Yoshiharu Muto

Assistant Professor @UTSWNephrology | Focusing on single cell analysis / epigenetics / metabolism, to identify therapeutic targets in kidney diseases

[Yoshiharu Muto @Yoshi_MutoLab]

The first day of my lab at UTSW nephrology. Very much excited to see how it goes !!

[Yoshiharu Muto @Yoshi_MutoLab]

@IsnardPierre1 Wow huge congrats Pierre!! I will read this weekend.

[Yoshiharu Muto @Yoshi_MutoLab]

@LoebLab Congratulations 🎉🍾

[Gabriel Loeb @LoebLab]

Polycystic kidney disease is the most common monogenic cause of kidney failure and affects over 10 million individuals. We've known most PKD is caused by mutations in PKD1 for over 30 years. But how PKD1 prevents disease has remained mysterious, limiting effective therapy.

[Yoshiharu Muto @Yoshi_MutoLab]

@hansul @shumeng Congrats! 🎊🎉🍾

[Yoshiharu Muto @Yoshi_MutoLab]

@realchinz Congratulations! 🎊🎈

[Yoshiharu Muto @Yoshi_MutoLab]

@mesmith428 Great poster presentation!! Congrats @mesmith428 @Zimmermk1986

[Vishal Patel @Vishal_D_Patel]

🧬 In #ADPKD, reduced PKD1 drives cyst growth and kidney failure.

We previously discovered a 55bp cis-repressive element in its 3'UTR.

We now identify the six critical bases—the miR-17 motif—whose disruption or masking restores PKD1 and slows disease.
🔗 https://t.co/hYIveEkPPU

[Yoshiharu Muto @Yoshi_MutoLab]

@samirparikhmd @hansul @UTSWMedCenter Thank you again Samir for the great introduction today! I appreciate your continued support!!

[Samir M. Parikh @samirparikhmd]

Congratulations to ⁦@Yoshi_MutoLab⁩ and ⁦@hansul⁩ on their outstanding presentations today at the ⁦@UTSWMedCenter⁩ New Faculty Forum!

[Kurt zimmerman @Zimmermk1986]

Check out our latest manuscript where we generate a cross model single cell and spatial atlas of mouse PKD!

A cross model spatial and single-cell atlas reveals the conserved involvement of osteopontin in polycystic kidney disease | bioRxiv https://t.co/ICBC4SXIXJ

[Samir M. Parikh @samirparikhmd]

More to come if I ever learn the art of tweetorials.

For now, I'm so grateful to 1st author Vivian Huang @BIDMChealth and our collaborators from @harvardmed @HopkinsMedicine @YaleMed @UCSFMedicine @TuftsMedicalCtr @UW @BUMedicine...and @ScienceMagazine 🙏

[Yoshiharu Muto @Yoshi_MutoLab]

@samirparikhmd @UTSWNephrology @BIDMChealth @harvardmed @HopkinsMedicine @YaleMed @UCSFMedicine @TuftsMedicalCtr @UW @BUMedicine @ScienceMagazine Congratulations 🎊🎉 Beautiful work!!

[Yoshiharu Muto @Yoshi_MutoLab]

@IsnardPierre1 @FabiolaTerzi @ScienceTM Wonderful achievement🎊🎉🍾🍾Richly deserved!!

[Isnard Pierre @IsnardPierre1]

Thrilled to share our work and truly honored to share senior autorship with @FabiolaTerzi ! Thanks @ScienceTM for publishing our work ! https://t.co/hV96gO39Mq

[Yoshiharu Muto @Yoshi_MutoLab]

@IsnardPierre1 @KIReports Congrats 🎉 🎊

[Yoshiharu Muto @Yoshi_MutoLab]

@KanaHelloKidney @slunephrons Congratulations 🍾🎈

[Yoshiharu Muto @Yoshi_MutoLab]

@LoebLab @ASNKidney Congrats 🎉 Well deserved!!

[Yoshiharu Muto @Yoshi_MutoLab]

@Zimmermk1986 @OuhscN Congratulations 🎊🎉 Richly deserved!

[Amanda Clark, MD @AmandaJClarkMD]

Check out our new paper in Pediatric Nephrology assessing NAD Biosynthesis metabolites in pediatric AKI!

[Yoshiharu Muto @Yoshi_MutoLab]

@AmandaJClarkMD Congratulations 🎉🍾