zoldrax

[zoldrax @zoldrax]

@ydeigin @neuralamp4ever Heterochronic head transplantation provides compelling evidence. However, it may be more practical to inject a dox-inducible OKS AAV directly into the hypothalamus and activate it over longer periods than systemic OKS.

[zoldrax @zoldrax]

@QatarClaimhq Dear Qatar Airways Support, my upcoming flight from Phuket (HKT) to Zagreb (ZAG) via Doha (DOH), scheduled for departure on 02 March 2026. If the flight is canceled or disrupted, what options are available to me (rebooking or etc.)?

[Aging Science News @AgingBiology]

CD4⁺ T cells confer transplantable rejuvenation via Rivers of telomeres
https://t.co/xggjyt1SCC

[Alex Zhavoronkov, PhD (aka Aleksandrs Zavoronkovs) @biogerontology]

Great that @elonmusk started thinking about aging

[Alex Zhavoronkov, PhD (aka Aleksandrs Zavoronkovs) @biogerontology]

D2 of ARDD 2025 https://t.co/Tcq70xmWPv

[David Sinclair @davidasinclair]

Still struck by the dramatic effects of psilocybin on mouse health & lifespan 🍄‍🟫

Here’s some info about this molecule & where people obtain it: 🧵…

[Aging Science News @AgingBiology]

Metformin and monkeys: what can we learn about delaying aging?
https://t.co/ixnaGhAV82

[Peter Fedichev @fedichev]

There’s another super-important piece of aging puzzle revealed in a recent paper: with a lot more observations, the mortality hazard of naked mole-rats failed to increase with age. One picture is worth a thousand words.

As many of you know, “the naked mole-rat (Heterocephalus glaber) is a mouse-sized rodent species, notable for its eusociality and long lifespan. Previously, we reported that demographic aging, i.e., the exponential increase of mortality hazard that accompanies advancing age in mammals and other organisms, does not occur in naked mole-rats (Ruby et al., 2018), a finding that has potential implications for human healthy aging. The demographic data supporting that conclusion had taken over three decades to accumulate, starting with the original rearing of H. glaber in captivity. This finding was controversial since many of the animals in that study were relatively young. In the 5 years following that study, we have doubled our quantity of demographic data. Here, we re-evaluated our prior conclusions in light of these new data and found them to be not only supported but indeed strengthened. We additionally provided insight into the social dynamics of captive H. glaber with data and analyses of body weight and colony size versus mortality. Finally, we provide a phylogenetically proximal comparator in the form of lifespan data from our Damaraland mole-rat (Fukomys damarensis) colony and demographic meta-analysis of those data along with published data from Ansell’s mole-rat (Fukomys anselli). We found Fukomys mortality hazard to increase gradually with age, an observation with inferences on the evolution of exceptional lifespan among mole-rats and the ecological factors that may have accompanied that evolution.”

No breakthrough in anti-aging drug development may be achieved before this phenomenon is properly understood and the underlying mechanisms are exploited for radical human life extension (the reference is at https://t.co/lgETGTF3YE).

Please follow, like and repost. Otherwise I will start posting kittens instead of naked mole rats

[Aging Science News @AgingBiology]

Five years later, with double the demographic data, naked mole-rat mortality rates continue to defy Gompertzian laws by not increasing with age
https://t.co/4NIHynCsBe

[Aging Science News @AgingBiology]

Stem cell-derived organoid models: defying the Hayflick limit
https://t.co/BIm462Qveb

[Aging Science News @AgingBiology]

Phenome-wide analyses identify an association between the parent-of-origin effects dependent methylome and the rate of aging in humans
https://t.co/LcgaIj7jFC

[Sebastian S. Cocioba🪄🌷 @ATinyGreenCell]

🇺🇦 #SlavaUkraini

[НУИ ВШЭ @HUI_VShE]

Высшая школа того, чего больше нет

[zoldrax @zoldrax]

Дело раскрыто. Я знаю всех, кто пытался меня убить https://t.co/pd0U2dyRkd via @YouTube

[zoldrax @zoldrax]

@_hscU https://t.co/fMO9S7YeLj

[zoldrax @zoldrax]

@_hscU Вроде, достаточно только Sox2 подкрутить.

"we found that single-locus targeting of Sox2 was sufficient to remodel and activate Sox2, which was followed by the induction of other pluripotent genes and establishment of the pluripotency network" https://t.co/mnjI0gT1PD

[Phillip Compeau @PhillipCompeau]

📣📣📣I'm so happy to announce that our textbook website for Bioinformatics Algorithms has re-launched!

Some big news: we are making our textbook totally FREE -- two chapters live today and more to come.

Lecture videos + links to online courses too!

https://t.co/TBNMrLbQEl

[Alexander Krasovitskiy @tschelovek72]

Горят леса, творят в престольной гадости
И запах безнадежности кругом
Я точно знаю, что все рухнет в августе
Осталось только подождать в каком