Greg Vardy

founder, Pineridge Capital // prev helped build Ethereum {CTO @Nethermind}

[Greg Vardy @0xGreg_]

Oops, was off by about a decade

[Greg Vardy @0xGreg_]

We've been a part of the OpenAI API beta for a while now, and what I can tell you is that ENTIRE industries are about to be completely re-made in a matter of months.

[Greg Vardy @0xGreg_]

@pmarca Interesting, Gemini refuses this instruction, with this being the offending part of the prompt.. Not surprising.

[Alex Rives @alexrives]

Scaling laws are powering AI. It’s time to scale biology.

Today we’re launching the Virtual Biology Initiative to generate the data to unlock scaling laws in biology and build accurate predictive models of the cell.

Digital representations of proteins are already expanding our understanding of life at the molecular level, and accelerating the design of molecules and medicines. Accurate digital representations of the cell could reveal the mechanisms that are responsible for disease, and show how to reverse them.

The protein data bank, and worldwide repositories of protein sequence biodiversity were created through decades of work by the scientific community. The advances in artificial intelligence for proteins would not have been possible without them.

The cell is orders of magnitude more complex, and we will need to create the data in just a few years rather than decades.

This will require a coordinated global effort. We're partnering with Broad, Wellcome Sanger, Arc, Allen, Human Cell Atlas, Human Protein Atlas, NVIDIA, and Renaissance Philanthropy.

Biohub is contributing to this effort as both a funder and a builder. We are developing microscopy to observe millions of cells in living organisms, and cryo-ET to resolve the cell in atomic detail. We're building instruments that expand the range of modalities and parameters that can be simultaneously measured. We’re developing molecular, cellular, and tissue engineering to create models of disease and design interventions.

The data we generate will be available to the worldwide scientific community.

We’re also committing $100M over the next five years to support work beyond Biohub.

We invite other scientific teams and funders to join.

Link: https://t.co/93Nw1QT5iZ

[Greg Vardy @0xGreg_]

It's surprising that public markets still don't really understand that the demand for intelligence (compute) is functionally infinite, at least from the POV of a Kardashev I civilization, and probably Kardashev II too.

[Logan Kilpatrick @OfficialLoganK]

The compute bottleneck is massively under appreciated.

I would guess the gap between supply and demand is growing single digit % every day.

[Greg Vardy @0xGreg_]

https://t.co/KneZQRmHhK

[Naval @naval]

There is unlimited demand for intelligence.

[Naval @naval]

There is unlimited demand for intelligence.

[Greg Vardy @0xGreg_]

To understand where the economy & society is headed, you at least need to understand that the demand for digital intelligence is unbounded

[Saket Kumar @SaketRKumar]

We just raised $3.5M from @generalcatalyst to kill tax season. Our mission isn't to 'streamline' it, but to delete this problem for Americans. No time. No cost.

(1/5 🧵)

[Nethermind Security @NethermindSec]

Our Formal Verification team has formalized computable multivariate polynomials in Lean. cc @leanprover

This is a foundation for stronger, machine-checked reasoning in zk proofs and protocol design.

🔗 https://t.co/4nQ7AhzWus
1/

[Greg Vardy @0xGreg_]

@annanay Its never too late (to be exit liquidity)

[Julian Sutherland @ ZKProof @JulekSU]

Was amazing working with @RiscZero, particularly @intoverflow and @BruestleJeremy! Great work from my team: @fastreedsolomon and others. Looking forward to applying these techniques to Zirgen! 😁

[Greg Vardy @0xGreg_]

@fastreedsolomon @JulekSU It's beaut, my reaction was: *that's it?!, that's the entire parser?!?!*

[Marc Andreessen 🇺🇸 @pmarca]

Overheard in Silicon Valley: "My biggest lesson from the last year is just, it’s all going to happen. All my childhood dreams of space colonies and brain interfaces and AI and robots. Everything is just… going to happen."

[Greg Vardy @0xGreg_]

@dcbuilder Structure is a really effective way to free up your subconscious to simmer on interesting ideas

[Greg Vardy @0xGreg_]

@quant_arb I see you found an s-tier recruiter

[Greg Vardy @0xGreg_]

@quant_arb Recruiters are power law, most of them are a joke but some are absolutely incredible

[Greg Vardy @0xGreg_]

@yrechtman This was the first thing I thought too😅

[Greg Vardy @0xGreg_]

@nayafia *Straussian nod*