jay

PharmD P3 // Immortal 1 Valorant

[jay @yuza_fps]

@BeLovesAZ @graceswag So your solution to corporate greed is… convincing people to avoid preventive care? You’re a moron.

[jay @yuza_fps]

The decrease in hyperphagia is one of the most meaningful findings in this study. Targeting appetite regulation may provide benefits that go beyond changes in BMI. It'll be interesting to see whether those improvements are held long term.

[NEJM @NEJM]

Among participants 4 to 66 years of age with acquired hypothalamic obesity, setmelanotide, a melanocortin-4 receptor agonist, led to significantly greater reductions in body-mass index and hunger than placebo at 52 weeks. Full results of the TRANSCEND trial: https://t.co/OeRn3ohulJ

[jay @yuza_fps]

Reads more like delayed regulatory adoption than innovation. Bemotrizinol has been part of routine UV protection internationally for years.

[Medscape @Medscape]

The US FDA today added bemotrizinol to the list of permitted sunscreen active ingredients, marking a significant moment in the agency’s efforts to advance sunscreen innovation. Bemotrizinol is the first new active ingredient added to the over-the-counter (OTC) sunscreen monograph since 1999.

Bemotrizinol protects against both ultraviolet A and B rays and has low absorption through the skin into the body, according to the FDA announcement on June 9. The agency considers bemotrizinol generally recognized as safe and effective for sunscreen use by adults and children 6 months and older. Bemotrizinol has been used in Europe and other regions for years. https://t.co/OnVa8lUeTg

[jay @yuza_fps]

👏👏👏

[FOX Sports @FOXSports]

RAUL JIMÉNEZ FIRST-EVER FIFA WORLD CUP GOAL! 🇲🇽

[jay @yuza_fps]

Pretty cool to see the first CKM syndrome guideline released. Medicine is moving toward treating interconnected systems rather than separate diseases.

[AHA Science @AHAScience]

Published today, the first-ever clinical practice guideline on cardiovascular-kidney-metabolic (CKM) syndrome from the American Heart Association and @ACCinTouch.

The focus of this clinical practice guideline is to create a living, working document that provides current knowledge in the field of CKM syndrome aimed at all practicing cardiologists, endocrinologists, nephrologists, and primary care and specialty clinicians who manage these patients.

✍🏼 @ChiadiNdumele @HeartDocSadiya @kardiologykazi @noshreza @virani_md @biykemb @NutritionHF @mandeepbajaj65 @KatherineTuttl8 @RangaswJ @lisaVWMD @KBreathettMD @EmoryFamMed @ShoaClarke @mad_sters @jmortonmd @sripalbangalore @AnumSaeedMD

[Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 @ABsteward]

🆕💥🔴Systematic review & meta-analysis of 8 RCTs (n=2,881) in HAP/VAP:
⏸️ Newer antibiotics offered no significant advantage over generic comparators for 28-day mortality, clinical response, or microbiological response.
✅ Lower nephrotoxicity versus colistin-containing regimens.
✅ Improved microbiological eradication of carbapenem-resistant Gram-negative bacilli. https://t.co/eIczJWO0Mo

[jay @yuza_fps]

VERVE-102 one of the craziest drugs in development rn. Instead of taking cholesterol meds forever, it’s using gene editing to permanently switch off the PCSK9 gene in the liver with one IV infusion. Early trials showed a LDL reduction of up to 62% lasting 18 months so far.

[jay @yuza_fps]

@davebftv Special.

[jay @yuza_fps]

@4TheShoe87 @whoistysean @doc_zee7 Watching a grown man throw his fake values in the trash and crash out. Stagnant nobody whose entire existence is trapped in a high school gym budget. Stay at the bottom where you belong. Rent-free LOL🤣

[jay @yuza_fps]

@4TheShoe87 @whoistysean @doc_zee7 Dropping the R word because you got cleared is peak bitch behavior. You're a grown man throwing a literal tantrum because your feelings got hurt over a thread, unhinged loser. Don't bring this emotional instability to those HS kids you coach. Pray on your pathetic life, coach.😂

[jay @yuza_fps]

@4TheShoe87 @whoistysean @doc_zee7 Watching you desperately throw out medical terms only to collapse into an illiterate, name calling meltdown has been comedy. Your ego completely fractured the second your logic was challenged. Take a deep breath, fix your spelling, and stick to coaching high school sports. LMAO🤣

[jay @yuza_fps]

@4TheShoe87 @whoistysean @doc_zee7 You made a broad claim, got called out, and now you’re throwing out random disorders to reframe it. Nobody denied those disorders exist, that wasn’t the point. You just realized your "people are addicted to being sick" take didn’t hold up, so you’re backtracking mid thread🫵😂

[Pharmacy Times @Pharmacy_Times]

🚨 BREAKING: Retatrutide shows “bariatric-level” weight loss in Phase 3 TRIUMPH-1 trial.
New data suggest one of the strongest weight-loss effects seen yet from a GLP-1–based therapy class.
🔗 https://t.co/vKiVb9WAKM
#GLP1 #Obesity #ClinicalTrials #PharmacyTimes #WeightLoss #Healthcare

[jay @yuza_fps]

@4TheShoe87 @whoistysean @doc_zee7 You started with “people choose to be sick” and now you’re demanding factual nuance after reducing entire medical conditions to “excuses.” That irony is incredible LOL.

[jay @yuza_fps]

@4TheShoe87 @whoistysean @doc_zee7 Every reply gets less informed and more emotional. Interesting pattern.

[jay @yuza_fps]

@4TheShoe87 @whoistysean @doc_zee7 You’re not informed enough on this to be correcting anyone. Bud.

[jay @yuza_fps]

@4TheShoe87 @whoistysean @doc_zee7 Not everything you don't understand is an excuse.

[jay @yuza_fps]

@4TheShoe87 @whoistysean @doc_zee7 If you’ve never had to manage a chronic condition, it’s probably not your place to reduce it to a mindset problem.

[jay @yuza_fps]

The peace I have now came from accepting things I couldn’t change.

[Satoru Mitsuboshi 💫 | 🔍Pharmacist, PhD @3stars67664378]

💉セフェピムの急速静注
- ⚡️敗血症患者 17名のPK解析
- 1-2gを5mLの注射用水で溶解し、5分間で急速投与
- 全身曝露量は点滴と同等であったが、トラフ濃度は個体間で大きなばらつきあり
- 投与時間の短縮、看護師の負担軽減などに有用な可能性