GigaDev

Your favorite dev's favorite dev - I orchestrate bits for a living - Building @memetok_app

[GigaDev @0xWolfDev]

I'm of the opinion that there shouldn't really be any special access to contracts that manage user funds

Maybe small things like protocol fees (with some hard-coded bounds), etc...

But upgradeable contracts/core logic changes shouldn't be managed by a multisig

[banteg @banteg]

this level of attack is really scary. to my knowledge, the compromised signers have followed the best practices. they also used different combinations of os, software and hardware wallets, as well as simulated every transaction.

where do we go from here? magical amulets?

[MemeTok @memetok_app]

Turn on notifications
Scroll-Trading launches tomorrow on @monad

[Carlos Simko @Simkocarlos]

https://t.co/7hdLvzkJmq

[GigaDev @0xWolfDev]

@VibeMarketer_ Hook a brother up ser

[GigaDev @0xWolfDev]

@AzFlin I wasn't clowning him ... Just a pretty big leap for your first time

Anyone that's done psychedelics before would not be clowning on someone like that

[GigaDev @0xWolfDev]

@WaiterG What

[GigaDev @0xWolfDev]

@usoppu Find a good girl

[GigaDev @0xWolfDev]

Bro! This is a f***ing hero dose

If it doesn’t help with longevity it’ll at least change his perception of time

[Bryan Johnson @bryan_johnson]

Doing magic mushrooms this Sunday.

Protocol
+ dose: 5 grams
+ frequency: 1x/mo for 3 mo
+ objective: exploring longevity effects

Measurement
+ 249 independent biomarkers
+ 29 vials of blood
+ brain scans
+ urine, stool, saliva, fertility
+ multi-omics profiling (DNA, epigenetics, metabolism, hormones, microbiome, proteins, cognition)

Cardiovascular
+ LDL-C
+ HDL-C
+ Triglycerides
+ Total cholesterol
+ Apolipoprotein B
+ Apolipoprotein A-1
+ Lipoprotein(a)
+ LDL-P
+ HDL-P
+ Small LDL-P
+ LDL size
+ Large VLDL-P
+ Large HDL-P
+ VLDL size
+ HDL size
+ LP-IR score
+ Oxidized LDL
+ Lp-PLA2 activity
+ Myeloperoxidase (MPO)
+ Homocysteine
+ VEGF

Hematology
+ WBC
+ RBC
+ Hemoglobin
+ Hematocrit
+ MCV
+ MCH
+ MCHC
+ RDW
+ Platelets
+ Neutrophils
+ Lymphocytes
+ Monocytes
+ Eosinophils
+ Basophils
+ Immature granulocytes
+ Erythropoietin (EPO)
+ ABO/Rh typing

Hormonal
+ Thyroid panel with TSH
+ Free T4
+ Testosterone
+ Dihydrotestosterone (DHT)
+ 5α-DHT
+ Prolactin
+ Estradiol
+ LH
+ FSH
+ Estrone (E1)
+ Estriol (E3)
+ Androstenedione
+ Androsterone
+ 5β-Androstanediol
+ Etiocholanolone
+ Cortisol
+ Cortisone
+ DHEA
+ DHEA-S
+ Pregnenolone
+ IGF-1
+ Melatonin (6-hydroxymelatonin sulfate)

Metabolic
+ Glucose
+ Insulin
+ Hemoglobin A1c
+ α-Hydroxybutyrate
+ β-Hydroxybutyrate
+ Uric acid

Kidney
+ BUN
+ Creatinine
+ eGFR
+ BUN/Creatinine ratio
+ Cystatin C
+ Urinalysis (specific gravity, pH, color, appearance, leukocyte esterase, protein, glucose, ketones, occult blood, bilirubin, urobilinogen, nitrite, WBC [hpf], RBC [hpf], epithelial cells, casts, bacteria)
+ Albumin/Creatinine ratio

Pancreatic
+ Total protein
+ Albumin
+ Globulin
+ Total bilirubin
+ Alkaline phosphatase
+ AST
+ ALT
+ GGT
+ Amylase
+ Lipase

Minerals
+ Sodium
+ Potassium
+ Chloride
+ CO₂ (bicarbonate)
+ Calcium
+ Magnesium
+ Iron
+ TIBC
+ UIBC
+ Iron saturation
+ Ferritin
+ Zinc

Vitamins
+ Vitamin B12
+ 25-hydroxy Vitamin D
+ Coenzyme Q10
+ α-Tocopherol
+ β-Carotene
+ Glutathione
+ Total glutathione

Amino Acids
+ Cysteine
+ Methionine
+ Taurine
+ Glycine
+ Serine
+ Threonine
+ Alanine
+ Valine
+ Leucine
+ Isoleucine
+ Phenylalanine
+ Tyrosine
+ Tryptophan

Inflammation
+ Interleukin-6 (IL-6)
+ Interleukin-10 (IL-10)
+ Tumor Necrosis Factor-α (TNF-α)
+ Rheumatoid factor (RF)
+ ANA by IFA
+ Calprotectin (GI inflammation),
+ Secretory IgA (mucosal immunity)

Neurology
+ P-tau217
+ Epinephrine metabolites (metanephrine, normetanephrine)
+ Homovanillate (HVA)
+ Vanilmandelate (VMA)
+ 5-Hydroxyindoleacetate (5-HIAA)

