Subbiah, MD @VivekSubbiah]

⭐️Oncology Accelerated Approval Confirmatory Trials: When a Failed Trial Is Not a Failed Drug | Journal of Clinical Oncology @GautamMehtaMD @JCO_ASCO

https://t.co/DBqx0gaZSe

[Florian Krammer @florian_krammer]

I loved reading The Vegetarian, really intense book. Congrats.

[nature @Nature]

Nature research paper: CTLA4 blockade abrogates KEAP1/STK11-related resistance to PD-(L)1 inhibitors https://t.co/6WUvrOsQCo

[Jake June-Koo Lee @jakelee0711]

A beautiful story by @FaltasLab on mutational processes in urothelial cancers. Elegant demonstration of fitness benefit of CCND1 ecDNA during chemotherapy. We will learn a lot from WGS of clinical samples re interactions btw treatment and cancer genomes. Congrats to the authors!

[Michael Papanicolaou @micpapanicolaou]

1/We are delighted to announce that our work “Lung-resident alveolar macrophages regulate the timing of breast cancer metastasis” has been published @CellCellPress.
https://t.co/vi7UxaPQ1d

We show how alveolar macrophages are a barrier to breast cancer lung metastasis. 🧵

[Toni Choueiri, MD @DrChoueiri]

Important White Paper for all trainees on understanding & supporting International Medical Graduates in Oncology. Thank you @ASCO @JCOOP_ASCO for all the support! @IMG_Oncologists

LINK TO COMMUNITY OF PRACTICE PAGE: https://t.co/YYEBp5jguG

[Anirban Maitra @Aiims1742]

Nice to see the final version of this @CD_AACR paper. The triangles made it to the title page (IYKYK)!
Mechanisms of Resistance to Oncogenic KRAS Inhibition in #PancreaticCancer
https://t.co/9Lli1QofiF

[The Lancet Gastroenterology & Hepatology @LancetGastroHep]

New @TheLancet - Adam et al - Liver transplantation plus chemotherapy versus chemotherapy alone in patients with permanently unresectable colorectal liver metastases (TransMet trial)

https://t.co/05kYRbhSBK

#CRCSM #LiverTwitter

[Arndt Vogel @ArndtVogel]

ESMO GI 2024 take-home messages: Colorectal cancer
#ESMOGI24
👉more options: Liver transplantation (TRANSMET), ICI combos (Nivo/Ipi; Botensilimab/Basiliximab..), sequential therapy, molecular selection...
@myESMO #ESMOAmbassadors

[Pashtoon Kasi MD, MS @pashtoonkasi]

👇🏾See you at
ISLB 2024

@isliquidbiopsy

Denver, Colorado, USA
November 23-25, 2024