Toxicology
+ Lead
+ Lithium

Urology
+ PSA total

Fertility
+ Total Motile Count
+ Sample Volume
+ Concentration
+ Motility
+ Morphology
+ Count

Metabolomics
+ Citrate
+ cis-Aconitate
+ Isocitrate
+ α-Ketoglutarate
+ Succinate
+ Fumarate
+ Malate
+ Pyruvate
+ Lactate
+ 2-Hydroxyglutarate,
+ Hydroxymethylglutarate,
+ 3-Methylglutaconate,
+ 2-Methylsuccinate
+ Formiminoglutamate (FIGLU),
+ Methylmalonate (MMA),
+ Xanthurenate
+ Kynurenate,
+ Quinolinic acid
+ Glucarate,
+ 8-Hydroxy-2′-deoxyguanosine (8-OHdG),
+ Pyroglutamate
+ 3-Hydroxyphenylacetate,
+ 4-Hydroxyphenylacetate,
+ 2-Hydroxyphenylacetic acid
+ 4-Cresol,
+ p-Hydroxybenzoate,
+ Benzoate,
+ Hippurate/Hippuric acid
+ Phenylacetate/Phenylacetic acid,
+ Indoleacetate/Indoleacetic acid
+ Arabinose,
+ Citramalic acid,
+ α-Hydroxyisobutyric acid

Microbiome
+ Bacteroides fragilis
+ Bacteroides vulgatus
+ Faecalibacterium prausnitzii
+ Akkermansia muciniphila
+ Roseburia spp.
+ Eubacterium rectale
+ Lactobacillus spp.
+ Bifidobacterium spp.
+ Escherichia coli
+ Clostridium difficile
+ Enterococcus faecalis
+ Candida albicans
+ Saccharomyces boulardii
+ Prevotella copri
+ Ruminococcus spp.
+ Methanobrevibacter smithii
+ Blautia spp.
+ Proteobacteria spp.
+ Firmicutes/Bacteroidetes ratio
+ Beta-glucuronidase
+ Butyrate
+ Propionate
+ Acetate

Aging & Epigenetics
+ Telomere length
+ Relative telomerase activity
+ DNA methylation age
+ DNA methylation levels at CpG sites associated with biological aging
+ Glucocorticoid receptor methylation (NR3C1)
+ SIRT1 methylation
+ MTOR methylation
+ Oxidative stress response genes (NFE2L2 promoter methylation)

Cognitive
+ Brain age score
+ Functional connectivity strength
+ Global connectivity index
+ Hemodynamic response amplitude
+ Hemodynamic response latency
+ Resting-state oxygenated hemoglobin (HbO) concentration
+ Resting-state deoxygenated hemoglobin (HbR) concentration
+ Total hemoglobin (HbT) concentration
+ Oxygen saturation (O₂Sat)
+ Cerebral blood volume (CBV)
+ Cerebral blood flow (CBF)
+ Neurovascular coupling index
+ Prefrontal cortex oxygenation
+ Parietal cortex oxygenation
+ Temporal cortex oxygenation
+ Occipital cortex oxygenation
+ Task-evoked hemodynamic response (HbO/HbR)
+ Temporal autocorrelation of hemodynamics
+ Functional brain network modularity
+ Inter-regional coherence
+ Brain lateralization index
+ Oscillatory power (slow cortical fluctuations)
+ Phase synchronization index
+ Mean reaction time (during cognitive tasks)
+ Reaction time variability
+ Heart-rate variability (HRV)
+ Resting heart rate

[GigaDev @0xWolfDev]

Sometimes the people closest to an industry are the most clueless about where its headed

[Tanay Jaipuria @tanayj]

The Cursor launch post on Hacker News only had 14 votes and "I still can't figure out if this is just some sarcastic joke software" as the top comment.

Incredible

[GigaDev @0xWolfDev]

@parveen__tyagi Lol I do that every day

[GigaDev @0xWolfDev]

@11AMdotclub We're building something similar guys, on base! How can we get on the pod.

@memetok_app

[GigaDev @0xWolfDev]

@Ganeshuor Found an error right here

[GigaDev @0xWolfDev]

@base @0xNeurobro @talentir_com @Delta3Protocol @aixbt_agent what does this batch say about base’s future?

[GigaDev @0xWolfDev]

Good news coming tomorrow from the @memetok_app team

[GigaDev @0xWolfDev]

@sat0r1x @Jackkk Like 6, sounds legit

[GigaDev @0xWolfDev]

@Jackkk Hahaha you never known right?

[GigaDev @0xWolfDev]

Agreed… check out @memetok_app

[Linda Xie @lindaxie]

Many crypto products will converge on trading + social. Trading is the main revenue driver in crypto and social makes a product stickier but is really hard to bootstrap. Why I'm optimistic about the social graph @farcaster_xyz built over years which is permissionless to leverage

[MemeTok @memetok_app]

Big news Memetok just got accepted into base founder house brazil 🇧🇷🔥

We’re heading to Florianópolis to refine our story, sharpen our GTM, and connect with some of the best builders and investors in the Base ecosystem.

Let’s build the future of social trading on base 🔥

[GigaDev @0xWolfDev]

@m00des @banditxbt Mfer was shilling blast coins. Apparently you can also get smarter

[GigaDev @0xWolfDev]

@ln_dev7 @shadcn @_heyrico Forking right nowwwww